Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Sanjay B. Maggirwar"'
Autor:
Meera V. Singh, Md Nasir Uddin, Mae Covacevich Vidalle, Karli R. Sutton, Zachary D. Boodoo, Angelique N. Peterson, Alicia Tyrell, Madalina E. Tivarus, Henry Z. Wang, Bogachan Sahin, Jianhui Zhong, Miriam T. Weber, Lu Wang, Xing Qiu, Sanjay B. Maggirwar, Giovanni Schifitto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundDespite antiretroviral treatment (cART), aging people living with HIV (PWH) are more susceptible to neurocognitive impairment (NCI) probably due to synergistic/additive contribution of traditional cerebrovascular risk factors. Specifically,
Externí odkaz:
https://doaj.org/article/966b402f354c448595e8a92f0ba94bfe
Autor:
Kaitlin Garofano, Kameron Rashid, Michael Smith, Christine Brantner, Sumanun Suwunnakorn, David Diemert, Olivia Gordon, Anelia Horvath, Sikandar Khan, Anastas Popratiloff, Johng Rhim, Alfateh Sidahmed, Sanjay B. Maggirwar, Travis J. O’Brien, Minoli A. Perera, Norman H. Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Platelets play a crucial role in cancer and thrombosis. However, the receptor-ligand repertoire mediating prostate cancer (PCa) cell-platelet interactions and ensuing consequences have not been fully elucidated. Microvilli emanating from the
Externí odkaz:
https://doaj.org/article/8d0b641d98c845a78be8abe3c23d4390
Autor:
Adam Cornwell, Rohith Palli, Meera V. Singh, Lauren Benoodt, Alicia Tyrell, Jun-ichi Abe, Giovanni Schifitto, Sanjay B. Maggirwar, Juilee Thakar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract People living with HIV are at higher risk of atherosclerosis (AS). The pathogenesis of this risk is not fully understood. To assess the regulatory networks involved in AS we sequenced mRNA of the peripheral blood mononuclear cells (PBMCs) an
Externí odkaz:
https://doaj.org/article/50c82d93ef8840fd8ec8d9ebf2e6750a
Autor:
Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H. Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L. Schadler, Caroline Chung, Sarah A. Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N. Amaya, Huifang Guo, Tamlyn N. Thomas, Ying H. Shen, Anita Deswal, Joerg Herrmann, Eugenie S. Kleinerman, Mark L. Entman, John P. Cooke, Giovanni Schifitto, Sanjay B. Maggirwar, Elena McBeath, Anisha A. Gupte, Sunil Krishnan, Zarana S. Patel, Yisang Yoon, Jared K. Burks, Keigi Fujiwara, Paul S. Brookes, Nhat-Tu Le, Dale J. Hamilton, Jun-ichi Abe
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102132- (2021)
The incidence of cardiovascular disease (CVD) is higher in cancer survivors than in the general population. Several cancer treatments are recognized as risk factors for CVD, but specific therapies are unavailable. Many cancer treatments activate shar
Externí odkaz:
https://doaj.org/article/e0a94c31b512406eaddff3363f57a4c3
Publikováno v:
Pathogens, Vol 11, Iss 6, p 611 (2022)
The use of antiretroviral therapy (ART) for Human Immunodeficiency Virus (HIV) treatment has been highly successful in controlling plasma viremia to undetectable levels. However, a complete cure for HIV is hindered by the presence of replication-comp
Externí odkaz:
https://doaj.org/article/c8467434dc3e484aa4f387a7efbde2fb
Autor:
Kyle D. Murray, Md Nasir Uddin, Madalina E. Tivarus, Bogachan Sahin, Henry Z. Wang, Meera V. Singh, Xing Qiu, Lu Wang, Pascal Spincemaille, Yi Wang, Sanjay B. Maggirwar, Jianhui Zhong, Giovanni Schifitto
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102786- (2021)
The aim of this study was to assess, in the context of cerebral small vessel disease (CSVD), whether cardiovascular risk factors and white matter hyperintensities (WMHs) were associated with brain tissue susceptibility as measured by quantitative sus
Externí odkaz:
https://doaj.org/article/79807b13a428435d86b533eb16f676c7
Autor:
Kyle D. Murray, Meera V. Singh, Yuchuan Zhuang, Md Nasir Uddin, Xing Qiu, Miriam T. Weber, Madalina E. Tivarus, Henry Z. Wang, Bogachan Sahin, Jianhui Zhong, Sanjay B. Maggirwar, Giovanni Schifitto
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Rationale: We provide an in-depth description of a comprehensive clinical, immunological, and neuroimaging study that includes a full image processing pipeline. This approach, although implemented in HIV infected individuals, can be used in the gener
Externí odkaz:
https://doaj.org/article/666ea52b702e47338d29c9d84ccf95ce
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2321 (2022)
Platelets, which are small anuclear cell fragments, play important roles in thrombosis and hemostasis, but also actively release factors that can both suppress and induce viral infections. Platelet-released factors include sCD40L, microvesicles (MVs)
Externí odkaz:
https://doaj.org/article/a10ee14109984b86abfd33ccb4d98f70
Autor:
Emily A. Weber, Meera V. Singh, Vir B. Singh, Joseph W. Jackson, Sara K. Ture, Sumanun Suwunnakorn, Craig N. Morrell, Sanjay B. Maggirwar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)
Background Microvesicles are cell membrane–derived vesicles that have been shown to augment inflammation. Specifically, monocyte‐derived microvesicles (MDMVs), which can express the coagulation protein tissue factor, contribute to thrombus format
Externí odkaz:
https://doaj.org/article/72cf705b06c24b648bf055402bed22c9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The major barrier to HIV cure is a population of long-lived cells that harbor latent but replication-competent virus, are not eliminated by antiretroviral therapy (ART), and remain indistinguishable from uninfected cells. However, ART does not cure H
Externí odkaz:
https://doaj.org/article/3cd870667287443497cc6cbda097a026