Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sanjay Kansra"'
Autor:
Santhi D. Konduri, Madhavi Latha Yadav Bangaru, Phu Thanh Do, Shenglin Chen, Jeffrey Woodliff, Sanjay Kansra
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 2, Iss 4, Pp 156-164 (2015)
Purpose: Malignant clear cell renal carcinoma (ccRCC) is an aggressive tumor highly resistant to chemotherapy and radiation. Current therapeutic approaches to management of ccRCC have not significantly improved patient survival, therefore novel thera
Externí odkaz:
https://doaj.org/article/d39d0b49be6649e99e713da4efbe4149
Autor:
Stefan W. Stoll, Sanjay Kansra, Scott Peshick, David W. Fry, Wilbur R. Leopold, Jane F. Wiesen, Maria Sibilia, Tong Zhang, Zena Werb, Rik Derynck, Erwin F. Wagner, James T. Elder
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 4, Pp 339-350 (2001)
Induction of heparin-binding epidermal growth factorlike growth factor (HB-EGF) mRNA in mouse skin organ culture was blocked by two pan-ErbB receptor tyrosine kinase (RTK) inhibitors but not by genetic ablation of ErbB1, suggesting involvement of mul
Externí odkaz:
https://doaj.org/article/753b197d6461405099efe365bea4b63c
Autor:
Sanjay Kansra, Shenglin Chen, Madhavi Latha Yadav Bangaru, Leighton Sneade, Joseph A Dunckley, Nira Ben-Jonathan
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10060 (2010)
We recently reported that estrogen receptor alpha (ERalpha), even in absence of estrogen (E2), plays a critical role in lactotroph homeostasis. The anti-estrogen ICI 182780 (ICI), but not tamoxifen or raloxifene, rapidly promoted the degradation of E
Externí odkaz:
https://doaj.org/article/5a5667a3ddc5431fb5ce40538e290f79
Publikováno v:
PLoS ONE, Vol 5, Iss 4 (2010)
Externí odkaz:
https://doaj.org/article/b4bf048e3b1243b7859432cab1ef9ae9
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9893 (2010)
BACKGROUND: Pituitary corticotroph tumors secrete excess adrenocorticotrophic hormone (ACTH) resulting in Cushing's disease (CD). Standard treatment includes surgery and, if not successful, radiotherapy, both of which have undesirable side effects an
Externí odkaz:
https://doaj.org/article/dabf502ba6ef4528a2747a4ce38b4432
Autor:
Phu Thanh Do, Shenglin Chen, Sanjay Kansra, Madhavi Latha Yadav Bangaru, Jeffrey Woodliff, Santhi D. Konduri
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 2, Iss 4, Pp 156-164 (2015)
Purpose: Malignant clear cell renal carcinoma (ccRCC) is an aggressive tumor highly resistant to chemotherapy and radiation. Current therapeutic approaches to management of ccRCC have not significantly improved patient survival, therefore novel thera
Autor:
Timothy M. Johnson, Laure Rittié, Yuan Shao, Lowell Evan Michael, Yong Li, Gary J. Fisher, Johann E. Gudjonsson, Sanjay Kansra, James T. Elder, Stefan W. Stoll
Publikováno v:
The American Journal of Pathology. 170:2089-2099
In this study, we examined ErbB1 signaling in human basal and squamous cell carcinomas (BCC and SCC) of the skin in vivo. We used enzyme-linked immunosorbent assay, laser capture microdissection-coupled real-time reverse transcriptase-polymerase chai
Publikováno v:
Molecular Biology of the Cell. 15:4299-4309
ErbB signaling through extracellular signal-regulated kinase (ERK) has been implicated in regulating the expression of ErbB ligands in hyperproliferative skin disorders and wound healing. Here, we characterize the process of autocrine ERK activation
Publikováno v:
Wound Repair and Regeneration. 11:346-353
Organ culture of skin is known to recapitulate several early events in the process of wound healing. Here we investigate the function of p38 kinase signaling as a regulator of keratinocyte behavior in human skin organ culture. We first show that skin
Autor:
Jeffrey E. Edwards, Yuanyuan Zhang, Jonathan P. Jackson, Kenneth R. Brouwer, Carl LaCerte, Sanjay Kansra
Publikováno v:
Pharmacology Research & Perspectives
Obeticholic acid (OCA) is a semisynthetic farnesoid X receptor (FXR) agonist, an analogue of chenodeoxycholic acid (CDCA) which is indicated for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA). OCA e