N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells.

Autor: Ramesh B Badisa, Sanjay S Kumar, Elizabeth Mazzio, Rasheda D Haughbrook, John R Allen, Michael W Davidson, Cheryl A Fitch-Pye, Carl B Goodman

Publikováno v: PLoS ONE, Vol 10, Iss 1, p e0114285 (2015)

Cocaine has a short half-life of only about an hour but its effects, predominantly on the central nervous system (CNS), are fairly long-lasting. Of all cells within the CNS, astrocytes may be the first to display cocaine toxicity owing to their relat

Externí odkaz: https://doaj.org/article/1779d78db14c406dbb7059a0ebbdbd85

The GluN3 subunit regulates ion selectivity within native N-methyl-d-aspartate receptors

Autor: Stephen Beesley, Thomas Sullenberger, Sanjay S. Kumar

Publikováno v: IBRO Reports, Vol 9, Iss , Pp 147-156 (2020)

Glutamatergic N-methyl-d-aspartate receptors (NMDARs) are heterotetrameric proteins whose subunits are derived from three gene families, GRIN1 (codes for GluN1), GRIN2 (GluN2) and GRIN3 (GluN3). In addition to providing binding sites for glutamate an

Externí odkaz: https://doaj.org/article/c9991b797a1c45fcb89920a6facb1361

Discontinuous conduction mode of a three-level boost DC-DC converter and its merits and limits for voltage cross regulation applications

Autor: Lais A. Vitoi, Deepak Elamalayil Soman, Mats Leijon, Remya Krishna, Kasthuri Vikram, Janaina Goncalves de Oliveira, Sasi K. Kottayil, Sanjay S. Kumar

Publikováno v: IECON

Distributed generation and smart grid integration of renewable energy sources introduce a lot of challenges for the enabling power electronic converter technology. Some of these challenges include wide controllability range, high power handling and g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c3d38914bff87753cb07267e5a3d948
https://doi.org/10.1109/iecon.2014.7049144

Contributing Authors

Autor: Massimo Avoli, Roy A. Bakay, Scott C. Baraban, Tallie Z. Baram, Stefania Bassanini, Giorgio Battaglia, Christophe Bernard, Edward H. Bertram, Ronald A. Browning, Paul S. Buckmaster, Daniel L. Burgess, Thomas Budde, Xiang Cai, Esper A. Cavalheiro, Wei-Ping Chen, Suzanne Clark, Miguel A. Cortez, Marco de Curtis, Antoine Depaulis, Marc A. Dichter, Céline Dinocourt, Céliné M. Dubé, F. Edward Dudek, Jerome Engel, Aristea S. Galanopoulou, Mary E. Gilbert, Jeffrey H. Goodman, Ali Gorji, Heidi Grabenstatter, Kevin D. Graber, Uwe Heinemann, Gregory L. Holmes, John R. Huguenard, John G.R. Jefferys, Frances E. Jensen, Phillip C. Jobe, Oliver Kann, Kevin M. Kelly, Irina Kharatishvilli, Rüdiger Köhling, Hana Kubová, Sanjay S. Kumar, João P. Leite, Laura Librizzi, Dean D. Lin, Wolfgang Löscher, Joseph J. LoTurco, Heiko J. Luhmann, Gilles van Luijtelaar, Pavel Mareš, Gary W. Mathern, Andrey M. Mazarati, Tracy K. McIntosh, Dan C. McIntyre, James O. McNamara, Luiz E. Mello, Solomon L. Moshé, Maria G. Naffah-Mazzacoratti, Astrid Nehlig, Prosper N'Gouemo, Jari Nissinen, Jeffrey L. Noebels, Michael W. Nestor, Andre Obenaus, Jeffrey Ockuly, Hans-Christian Pape, Asla Pitkänen, John Pollard, David A. Prince, Dominick P. Purpura, Raddy L. Ramos, Charles E. Ribak, Michael A. Rogawski, Steven N. Roper, Russell M. Sanchez, Raman Sankar, Sebastian Schuchmann, Philip A. Schwartzkroin, Laszlo Seress, Lee A. Shapiro, Yukiyoshi Shirasaka, Margaret N. Shouse, Misty Smith-Yockman, O. Carter Snead, Erwin-Josef Speckmann, Ajay Srivastava, Carl E. Stafstrom, Mark Stewart, Janet L. Stringer, Lucie Suchomelova, Thomas P. Sutula, Kerry W. Thompson, Scott M. Thompson, William J. Triggs, Yuto Ueda, Laura Uva, Libor Velíšek, Jana Velíšková, Matthew C. Walker, Claude Wasterlain, H. Jürgen Wenzel, H. Steve White, Karen S. Wilcox, Philip A. Williams, L. James Willmore, Robert K.S. Wong, Qian Zhao

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a1bf51ca9405ffda1a79fa1d26788db
https://doi.org/10.1016/b978-012088554-1/50000-1

D-serine mitigates cell loss associated with temporal lobe epilepsy

Autor: Stephen Beesley, Thomas Sullenberger, Kathryn Crotty, Roshan Ailani, Cameron D’Orio, Kimberly Evans, Emmanuel O. Ogunkunle, Michael G. Roper, Sanjay S. Kumar

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Temporal lobe epilepsy (TLE) can be unresponsive to treatment. Here, the authors show that treatment with D-Serine mitigates TLE and acts on neurons and glia, attenuating neuronal loss and reducing astro- and microgliosis in rodents.

Externí odkaz: https://doaj.org/article/251e82a043a74a02a6ee2fbc9ddc2d09