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Involvement of the PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora

Autor: Sanjay Vir, Florian Lang, Mamta B. Shah, Kamlesh K. Bhutani, Dev D. Santani, Shefalee K. Bhavsar, Michael Föller, Shuchen Gu

Publikováno v: Journal of Ethnopharmacology. 126:386-396

Aim of the study Saponins from Helicteres isora have previously been shown to exert antidiabetic effects. The present study explored the underlying mechanisms in C2C12 skeletal muscle cells. Materials and methods C2C12 cells were incubated with sapon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e6a58376d188aec4fb5d5f305cd19b
https://doi.org/10.1016/j.jep.2009.09.027

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Liquid chromatography–mass spectrometry-based quantification of steroidal glycoalkaloids from Solanum xanthocarpum and effect of different extraction methods on their content

Autor: Kamlesh K. Bhutani, Sanjay Vir, Atish T. Paul

Publikováno v: Journal of Chromatography A. 1208:141-146

A new liquid chromatography–mass spectrometry (LC–MS)-based method coupled with pressurized liquid extraction (PLE) as an efficient sample preparation technique has been developed for the quantification and fingerprint analysis of Solanum xanthoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd0ea94988e479d90ffe0a035db0dac
https://doi.org/10.1016/j.chroma.2008.08.089

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Quantitative Analysis of Various B-ring Unsubstituted and Substituted Flavonoids in Ten Australian Species of Eucalyptus

Autor: Inder Pal Singh, William J. Foley, Sanjay Vir, Isha Saraf, Karen J. Marsh

Publikováno v: Natural Product Communications. 12:1934578X1701201

Flavonoids (in particular unsubstituted B ring flavanones) in Eucalyptus foliage play an important role in mediating animal plant interactions, and there is a need for methods to analyse the diverse profiles found in leaves. A simple, high-performanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4777775b5f5e33a4f1571b17ced0aff3
https://doi.org/10.1177/1934578x1701201109

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Microbial Community Structure at Different Fermentation Stages of Kutajarista, a Herbal Formulation

Autor: Himanshu Kumar, Yogesh S. Shouche, Milind S. Patole, V. V. Doiphode, Sanjay Vir, Kamlesh K. Bhutani, Prashant Kumar Pandey

Kutajarista is an Ayurvedic fermented herbal formulation prescribed for gastrointestinal disorders. This herbal formulation undergoes a gradual fermentative process and takes around 2 months for production. In this study, microbial composition at ini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b43631616406dccecc12f6ac88f785
https://europepmc.org/articles/PMC3587512/

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LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method

Autor: Raj Kumar, Asit K. Chakraborti, K.C. Jindal, Saranjit Singh, Sanjay Vir, Hemant Bhutani, Kamlesh K. Bhutani

Publikováno v: Journal of pharmaceutical and biomedical analysis. 43(4)

Isoniazid was subjected to different ICH prescribed stress conditions of thermal stress, hydrolysis, oxidation and photolysis. The drug was stable to dry heat (50 and 60 degrees C). It showed extensive decomposition under hydrolytic conditions, while

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afb7dd3e806f864264165cc77d8be84
https://pubmed.ncbi.nlm.nih.gov/17118610

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