Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sanjeewani Sooriyaarachchi"'
Autor:
Wei Sun, Paola Grassi, Ake Engström, Sanjeewani Sooriyaarachchi, Wimal Ubhayasekera, Julius Hreinsson, Kjell Wånggren, Gary F Clark, Anne Dell, Sophia Schedin-Weiss
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29011 (2011)
Protein C inhibitor (PCI) is a serpin type of serine protease inhibitor that is found in many tissues and fluids in human, including blood plasma, seminal plasma and urine. This inhibitor displays an unusually broad protease specificity compared with
Externí odkaz:
https://doaj.org/article/6c431de2c26441b491fbdac07147b67c
Autor:
Jenny Pouyez, René Chofor, Sherry L. Mowbray, Chinchu Johny, Cynthia S. Dowd, Sanjeewani Sooriyaarachchi, Louis Maes, Alexander Alex, Amanda Haymond, Tom Coenye, T. Alwyn Jones, Robin D. Couch, Annelien Everaert, Johan Wouters, Serge Van Calenbergh, Terese Bergfors, Martijn D. P. Risseeuw
Publikováno v:
Journal of medicinal chemistry
Blocking the 2-C-methyl-D-erythrithol-4-phosphate (MEP) pathway for isoprenoid biosynthesis offers interesting prospects for inhibiting Plasmodium or Mycobacterium spp. growth. Fosmidomycin (1) and its homologue FR900098 (2) potently inhibit 1-deoxy-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e393587173a9e692a9502be0a92f13
https://doi.org/10.1021/jm5014264
https://doi.org/10.1021/jm5014264
Autor:
Dan Funck Jensen, Anders Broberg, Sanjeewani Sooriyaarachchi, Mukesh Dubey, Wimal Ubhayasekera, Magnus Karlsson
Publikováno v:
Fungal Genetics and Biology. :33-41
Isocitrate lyase (ICL), a signature enzyme of the glyoxylate cycle, is required for metabolism of non-fermentable carbon compounds like acetate or ethanol, and virulence in bacteria and fungi. In the present study, we investigate the role of the glyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd48cadf83463441585fea4272c6ca13
https://doi.org/10.1016/j.fgb.2013.06.008
https://doi.org/10.1016/j.fgb.2013.06.008
Autor:
Cynthia S. Dowd, Louis Maes, Sanjeewani Sooriyaarachchi, Terese Bergfors, Sherry L. Mowbray, Jenny Pouyez, Johan Wouters, Serge Van Calenbergh, Martijn D. P. Risseeuw, T. Alwyn Jones, René Chofor
Publikováno v:
CHEMMEDCHEM
ChemMedChem
ChemMedChem
Blocking the 2-C-methyl-d-erythrithol-4-phosphate pathway for isoprenoid biosynthesis offers new ways to inhibit the growth of Plasmodium spp. Fosmidomycin [(3-(N-hydroxyformamido)propyl)phosphonic acid, 1] and its acetyl homologue FR-900098 [(3-(N-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4976127b2d93a7de369d9f8502771261
https://biblio.ugent.be/publication/8509194/file/8509199
https://biblio.ugent.be/publication/8509194/file/8509199
Publikováno v:
FEBS Journal. 276:2116-2124
Periplasmic binding proteins are abundant in bacteria by virtue of their essential roles as high-affinity receptors in ABC transport systems and chemotaxis. One of the best studied of these receptors is the so-called glucose/galactose-binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4789d2fa13568ba46b114586088e42a2
https://doi.org/10.1111/j.1742-4658.2009.06945.x
https://doi.org/10.1111/j.1742-4658.2009.06945.x
Autor:
Mee-Len Chye, Julian A. Tanner, Qin-Fang Chen, Sherry L. Mowbray, Pan Liao, Louise V. Michaelson, Richard P. Haslam, Johnathan A. Napier, An‑Shan Hsiao, Sanjeewani Sooriyaarachchi
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 34, Iss 6, p e00165 (2014)
Bioscience Reports, Vol 34, Iss 6, p e00165 (2014)
Eukaryotic cytosolic ACBPs (acyl-CoA-binding proteins) bind acyl-CoA esters and maintain a cytosolic acyl-CoA pool, but the thermodynamics of their protein–lipid interactions and physiological relevance in plants are not well understood. Arabidopsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ff5d8051f261b7170282c5c646c26b
http://hdl.handle.net/10722/209287
http://hdl.handle.net/10722/209287
Autor:
Mounir Andaloussi, Mats Larhed, C. Bjorkelid, Terese Bergfors, Anna M. Jansson, Sherry L. Mowbray, Samir Yahiaoui, Sanjeewani Sooriyaarachchi, Rautela Nikhil, Sharma Sreevalli, Bachally R. Srinivasa, Surisetti Suresh, Shyamraj Dharavath, Anna Więckowska, T. Alwyn Jones, Martin Lindh, Matthieu Desroses, Anders Karlén
Publikováno v:
Journal of medicinal chemistry. 56(15)
The antimalarial compound fosmidomycin targets DXR, the enzyme that catalyzes the first committed step in the MEP pathway producing the universally essential isoprenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate. The MEP pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2c77bbd5da0945f62c21dfbd865e88
https://pubmed.ncbi.nlm.nih.gov/23819803
https://pubmed.ncbi.nlm.nih.gov/23819803
Autor:
Wimal Ubhayasekera, Sanjeewani Sooriyaarachchi, Sherry L. Mowbray, Fred O. Asiegbu, Adrian Suarez Covarrubias
Publikováno v:
Science and Technology Against Microbial Pathogens.
1 Department of Molecular Biology, Swedish University of Agricultural Sciences, Box 590, Biomedical Center, SE-751 24, Uppsala, Sweden 2 Department of Cell and Molecular Biology, Uppsala University, Box 596, Biomedical Center, SE-751 24, Uppsala, Swe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ba92e0e13c495fde10f1f386fe2626
https://doi.org/10.1142/9789814354868_0001
https://doi.org/10.1142/9789814354868_0001
Autor:
Wimal Ubhayasekera, Sherry L. Mowbray, Fred O. Asiegbu, Adrian Suarez Covarrubias, Emad Jaber, Sanjeewani Sooriyaarachchi
Publikováno v:
Plant molecular biology. 77(1-2)
Scots pine (Pinus sylvestris) secretes a number of small, highly-related, disulfide-rich proteins (Sp-AMPs) in response to challenges with fungal pathogens such as Heterobasidion annosum, although their biological role has been unknown. Here, we exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efcce8041464f9cb78ed5f18d1eb628
https://pubmed.ncbi.nlm.nih.gov/21584858
https://pubmed.ncbi.nlm.nih.gov/21584858
ATP binding cassette transport systems account for most import of necessary nutrients in bacteria. The periplasmic binding component (or an equivalent membrane-anchored protein) is critical to recognizing cognate ligand and directing it to the approp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c372b41028c8e55e696fdc20a5ebee6a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-142155
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-142155