Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sanjaya C. Abeysirigunawarden"'
Autor:
Sudeshi M. Abedeera, Kumudie S. Jayalath, Jiale Xie, Rushdhi M. Rauff, Sanjaya C. Abeysirigunawardena
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1447 (2023)
Bacterial ribosome small subunit rRNA (16S rRNA) contains 11 nucleotide modifications scattered throughout all its domains. The 16S rRNA pseudouridylation enzyme, RsuA, which modifies U516, is a survival protein essential for bacterial survival under
Externí odkaz:
https://doaj.org/article/38cb127d44f542c49d70c409a87a2e3e
Autor:
Sanjaya C. Abeysirigunawardena, Hajin Kim, Jonathan Lai, Kaushik Ragunathan, Mollie C. Rappé, Zaida Luthey-Schulten, Taekjip Ha, Sarah A. Woodson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′
Externí odkaz:
https://doaj.org/article/f192a5c8e0dd4953a26b536e8ef4f6f9
Autor:
Zaida Luthey-Schulten, Kaushik Ragunathan, Taekjip Ha, Megan Mayerle, Hajin Kim, Ke Chen, Sanjaya C. Abeysirigunawarden, Sarah A. Woodson
Publikováno v:
Nature. 506:334-338
The assembly of 30S ribosomes requires the precise addition of 20 proteins to the 16S ribosomal RNA. How early binding proteins change the ribosomal RNA structure so that later proteins may join the complex is poorly understood. Here we use single-mo