Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Sanjib Bhakta"'
Autor:
Mousumi Shyam, Abhishek Thakur, Caroline Velez, Chris Daniel, Orlando Acevedo, Sanjib Bhakta, Venkatesan Jayaprakash
Publikováno v:
Frontiers in Antibiotics, Vol 3 (2024)
IntroductionIn response to continued public health emergency of antimicrobial resistance (AMR), a significant key strategy is the discovery of novel mycobacterial efflux-pump inhibitors (EPIs) as potential adjuvants in combination drug therapy. Inter
Externí odkaz:
https://doaj.org/article/e0ba094b968c42ef87eafcf5d71e033f
Autor:
Tulika Munshi, Antima Gupta, Dimitrios Evangelopoulos, Juan David Guzman, Simon Gibbons, Nicholas H Keep, Sanjib Bhakta
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0301375 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0060143.].
Externí odkaz:
https://doaj.org/article/15b54048e72b4670b65c82cfd7fc2977
Autor:
Selase Ativui, Cynthia Amaning Danquah, Michael Ofori, Simon Gibbons, Sanjib Bhakta, Peace Doe
Publikováno v:
Research Journal of Pharmacognosy, Vol 9, Iss 4, Pp 21-27 (2022)
Background and objectives: The resistance of infectious pathogens to antimicrobial drugs is an underestimated threat to public health. This rapidly developing phenomenon necessitates the discovery of new treatment strategies. Combining natural compou
Externí odkaz:
https://doaj.org/article/94f63002623f4decbbacaa6b252b82e8
Autor:
Mousumi Shyam, Gourab Bhattacharje, Chris Daniel, Amrendra Kumar, Pragya Yadav, Piyali Mukherjee, Samsher Singh, Amit Kumar Das, Tadigoppula Narender, Amit Singh, Venkatesan Jayaprakash, Sanjib Bhakta
Publikováno v:
Molecules, Vol 28, Iss 24, p 8115 (2023)
The uncontrolled spread of drug-resistant tuberculosis (DR-TB) clinical cases necessitates the urgent discovery of newer chemotypes with novel mechanisms of action. Here, we report the chemical synthesis of rationally designed novel transition-state
Externí odkaz:
https://doaj.org/article/05e022cb8178435aaf84fe49218a3c2f
C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol
Autor:
Liam T. Martin, Eleanor D. Lamming, Arundhati Maitra, Parisa N. Mortazavi, Rebecca Roddan, John M. Ward, Sanjib Bhakta, Helen C. Hailes
Publikováno v:
Frontiers in Antibiotics, Vol 2 (2023)
IntroductionThe emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease which remains one of the leading infectious causes of death worldwide. The development of novel
Externí odkaz:
https://doaj.org/article/b19c3d06f60449e4b8617a588c56b3ec
Autor:
Sarmistha Biswal, Karina Caetano, Diamond Jain, Anusha Sarrila, Tulika Munshi, Rachael Dickman, Alethea B. Tabor, Surya Narayan Rath, Sanjib Bhakta, Anindya S. Ghosh
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 553 (2023)
Class A serine β-lactamases (SBLs) have a conserved non-active site structural domain called the omega loop (Ω-loop), in which a glutamic acid residue is believed to be directly involved in the hydrolysis of β-lactam antibiotics by providing a wat
Externí odkaz:
https://doaj.org/article/681dd803041744f39a53d27fb6efc5d6
Autor:
Cynthia Amaning Danquah, Prince Amankwah Baffour Minkah, Theresa A. Agana, Phanankosi Moyo, Michael Ofori, Peace Doe, Sibusiso Rali, Isaiah Osei Duah Junior, Kofi Bonsu Amankwah, Samuel Owusu Somuah, Isaac Newton Nugbemado, Vinesh J. Maharaj, Sanjib Bhakta, Simon Gibbons
Publikováno v:
Molecules, Vol 27, Iss 14, p 4475 (2022)
Amaryllidaceae is a significant source of bioactive phytochemicals with a strong propensity to develop new drugs. The genera Allium, Tulbaghia, Cyrtanthus and Crinum biosynthesize novel alkaloids and other phytochemicals with traditional and pharmaco
Externí odkaz:
https://doaj.org/article/58a9ea7254d54267a80782231a1a0b15
Publikováno v:
Antibiotics, Vol 11, Iss 1, p 67 (2022)
The consistently mutating bacterial genotypes appear to have accelerated the global challenge with antimicrobial resistance (AMR); it is therefore timely to investigate certain less-explored fields of targeting AMR mechanisms in bacterial pathogens.
Externí odkaz:
https://doaj.org/article/91eddd9a6ba44249b2d1bd43bc4fdf11
Autor:
Cynthia A. Danquah, Eleftheria Kakagianni, Proma Khondkar, Arundhati Maitra, Mukhlesur Rahman, Dimitrios Evangelopoulos, Timothy D. McHugh, Paul Stapleton, John Malkinson, Sanjib Bhakta, Simon Gibbons
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Disulfides from Allium stipitatum, commonly known as Persian shallot, were previously reported to possess antibacterial properties. Analogues of these compounds, produced by S-methylthiolation of appropriate thiols using S-methyl methanethio
Externí odkaz:
https://doaj.org/article/37e1ab0ec36449f69d577c41c3e6f546
Autor:
Cynthia Amaning Danquah, Michael Tetteh, Isaac Kingsley Amponsah, Abraham Yeboah Mensah, Kwame Ohene Buabeng, Simon Gibbons, Sanjib Bhakta
Publikováno v:
Antibiotics, Vol 10, Iss 8, p 902 (2021)
The bulbs of Allium species are a known source of antibacterial phytochemicals. Anti-infective, efflux pump and biofilm inhibitory activities of bulb extracts of selected Ghanaian shallots Allium cepa var aggregatum were evaluated using the HT-SPOTi
Externí odkaz:
https://doaj.org/article/41db70a010d6498d884bf160d33b7651