Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Sanja Aveic"'
Autor:
Mario Capasso, Chiara Brignole, Vito A. Lasorsa, Veronica Bensa, Sueva Cantalupo, Enrico Sebastiani, Alessandro Quattrone, Eleonora Ciampi, Marianna Avitabile, Angela R. Sementa, Katia Mazzocco, Barbara Cafferata, Gabriele Gaggero, Valerio G. Vellone, Michele Cilli, Enzo Calarco, Elena Giusto, Patrizia Perri, Sanja Aveic, Doriana Fruci, Annalisa Tondo, Roberto Luksch, Rossella Mura, Marco Rabusin, Francesco De Leonardis, Monica Cellini, Paola Coccia, Achille Iolascon, Maria V. Corrias, Massimo Conte, Alberto Garaventa, Loredana Amoroso, Mirco Ponzoni, Fabio Pastorino
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB has improved in the last years, more than 50% of high-risk patients stil
Externí odkaz:
https://doaj.org/article/dbb768f368d643d1a5a9f03a388be936
Autor:
Simona Cocchi, Valentina Greco, Viktoryia Sidarovich, Jacopo Vigna, Francesca Broso, Diana Corallo, Jacopo Zasso, Angela Re, Emanuele Filiberto Rosatti, Sara Longhi, Andrea Defant, Federico Ladu, Vanna Sanna, Valentina Adami, Vito G. D’Agostino, Mattia Sturlese, Mario Sechi, Sanja Aveic, Ines Mancini, Denise Sighel, Alessandro Quattrone
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4795 (2024)
Neuroblastoma (NB) is the most commonly diagnosed extracranial solid tumor in children, accounting for 15% of all childhood cancer deaths. Although the 5-year survival rate of patients with a high-risk disease has increased in recent decades, NB rema
Externí odkaz:
https://doaj.org/article/9072403a072441278a6297dfa0bf5a34
Autor:
Matteo Stocchero, Diana Corallo, Silvia Bresolin, Marcella Pantile, Paola Pirillo, Roberta Bortolozzi, Sara Menegazzo, Daniele Boso, Giampietro Viola, Eugenio Baraldi, Alessandra Biffi, Giuseppe Giordano, Sanja Aveic
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1602 (2024)
The RNA-binding protein LIN28B, identified as an independent risk factor in high-risk neuroblastoma patients, is implicated in adverse treatment outcomes linked to metastasis and chemoresistance. Despite its clinical significance, the impact of LIN28
Externí odkaz:
https://doaj.org/article/5d7bbe2de33a4cab96d0d3c843414119
Autor:
Ramin Nasehi, Ali T. Abdallah, Marcella Pantile, Carlo Zanon, Michael Vogt, Stephan Rütten, Horst Fischer, Sanja Aveic
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100596- (2023)
A key challenge for the discovery of novel molecular targets and therapeutics against pediatric bone metastatic disease is the lack of bona fide in vitro cell models. Here, we show that a beta-tricalcium phosphate (β-TCP) multicellular 3D in vitro b
Externí odkaz:
https://doaj.org/article/4b52909b6cd841f8bd8253a895db5668
Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib
Autor:
Diana Corallo, Fabio Pastorino, Marcella Pantile, Elena Mariotto, Federico Caicci, Giampietro Viola, Mirco Ponzoni, Gian Paolo Tonini, Sanja Aveic
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Despite reported advances, acquired resistance to tyrosine kinase inhibitors still represents a serious problem in successful cancer treatment. Among this class of drugs, ponatinib (PON) has been shown to have notable long-term ef
Externí odkaz:
https://doaj.org/article/3544c2c213fe41539b897649ac845d8c
Autor:
Romeo Romagnoli, Paola Oliva, Filippo Prencipe, Stefano Manfredini, Federica Budassi, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Lorenzo Manfreda, Elena Mariotto, Roberta Bortolozzi, Giampietro Viola
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 1031 (2022)
A further investigation aiming to generate new potential antitumor agents led us to synthesize a new series of twenty-two compounds characterized by the presence of the 7-(3′,4′,5′-trimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine pharmacophor
Externí odkaz:
https://doaj.org/article/cc07dc069850450cb83a094b4295b925
Autor:
Paola Oliva, Romeo Romagnoli, Barbara Cacciari, Stefano Manfredini, Chiara Padroni, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Noemi Milan, Elena Mariotto, Giampietro Viola, Roberta Bortolozzi
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1191 (2022)
Two different series of fifty-two compounds, based on 3′,4′,5′-trimethoxyaniline (7a–ad) and variably substituted anilines (8a–v) at the 7-position of the 2-substituted-[1,2,4]triazolo [1,5-a]pyrimidine nucleus, had moderate to potent antip
Externí odkaz:
https://doaj.org/article/d51587f8f4754b5eb51cf08ab0edb9d3
Autor:
Stefania D’Agostino, Lucia Tombolan, Mattia Saggioro, Chiara Frasson, Elena Rampazzo, Stefania Pellegrini, Francesca Favaretto, Carlo Biz, Pietro Ruggieri, Piergiorgio Gamba, Paolo Bonvini, Sanja Aveic, Roberto Giovannoni, Michela Pozzobon
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundThe interplay between neoplastic cells and surrounding extracellular matrix (ECM) is one of the determinant elements for cancer growth. The remodeling of the ECM by cancer-associated fibroblasts (CAFs) shapes tumor microenvironment by depos
Externí odkaz:
https://doaj.org/article/5d6d08b0d65e44ffa7eb531abe642ae0
Autor:
Diana Corallo, Stella Frabetti, Olivia Candini, Elisa Gregianin, Massimo Dominici, Horst Fischer, Sanja Aveic
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The potential of tumor three-dimensional (3D) in vitro models for the validation of existing or novel anti-cancer therapies has been largely recognized. During the last decade, diverse in vitro 3D cell systems have been proposed as a bridging link be
Externí odkaz:
https://doaj.org/article/231dd31671cb4eacb18cd26ff8639172
Autor:
Sanja Aveic, Marcella Pantile, Pierfrancesco Polo, Viktoryia Sidarovich, Marilena De Mariano, Alessandro Quattrone, Luca Longo, Gian Paolo Tonini
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in cell transformation. Deregulated activity of RTKs in tumors can determine disease progression and therapeutic responses in sever
Externí odkaz:
https://doaj.org/article/610a9b66817943ddba1a02fad50d8ee0