Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sanjana Surya Prakash"'
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103358- (2024)
Summary: Surface availability of the dopamine (DA) transporter (DAT) critically influences DA transmission. Here, we present a protocol that describes the preparation of mouse ventral midbrain neurons, the expression of a new optical sensor, DAT-pHlu
Externí odkaz:
https://doaj.org/article/963453784d444760acddee61f96e93b1
A major pathological hallmark of Parkinson’s Disease (PD) is the manifestation of Lewy bodies comprised of alpha-synuclein (α-syn). The accumulation of α-syn enriched protein aggregates is thought to arise from dysfunction in degradation systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4072a78657e2035e907fbeb0924854
https://doi.org/10.1101/2022.10.14.512269
https://doi.org/10.1101/2022.10.14.512269
Publikováno v:
eneuro. 10:ENEURO.0426-22.2023
The accumulation of α-synuclein (α-syn)-enriched protein aggregates is thought to arise from dysfunction in degradation systems within the brain. Recently, missense mutations ofSYNJ1encoding the SAC1 and 5’-phosphatase domains have been found in