Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sanjana Mahadev Bhat"'
Autor:
Sanjana Mahadev Bhat, Gary C. Sieck
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 6, Pp 159-176 (2024)
Abstract Succinate dehydrogenase (SDH) is a key mitochondrial enzyme involved in the tricarboxylic acid cycle, where it facilitates the oxidation of succinate to fumarate, and is coupled to the reduction of ubiquinone in the electron transport chain
Externí odkaz:
https://doaj.org/article/8c3e988224004336823416fd64b1b4a3
Autor:
Sanjana Mahadev Bhat, Jane Q. Yap, Oscar A. Ramirez-Ramirez, Philippe Delmotte, Gary C. Sieck
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11506 (2023)
Cellular mitochondrial function can be assessed using high-resolution respirometry that measures the O2 consumption rate (OCR) across a number of cells. However, a direct measurement of cellular mitochondrial function provides valuable information an
Externí odkaz:
https://doaj.org/article/2a8447c0065e4d939f6aed211fe0bed4
Autor:
Denusha Shrestha, Nyzil Massey, Sanjana Mahadev Bhat, Tomislav Jelesijević, Orhan Sahin, Qijing Zhang, Kristina L. Bailey, Jill A. Poole, Chandrashekhar Charavaryamath
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Agriculture workers report various respiratory symptoms owing to occupational exposure to organic dust (OD) and various gases. Previously, we demonstrated that pre-exposure to hydrogen sulfide (H2S) alters the host response to OD and induces oxidativ
Externí odkaz:
https://doaj.org/article/7427504c1c97496bab84613360a7b72a
Autor:
Nyzil Massey, Denusha Shrestha, Sanjana Mahadev Bhat, Piyush Padhi, Chong Wang, Locke A. Karriker, Jodi D. Smith, Anumantha G. Kanthasamy, Chandrashekhar Charavaryamath
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Increased incidences of neuro-inflammatory diseases in the mid-western United States of America (USA) have been linked to exposure to agriculture contaminants. Organic dust (OD) is a major contaminant in the animal production industry and is central
Externí odkaz:
https://doaj.org/article/a2081a74fdf84bb4b933a22662c65ab0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5788 (2023)
Proinflammatory cytokines such as TNFα mediate airway inflammation. Previously, we showed that TNFα increases mitochondrial biogenesis in human ASM (hASM) cells, which is associated with increased PGC1α expression. We hypothesized that TNFα induc
Externí odkaz:
https://doaj.org/article/8614addf129547f9b633481918f9a101
Autor:
Sanjana Mahadev Bhat, Nyzil Massey, Locke A. Karriker, Baljit Singh, Chandrashekhar Charavaryamath
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Animal production workers are persistently exposed to organic dust and can suffer from a variety of respiratory disease symptoms and annual decline in lung function. The role of high mobility group box-1 (HMGB1) in inflammatory ai
Externí odkaz:
https://doaj.org/article/6fbc1ac81e164432972d2f7e02ff3d01
Publikováno v:
Physiology. 38
Succinate dehydrogenase (SDH) is a key enzyme in the tricarboxylic acid (TCA) cycle, as well as Complex II of the electron transport chain (ETC). In the SDH reaction, succinate is oxidized to fumarate in the TCA cycle, producing FADH2 contributing to
Autor:
Sanjana Mahadev Bhat, Gary Sieck
Publikováno v:
Physiology. 38
Succinate dehydrogenase (SDH) is a mitochondrial enzyme that participates in both the tricarboxylic acid (TCA) cycle and the electron transport chain (ETC) as Complex II. In the TCA cycle, SDH catalyzes the oxidation of succinate to fumarate, which i
Publikováno v:
Physiology. 38
Airway inflammation is the central driver behind the pathogenesis of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, and the very recent pandemic outbreak of COVID-19. Previous studies reported t
Publikováno v:
Physiology. 38
Mitophagy is a regulated multistep process of selective removal of dysfunctional/damaged mitochondria by autophagy and is critical for the regulation of mitochondrial quality control in many physiological processes. The best characterized pathway of