Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sanjai K. Pathak"'
Autor:
Dibyendu Dana, Tuhin Das, Athena Choi, Ashif I. Bhuiyan, Tirtha K. Das, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v:
Molecules, Vol 27, Iss 2, p 347 (2022)
Cell cycle kinases represent an important component of the cell machinery that controls signal transduction involved in cell proliferation, growth, and differentiation. Nek2 is a mitotic Ser/Thr kinase that localizes predominantly to centrosomes and
Externí odkaz:
https://doaj.org/article/b20092a5706147759b034d8e80a93c73
Autor:
Dibyendu Dana, Sanjai K. Pathak
Publikováno v:
Molecules, Vol 25, Iss 3, p 698 (2020)
Human cathepsin L belongs to the cathepsin family of proteolytic enzymes with primarily an endopeptidase activity. Although its primary functions were originally thought to be only of a housekeeping enzyme that degraded intracellular and endocytosed
Externí odkaz:
https://doaj.org/article/8208da32d78d46f588a600d81190ec10
GPR171 activation regulates morphine tolerance but not withdrawal in a test-dependent manner in mice
Publikováno v:
Behavioural pharmacology. 33(7)
A newly deorphanized G protein-coupled receptor, GPR171, is found to be highly expressed within the periaqueductal gray, a pain-modulating region in the brain. Our recent research has shown that a GPR171 agonist increases morphine antinociception in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da12bf564834d823afb9e9e7685ff00e
https://pubmed.ncbi.nlm.nih.gov/35942845
https://pubmed.ncbi.nlm.nih.gov/35942845
Autor:
Ashif I. Bhuiyan, Athena H. Choi, Sarbani Ghoshal, Ugochi A. Adiele, Dibyendu Dana, Jun Yong Choi, Karl R. Fath, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 88:129288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::260eeff506f95ba1df758c251f4e8703
https://doi.org/10.1016/j.bmcl.2023.129288
https://doi.org/10.1016/j.bmcl.2023.129288
Autor:
Rafael Musayev, Lamia Hauter, Ashif I. Bhuiyan, Asha R. Santha, Anna A. Dickson, Alan J. Finkelstein, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91d9abd8e9dd5afb820c2feb4f006fb
https://doi.org/10.1096/fasebj.2022.36.s1.l7836
https://doi.org/10.1096/fasebj.2022.36.s1.l7836
Autor:
Ashif I. Bhuiyan, Asha Reghuvaran Santha, Tuhin Das, Dianne Hernandez, Rafael Musayev, Sarbani Ghoshal, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e2410d6ae21c48f828ca3d628c5cc2b
https://doi.org/10.1096/fasebj.2022.36.s1.l7801
https://doi.org/10.1096/fasebj.2022.36.s1.l7801
Autor:
Karl R. Fath, Dibyendu Dana, Jeremy Garcia, Sanjai K. Pathak, Pratikkumar Rathod, Laura Joo, Daniel A. Novoa, Suneeta Paroly, Emmanuel J. Chang, Ashif I. Bhuiyan
Publikováno v:
Bioorganic Chemistry. 85:505-514
Human cathepsin L is a ubiquitously expressed endopeptidase and is known to play critical roles in a wide variety of cellular signaling events. Its overexpression has been implicated in numerous human diseases, including highly invasive forms of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196198e6bb2c1b2fc560786f649308d7
https://doi.org/10.1016/j.bioorg.2019.02.032
https://doi.org/10.1016/j.bioorg.2019.02.032
Autor:
Uday Kiran Velagapudi, Dana Ferraris, Sanjai K. Pathak, Tanaji T. Talele, Xuwei Shao, Bhargav A. Patel
Publikováno v:
Expert opinion on therapeutic patents. 31(7)
Discovery of small molecules that impede the activity of single-strand DNA repair enzyme, PARP1, has led to four marketed drugs for the treatment of advanced-stage cancers. Hence, there is a renewed enthusiasm in the PARP inhibitor discovery arena. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6723a08c3de14b329f5b3b42c37923
https://pubmed.ncbi.nlm.nih.gov/33554679
https://pubmed.ncbi.nlm.nih.gov/33554679
Autor:
Dibyendu Dana, Sanjai K. Pathak
Publikováno v:
Molecules
Molecules, Vol 25, Iss 3, p 698 (2020)
Molecules, Vol 25, Iss 3, p 698 (2020)
Human cathepsin L belongs to the cathepsin family of proteolytic enzymes with primarily an endopeptidase activity. Although its primary functions were originally thought to be only of a housekeeping enzyme that degraded intracellular and endocytosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a2519ad225deae49b07fcc3522989f
https://pubmed.ncbi.nlm.nih.gov/32041276
https://pubmed.ncbi.nlm.nih.gov/32041276
Autor:
Faiza Rafi, Karl R. Fath, Anna A. Dickson, Tuhin Das, Guoshen Li, Gopal Subramaniam, Sarbani Ghoshal, Sanjai K. Pathak, Pratikkumar Rathod, Dibyendu Dana, Suneeta Paroly, Ashif I. Bhuiyan, Emmanuel J. Chang
Publikováno v:
Bioorganic Chemistry. 117:105463
Human cathepsin B is a cysteine-dependent protease whose roles in both normal and diseased cellular states remain yet to be fully delineated. This is primarily due to overlapping substrate specificities and lack of unambiguously annotated physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef6f0f68d423d40501e60e4599276b
https://doi.org/10.1016/j.bioorg.2021.105463
https://doi.org/10.1016/j.bioorg.2021.105463