Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sanjana Gopalakrishnan"'
Autor:
Sanjana Gopalakrishnan, Aarohi Gupta, Dorcas Matuwana, John J. Amante, Cathal J. Kearney, Vincent M. Rotello
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101909- (2022)
Applications involving ultrasound treatment as a therapeutic strategy have gained interest due to its enhanced tissue penetration, broad availability, and minimal invasiveness. Recently, ultrasound treatment has been utilized for applications such as
Externí odkaz:
https://doaj.org/article/933b07a4378b43898fedcb32347733b3
Autor:
Stefano Fedeli, Rui Huang, Yavuz Oz, Xianzhi Zhang, Aarohi Gupta, Sanjana Gopalakrishnan, Jessa Marie V. Makabenta, Stephanie Lamkin, Amitav Sanyal, Yisheng Xu, Vincent M. Rotello
Publikováno v:
ACS Applied Materials & Interfaces. 15:15260-15268
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122ecda2b013b24f431a35261199cf13
https://doi.org/10.1021/acsami.3c02640
https://doi.org/10.1021/acsami.3c02640
Autor:
Li-Sheng Wang, Sanjana Gopalakrishnan, Aarohi Gupta, Ruptanu Banerjee, Yi-Wei Lee, Vincent M. Rotello
Publikováno v:
Langmuir. 38:11675-11682
High internal phase emulsions (HIPEs) provide a versatile platform for encapsulating large volumes of therapeutics that are immiscible in water. A stable scaffold is obtained by polymerizing the external phase, resulting in polyHIPEs. However, fabric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afe899f689378d62125317bee3f4153
https://doi.org/10.1021/acs.langmuir.2c01565
https://doi.org/10.1021/acs.langmuir.2c01565
Autor:
David C. Luther, Yi-Wei Lee, Harini Nagaraj, Vincent Clark, Taewon Jeon, Ritabrita Goswami, Sanjana Gopalakrishnan, Stefano Fedeli, William Jerome, James L. Elia, Vincent M. Rotello
Publikováno v:
ACS Nano. 16:7323-7330
Current strategies for the delivery of proteins into cells face general challenges of endosomal entrapment and concomitant degradation of protein cargo. Efficient delivery directly to the cytosol overcomes this obstacle: we report here the use of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09234c807e77d9a7b990de0b901cf83e
https://doi.org/10.1021/acsnano.1c06768
https://doi.org/10.1021/acsnano.1c06768
Direct Cytosolic Delivery of Proteins Using Lyophilized and Reconstituted Polymer-Protein Assemblies
Autor:
David C. Luther, Harini Nagaraj, Ritabrita Goswami, Yağız Anıl Çiçek, Taewon Jeon, Sanjana Gopalakrishnan, Vincent M. Rotello
Publikováno v:
Pharmaceutical Research. 39:1197-1204
Cytosolic delivery of proteins accesses intracellular targets for chemotherapy and immunomodulation. Current delivery systems utilize inefficient endosomal pathways of uptake and escape that lead to degradation of delivered cargo. Cationic poly(oxano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b569110fcc9db3159467739de6c2f0
https://doi.org/10.1007/s11095-022-03226-w
https://doi.org/10.1007/s11095-022-03226-w
Autor:
Sanjana Gopalakrishnan, Aarohi Gupta, Jessa M. V. Makabenta, Jungmi Park, John J. Amante, Aritra Nath Chattopadhyay, Dorcas Matuwana, Cathal J. Kearney, Vincent M. Rotello
Publikováno v:
Advanced healthcare materials. 11(21)
Bacterial biofilms are a major healthcare concern resulting in refractory conditions such as chronic wounds, implant infections and failure, and multidrug-resistant infections. Aggressive and invasive strategies are employed to cure biofilm infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ce47e496eb3ba8eb737955da4e8209
https://pubmed.ncbi.nlm.nih.gov/36049222
https://pubmed.ncbi.nlm.nih.gov/36049222
Autor:
Taewon Jeon, Vincent M. Rotello, Yi-Wei Lee, Cameron W. Evans, Marck Norret, William Jerome, Sanjana Gopalakrishnan, K. Swaminathan Iyer, Jessica A. Kretzmann, David C. Luther
Publikováno v:
Journal of the American Chemical Society. 143:4758-4765
Intracellular protein delivery enables selective regulation of cellular metabolism, signaling, and development through introduction of defined protein quantities into the cell. Most applications require that the delivered protein has access to the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28ab3c700759929cac38c461a3d7de3
https://doi.org/10.1021/jacs.1c00258
https://doi.org/10.1021/jacs.1c00258
Autor:
Vincent M. Rotello, Shuting Pan, Jonathan P. Lee, Sankaran Thayumanavan, Sanjana Gopalakrishnan, Ann Fernandez, Li-Sheng Wang, Xuexin Duan, Yang Bai
Publikováno v:
Langmuir. 37:2826-2832
Hydrodynamic approaches are important for biomedical diagnostics, chemical analysis, and a broad range of industrial applications. Size-based separation and sorting is an important tool for these applications. We report the integration of hypersound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a42f79be127b112544b62920f1489c
https://doi.org/10.1021/acs.langmuir.0c03598
https://doi.org/10.1021/acs.langmuir.0c03598
Autor:
Sanjana Gopalakrishnan, Xianzhi Zhang, Roberto-Cao Milán, Taewon Jeon, Aarohi Gupta, Yuanchang Liu, Akash Gupta, Vincent M. Rotello, Jessa Marie Makabenta, Riddha Das, Rui Huang
Publikováno v:
Mater Horiz
Bioorthogonal transformation of imaging and therapeutic substrates using transition metal catalysts (TMCs) provides a toolkit with diverse applications in biomedicine. Controlled localization of bioorthogonal catalysis is key for enhancing their ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5213fd4d39708a4db731ea38346468
https://doi.org/10.1039/d1mh01408k
https://doi.org/10.1039/d1mh01408k
Autor:
Rui Huang, Xianzhi Zhang, Sanjana Gopalakrishnan, Aarohi Gupta, Stefano Fedeli, David C. Luther, Vincent M. Rotello
Publikováno v:
ChemBioChem. 21:2759-2763
We demonstrate here the protection of biorthogonal transition metal catalysts (TMCs) in biological environments by using self-assembled monolayers on gold nanoparticles (AuNPs). Encapsulation of TMCs in this hydrophobic environment preserves catalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b77ae136ed821abcfdd5ed60ebf367ef
https://doi.org/10.1002/cbic.202000207
https://doi.org/10.1002/cbic.202000207