Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sanjarbek Hudaiberdiev"'
Publikováno v:
eLife, Vol 13 (2024)
Enhancers and promoters are classically considered to be bound by a small set of transcription factors (TFs) in a sequence-specific manner. This assumption has come under increasing skepticism as the datasets of ChIP-seq assays of TFs have expanded.
Externí odkaz:
https://doaj.org/article/104d7a6271ac42d4949d0a35b2a19b50
Autor:
Sanjarbek Hudaiberdiev, Sergey Shmakov, Yuri I. Wolf, Michael P. Terns, Kira S. Makarova, Eugene V. Koonin
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background The Cas4 family endonuclease is a component of the adaptation module in many variants of CRISPR-Cas adaptive immunity systems. Unlike most of the other Cas proteins, Cas4 is often encoded outside CRISPR-cas loci (solo-Cas4) and is
Externí odkaz:
https://doaj.org/article/4c28588f55d44954ab98dff352611948
Autor:
Sándor Pongor, Vittorio Venturi, Borisz Galbáts, Zsolt Gelencsér, Kumari Sonal Choudhary, Bruna Goncalves Coutinho, Sanjarbek Hudaiberdiev
Publikováno v:
Sensors, Vol 12, Iss 5, Pp 5432-5444 (2012)
Virulence and adaptability of many Gram-negative bacterial species are associated with an N-acylhomoserine lactone (AHL) gene regulation mechanism called quorum sensing (QS). The arrangement of quorum sensing genes is variable throughout bacterial ge
Externí odkaz:
https://doaj.org/article/1fcb05c4020d4907b9bacc625e2ba509
Autor:
Iztok Dogsa, Kumari Sonal Choudhary, Ziva Marsetic, Sanjarbek Hudaiberdiev, Roberto Vera, Sándor Pongor, Ines Mandic-Mulec
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96122 (2014)
The comQXPA locus of Bacillus subtilis encodes a quorum sensing (QS) system typical of Gram positive bacteria. It encodes four proteins, the ComQ isoprenyl transferase, the ComX pre-peptide signal, the ComP histidine kinase, and the ComA response reg
Externí odkaz:
https://doaj.org/article/868064eea87443468bb4b5a407d2e473
Publikováno v:
bioRxiv
Bioinformatics
Bioinformatics
MotivationPredicting the regulatory function of non-coding DNA using only the DNA sequence continues to be a major challenge in genomics. With the advent of improved optimization algorithms, faster GPU speeds, and more intricate machine learning libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb34963b84be0f291fbfb018ced33c
https://europepmc.org/articles/PMC9928050/
https://europepmc.org/articles/PMC9928050/
Autor:
SANJARBEK HUDAIBERDIEV
Genetic association studies have identified hundreds of independent signals associated with type 2 diabetes (T2D) and related traits. Despite these successes, the identification of specific causal variants underlying a genetic association signal rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b61475209b9218ab63a1568ead94014
https://doi.org/10.1101/2022.05.13.22275035
https://doi.org/10.1101/2022.05.13.22275035
Autor:
Riana D. Hunter, Nolwenn Jean-Marçais, Brigitte Gilbert-Dussardier, Catherine S. Novak, Tyler H. Garvin, Matthew B. Dobbs, Len A. Pennacchio, Stella Tran, Yiwen Zhu, Florence Petit, Eman Meky, Axel Visel, Ivan Ovcharenko, Momoe Kato, Jennifer A. Akiyama, Diane E. Dickel, Christina A. Gurnett, Fabienne Escande, Quan Pham, Sylvie Manouvrier-Hanu, Janeth Godoy, Evgeny Z. Kvon, Sanjarbek Hudaiberdiev, Ingrid Plajzer-Frick, Guy Kelman, Veena Afzal, Anne N. Harrington
Publikováno v:
Cell
Establishing causal links between non-coding variants and human phenotypes is an increasing challenge. Here, we introduce a high-throughput mouse reporter assay for assessing the pathogenic potential of human enhancer variants in vivo and examine nea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6bba4a3022ae0afd5dcda5986787e8
https://doi.org/10.1016/j.cell.2020.02.031
https://doi.org/10.1016/j.cell.2020.02.031
Autor:
Michael P. Terns, Sanjarbek Hudaiberdiev, Sergey Shmakov, Eugene V. Koonin, Kira S. Makarova, Yuri I. Wolf
Publikováno v:
BMC Evolutionary Biology
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-14 (2017)
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-14 (2017)
Background The Cas4 family endonuclease is a component of the adaptation module in many variants of CRISPR-Cas adaptive immunity systems. Unlike most of the other Cas proteins, Cas4 is often encoded outside CRISPR-cas loci (solo-Cas4) and is also fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988806433adf1601cec50c558012559b
https://pubmed.ncbi.nlm.nih.gov/29179671
https://pubmed.ncbi.nlm.nih.gov/29179671
Autor:
Zsolt Gelencser, Sanjarbek Hudaiberdiev, Kumari Sonal Choudhary, Vittorio Venturi, Bruna G. Coutinho, Sándor Pongor
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13727-13747 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 7; Pages: 13727-13747
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 7; Pages: 13727-13747
Members of the Burkholderia genus of Proteobacteria are capable of living freely in the environment and can also colonize human, animal and plant hosts. Certain members are considered to be clinically important from both medical and veterinary perspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93464f3503fb4f0f6018dcf861de671b
http://www.mdpi.com/1422-0067/14/7/13727
http://www.mdpi.com/1422-0067/14/7/13727
Autor:
Sanjarbek Hudaiberdiev, Shmakov, Sergey, Wolf, Yuri, Terns, Michael, Makarova, Kira, Koonin, Eugene
Nucleotide sequence comparisons of CRISPR-Cas loci encoded in closely related strains. On the axes, the labels contain the name of the source genome, contig ID and the coordinates of the respective loci. The annotations for CRISPR-Cas loci were taken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187fd8b3727e72d987652906f777d93c