Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sanjeevkumar R, Patel"'
Autor:
Ryan S, Hsi, Autumn N, Valicevic, Sanjeevkumar R, Patel, Mary K, Oerline, Alan C, Pao, John T, Leppert, John M, Hollingsworth, Vahakn, Shahinian
Publikováno v:
Urol Pract
PURPOSE: Recent observational studies reporting a lack of benefit from 24-hour urine testing for urinary stone disease (USD) prevention assumed testing included all components recommended from clinical guidelines. We sought to assess the completeness
Autor:
Rakesh Verma, Madhusudan Venkatareddy, Anne Kalinowski, Theodore Li, Joanna Kukla, Ashomathi Mollin, Gabriel Cara-Fuentes, Sanjeevkumar R Patel, Puneet Garg
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198013 (2018)
Nephrin (Nphs1) is an adhesion protein that is expressed at the podocyte intercellular junction in the glomerulus. Nphs1 mutations in humans or deletion in animal genetic models results in a developmental failure of foot process formation. A number o
Externí odkaz:
https://doaj.org/article/c7501deab3ef457286401f35ee7366c5
Autor:
Toby W. Hurd, Puneet Garg, Danny Luan, Sanjeevkumar R. Patel, Madhusudan Venkatareddy, Markus Bitzer, Saji Abraham, Raghavendra Paknikar, Christopher L. O’Connor, Samina Bhumbra, Robert A. Fenton
Publikováno v:
Abraham, S, Paknikar, R, Bhumbra, S, Luan, D, Venkatareddy, M, O'Connor, C, Bitzer, M, Fenton, R A, Hurd, T, Garg, P & Patel, S R 2021, ' Epigenetic regulation of arginine vasopressin receptor 2 expression by PAX2 and Pax transcription interacting protein ', American journal of physiology. Renal physiology, vol. 320, no. 3, pp. F404-F417 . https://doi.org/10.1152/ajprenal.00371.2020
Am J Physiol Renal Physiol
Am J Physiol Renal Physiol
Renal arginine vasopressin receptor 2 (AVPR2) plays a crucial role in osmoregulation. Engagement of ligand with AVPR2 results in aquaporin 2 movement to the apical membrane and water reabsorption from the urinary filtrate. Despite this essential role
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148906 (2016)
Nephrin is expressed at the basolateral aspect of podocytes and is an important signaling protein at the glomerular slit diaphragm. In vitro studies have demonstrated that Nephrin phosphorylation-dependent signaling is able to assemble a protein comp
Externí odkaz:
https://doaj.org/article/79723b64a62242fd9889f50b31d5dcb6
Autor:
Shayna T.J. Bradford, Pil H. Lee, Ann M. Laszczyk, Edward Grimley, Sanjeevkumar R. Patel, Gregory R. Dressler
Publikováno v:
Cell Chem Biol
The Pax family of developmental control genes are frequently deregulated in human disease. In the kidney, Pax2 is expressed in developing nephrons but not in adult proximal and distal tubules, whereas polycystic kidney epithelia or renal cell carcino
Autor:
Craig N. Johnson, Atsuko Y. Higashi, Abdul Soofi, Sanjeevkumar R. Patel, Gregory R. Dressler, Saji Abraham, Ann M. Laszczyk
Publikováno v:
J Am Soc Nephrol
Background As the glomerular filtrate passes through the nephron and into the renal medulla, electrolytes, water, and urea are reabsorbed through the concerted actions of solute carrier channels and aquaporins at various positions along the nephron a
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001142 (2010)
Methylation of specific lysine residues in core histone proteins is essential for embryonic development and can impart active and inactive epigenetic marks on chromatin domains. The ubiquitous nuclear protein PTIP is encoded by the Paxip1 gene and is
Externí odkaz:
https://doaj.org/article/35137249ee834f428ce12e91b0779f53
Autor:
Rohan Garg, Sanjeevkumar R. Patel, Gregory R. Dressler, Danny Luan, Raghavendra Paknikar, Samina Bhumbra, Saji Abraham
Publikováno v:
Journal of Biological Chemistry. 290:7185-7194
Pax genes encode developmental regulatory proteins that specify cell lineages and tissues in metazoans. Upon binding to DNA through the conserved paired domain, Pax proteins can recruit both activating and repressing complexes that imprint distinct p
Publikováno v:
Pediatric Nephrology. 29:589-595
During embryonic development, DNA binding proteins help specify and restrict the fates of pluripotent stem cells. In the developing kidney, Pax2 proteins are among the earliest markers for the renal epithelial cell lineage, with expression in the mes
Autor:
Puneet Garg, Rakesh Verma, Sanjeevkumar R. Patel, Madhusudan Venkatareddy, David J. Salant, Anne Kalinowski
In most forms of glomerular diseases, loss of size selectivity by the kidney filtration barrier is associated with changes in the morphology of podocytes. The kidney filtration barrier is comprised of the endothelial lining, the glomerular basement m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f7ff29275df70321a1f10a4a8143e8
https://europepmc.org/articles/PMC4751697/
https://europepmc.org/articles/PMC4751697/