Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Saniya M. Javadekar"'
Publikováno v:
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
Accumulating evidence suggests that human genome can fold into non-B DNA structures, when appropriate sequence and favourable conditions are present. Among these, G-quadruplexes (G4-DNA) are associated with gene regulation, chromosome fragility and t
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(3)
Maintaining genome integrity is crucial for normal cellular functions. DNA double-strand breaks (DSBs), when unrepaired, can potentiate chromosomal translocations. t(14;18) translocation involving BCL2 gene on chromosome 18 and IgH loci at chromosome
Publikováno v:
The FEBS journal. 282(14)
Integrity in entirety is the preferred state of any organism. The temporal and spatial integrity of the genome ensures continued survival of a cell. DNA breakage is the first step towards creation of chromosomal translocations. In this review, we hig
Autor:
Somesh Sharma, Rupa Kumari, Mrinal Srivastava, Sathees C. Raghavan, Monica Pandey, Saniya M. Javadekar
Publikováno v:
Cell Death & Disease
Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of classical NHEJ and is implicated in chromosom