Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sanjay S. Aripaka"'
Autor:
Burcu A. Pazarlar, Sanjay S. Aripaka, Viktor Petukhov, Lars Pinborg, Konstantin Khodosevich, Jens D. Mikkelsen
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Synaptic vesicle glycoprotein-2 (SV2) is a family of proteins consisting of SV2A, SV2B, and SV2C. This protein family has attracted attention in recent years after SV2A was shown to be an epileptic drug target and a perhaps a biomarker of sy
Externí odkaz:
https://doaj.org/article/9ca4e0bee90e442c8e3349b0385ee878
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 100872- (2022)
Introduction: Increased catabolism of the extracellular matrix is observed under degenerative disc disease (DDD). The cleavage of extracellular matrix proteins in the nucleus pulposus (NP) by either matrix metalloproteinases (MMPs) or a disintegrin a
Externí odkaz:
https://doaj.org/article/ec76386c423340f1ba9b361089ce9120
Autor:
Jens D. Mikkelsen, Sanjay S. Aripaka, Sif Kaad, Burcu A. Pazarlar, Lars Pinborg, Bente Finsen, Andrea Varrone, Benny Bang-Andersen, Jesper F. Bastlund
Publikováno v:
ACS Chemical Neuroscience. 14:111-118
Autor:
Jens D, Mikkelsen, Sanjay S, Aripaka, Pablo, Bascuñana, Marion, Bankstahl, Jens P, Bankstahl, Burcu A, Pazarlar
Publikováno v:
Mikkelsen, J D, Aripaka, S S, Bascuñana, P, Bankstahl, M, Bankstahl, J P & Pazarlar, B A 2022, ' Spatio-Temporal Alterations in Synaptic Density During Epileptogenesis in the Rat Brain ', Neuroscience, vol. 499, pp. 142-151 . https://doi.org/10.1016/j.neuroscience.2022.07.020
Synaptic vesicle glycoprotein 2A (SV2A) is a transmembrane protein that binds levetiracetam and is involved in neurotransmission via an unknown mechanism. SV2A-immunoreactivity is reduced in animal models of epilepsy, and in postmortem hippocampi fro
Publikováno v:
Molecular and Cellular Biochemistry. 478:121-130
Autor:
Osama I. Alwassil, Marvin K. Schulte, Sanjay S Aripaka, Malgorzata Dukat, Jens D. Mikkelsen, Shailesh Khatri
Publikováno v:
ACS Chemical Neuroscience. 12:2194-2201
We previously reported that N-(3-chlorophenyl)guanidine (1) represents a novel α7 nicotinic ACh (nACh) receptor antagonist chemotype. In the present study, a small series of compounds was synthesized with the intent to investigate the structure-acti
Autor:
Jens D. Mikkelsen, Sanjay S Aripaka, T Bendix, S A Chughtai, R Bech-Azeddine, Louise Møller Jørgensen, C Gaarde
Publikováno v:
European Spine Journal. 30:2967-2974
The molecular mechanism behind pain in degenerative disc disease (DDD) and chronic low back pain (LBP) patients is largely unknown. This present study examines the association of LBP and disability to mediators of the inflammatory cascade, as indexed
Publikováno v:
SSRN Electronic Journal.
Autor:
Burcu A. Pazarlar, Sanjay S. Aripaka, Viktor Petukhov, Lars Pinborg, Konstantin Khodosevich, Jens D. Mikkelsen
Publikováno v:
Pazarlar, B A, Aripaka, S S, Petukhov, V, Pinborg, L, Khodosevich, K & Mikkelsen, J D 2022, ' Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE) ', Molecular Brain, vol. 15, no. 1, 45 . https://doi.org/10.1186/s13041-022-00931-w
Synaptic vesicle glycoprotein-2 (SV2) is a family of proteins consisting of SV2A, SV2B, and SV2C. This protein family has attracted attention in recent years after SV2A was shown to be an epileptic drug target and a perhaps a biomarker of synaptic de
Publikováno v:
Aripaka, S S, Bech-Azeddine, R, Jørgensen, L M & Mikkelsen, J D 2022, ' The expression of metalloproteinases in the lumbar disc correlates strongly with Pfirrmann MRI grades in lumbar spinal fusion patients ', Brain and Spine, vol. 2, 100872 . https://doi.org/10.1016/j.bas.2022.100872
Brain and Spine, Vol 2, Iss, Pp 100872-(2022)
Brain and Spine, Vol 2, Iss, Pp 100872-(2022)
Introduction: Increased catabolism of the extracellular matrix is observed under degenerative disc disease (DDD). The cleavage of extracellular matrix proteins in the nucleus pulposus (NP) by either matrix metalloproteinases (MMPs) or a disintegrin a