Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sanjib Bera"'
Autor:
Sanjib Bera
The present paper seeks to explore the paradigms of scientific development in colonial India. The history of colonial India during the eighteenth-nineteenth century spectacularly illustrate a close link between science and imperialism and my endeavor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f746f792dabd886d36b9889aaa4b4c2
Autor:
Vasu Nair, Sanjib Bera
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 24:37-43
Synthesis of acyclic nucleosides bearing a furanyl scaffold is described. The approach involved the construction of the base moiety onto a dihydrofuranyl intermediate. While the A and C analogues did exhibit some substrate activity toward deoxycytidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f090e37a41e19a6220b810733b0e30
https://doi.org/10.1081/ncn-200046782
https://doi.org/10.1081/ncn-200046782
Autor:
Steven S. Carroll, Sanjib Bera, David B. Olsen, Renee Hrin, Joanne E. Tomassini, Malcolm MacCoss, Daniel R. McMasters, Balkrishen Bhat, Michael D. Miller, Leila Malik, Anne B. Eldrup, William A. Schleif, Greg Moyer
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:6237-6247
1,3-Dioxolane and 1,3-oxathiolane nucleoside analogs play an important role in anti-viral and anti-neoplastic chemotherapy. We report here the synthesis of 2-hydroxymethyl-5-methyl-1,3-dioxolanylpurine nucleosides from 4-acetoxy-2-(benzyloxymethyl)-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238bab08e1dc51f83c063d82bcbbcfd9
https://doi.org/10.1016/j.bmc.2004.08.054
https://doi.org/10.1016/j.bmc.2004.08.054
Autor:
Michele Bosserman, Neelima Bhat, Joanne E Tomassini, Sanjib Bera, Marija Prhavc, Christine Burlein, Malcolm MacCoss, Charles R. Allerson, Jennifer L. Brooks, David B. Olsen, Jie Xia, Balkrishen Bhat, C. Frank Bennett, Steven S. Carroll, P. Dan Cook, Quanlai Song, Krista Getty, Anne B. Eldrup, Daniel R. McMasters, Thazha P. Prakash
Publikováno v:
Journal of Medicinal Chemistry. 47:2283-2295
As part of a continued effort to identify inhibitors of hepatitis C viral (HCV) replication, we report here the synthesis and evaluation of a series of nucleoside analogues and their corresponding triphosphates. Nucleosides were evaluated for their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0c81244f104da2508224e92b06686c
https://doi.org/10.1021/jm030424e
https://doi.org/10.1021/jm030424e
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 22:239-247
Novel 3′-substituted isonucleoside analogs were designed on the basis of the similarities of their electrostatic potential with the active anti-HIV compound, (S,S)-isodideoxy-adenosine. The key synthetic step involved coupling between the dideoxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f803ae478ac2a7bebb64808462f5c160
https://doi.org/10.1081/ncn-120021424
https://doi.org/10.1081/ncn-120021424
Autor:
Sanjib Bera, Vasu Nair
Publikováno v:
Tetrahedron. 58:4865-4871
Synthesis of purine and pyrimidine nucleosides with furanyl scaffolds is described. The 2-functionalized tetrahydrofuranol derivatives 12 and 15 were coupled with nucleobases through the Mitsunobu reaction. The methodology developed is general and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::778a4513a5a427c3261f16866f576de5
https://doi.org/10.1016/s0040-4020(02)00430-1
https://doi.org/10.1016/s0040-4020(02)00430-1
Autor:
Sanjib Bera, Vasu Nair
Publikováno v:
Helvetica Chimica Acta. 83:1398-1407
Synthesis of isonucleosides 13, 14, 16, and 17, bearing an exocyclic methylidene group at the sugar moiety, starting from a 3-keto sugar is described. The keto compound was converted to the methylene-sugar 10b (Scheme 1), which was coupled with nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0289cb69035240ed8dfb2af147a6055c
https://doi.org/10.1002/1522-2675(20000705)83:7<1398::aid-hlca1398>3.0.co
https://doi.org/10.1002/1522-2675(20000705)83:7<1398::aid-hlca1398>3.0.co
Autor:
Sanjib Bera, Tanmaya Pathak
Publikováno v:
Tetrahedron. 55:13051-13062
The degradation pattern of the N-oxides of various tertiary aminouridines is established. The N-oxide of 3′-deoxy-3′-morpholino-arauridine generated double bonds in the carbohydrate moiety without much selectivity, whereas epimino uridine N-oxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::756e7b4922ac25b2439c69388e05cc01
https://doi.org/10.1016/s0040-4020(99)00797-8
https://doi.org/10.1016/s0040-4020(99)00797-8
Publikováno v:
Scopus-Elsevier
A bisvinyl sulfone functionality is incorporated into the carbohydrate moiety of uridine to synthesize 6 (or 7) which is a bifunctionalized nucleoside Michael acceptor and has the potential to form covalent bond with biological nucleophiles. This com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e64258fec403f7c920725538185d68
https://doi.org/10.1021/jo9705576
https://doi.org/10.1021/jo9705576
Publikováno v:
Tetrahedron. 51:7857-7866
A reactive triatomic analogue of AZT, 3′-deoxy-3′-(vinylsulphonyl)thymidine has been synthesised from easily accessible starting material. The vinyl-sulphone nucleoside was reacted with a variety of nucleophiles to generate new classes of modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6394dc9227beb417aabc0d112f8fe078
https://doi.org/10.1016/0040-4020(95)00403-u
https://doi.org/10.1016/0040-4020(95)00403-u