Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Sanith Cheriyamundath"'
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Akademický článek
Cell–cell adhesion: linking Wnt/β-catenin signaling with partial EMT and stemness traits in tumorigenesis [version 1; referees: 4 approved]
Autor: Sayon Basu, Sanith Cheriyamundath, Avri Ben-Ze’ev
Publikováno v: F1000Research, Vol 7 (2018)
Changes in cell adhesion and motility are considered key elements in determining the development of invasive and metastatic tumors. Co-opting the epithelial-to-mesenchymal transition (EMT) process, which is known to occur during embryonic development
Externí odkaz: https://doaj.org/article/469de0077d66459ea31b428fb6d9fcd6
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4
A Necessary Role for Increased Biglycan Expression during L1-Mediated Colon Cancer Progression
Autor: Arka Saha, Sanith Cheriyamundath, Anmol Kumar, Nancy Gavert, Thomas Brabletz, Avri Ben-Ze’ev
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 445, p 445 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 445
International Journal of Molecular Sciences
Aberrant activation of Wnt/β-catenin signaling and downstream β-catenin-TCF target genes is a hallmark of colorectal cancer (CRC) development. We identified the immunoglobulin-like cell adhesion receptor L1CAM (L1) as a target of β-catenin-TCF tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d23882a28b2471380a8fb36bbc69fbc
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/20658
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5
The Collagen-Modifying Enzyme PLOD2 Is Induced and Required during L1-Mediated Colon Cancer Progression
Autor: Sanith Cheriyamundath, Nancy Gavert, Avri Ben-Ze'ev, Anmol Kumar, Thomas Brabletz
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3552, p 3552 (2021)
The overactivation of Wnt/β-catenin signaling is a hallmark of colorectal cancer (CRC) development. We identified the cell adhesion molecule L1CAM (L1) as a target of β-catenin-TCF transactivation in CRC cells. The overexpression of L1 in CRC cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7c07e570f61160a36b3ad5aa9276e5
https://pubmed.ncbi.nlm.nih.gov/33805564
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6
Wnt/β-Catenin Target Genes in Colon Cancer Metastasis: The Special Case of L1CAM
Autor: Avri Ben-Ze'ev, Sanith Cheriyamundath
Publikováno v: Cancers
Cancers, Vol 12, Iss 3444, p 3444 (2020)
Simple Summary The Wnt/β-catenin cell–cell signaling pathway is one of the most basic and highly conserved pathways for intercellular communications regulating key steps during development, differentiation, and cancer. In colorectal cancer (CRC),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b57d93e0d3a3e693e55a17a1a6ddf41
https://pubmed.ncbi.nlm.nih.gov/33228199
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7
Aqueous extract of Triphala inhibits cancer cell proliferation through perturbation of microtubule assembly dynamics
Autor: Ramakrishna V. Hosur, Sanith Cheriyamundath, Manu Lopus, Tejashree Mahaddalkar, Shreyada N. Save, Sinjan Choudhary
Publikováno v: Biomedicine & Pharmacotherapy. 98:76-81
Triphala (Trl) is an ayurvedic formulation used for treating disorders of the digestive, respiratory, and nervous systems. Its anticancer properties have also been documented. We studied effects of Trl on tubulin, a target protein for several antican
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d544a256db6cdb45ec61d2ae2cb7799
https://doi.org/10.1016/j.biopha.2017.12.022
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8
Chemical characteristics, antioxidant and anticancer potential of sulfated polysaccharides from Chlamydomonas reinhardtii
Autor: V. L. Sirisha, Sanith Cheriyamundath, Priyanka Kamble, Manu Lopus
Publikováno v: Journal of Applied Phycology. 30:1641-1653
The sulfated polysaccharides (SPs) from Chlamydomonas reinhardtii (Cr) were isolated by hot water method using 80% alcohol and semi purified by anion-exchange column chromatography. The chemical analysis of the extract showed 78% carbohydrates, 18% r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59ea8e921a3ab0e89e02b222238bcd90
https://doi.org/10.1007/s10811-018-1397-2
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9
Tryptone-stabilized gold nanoparticles target tubulin and inhibit cell viability by inducing an unusual form of cell cycle arrest
Autor: Tejashree Mahaddalkar, Sanith Cheriyamundath, H. Muthurajan, Sourabh Mehta, Manu Lopus
Publikováno v: Experimental Cell Research. 360:163-170
Gold nanoparticles have been investigated extensively for their molecular mechanisms of action and anticancer potential. We report a novel, tubulin-targeted antiproliferative mechanism of action of tryptone-stabilized gold nanoparticles (TsAuNPs). Ts
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fe6161fd782379f89daaed143826aa
https://doi.org/10.1016/j.yexcr.2017.09.002
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10
Safranal Inhibits HeLa Cell Viability by Perturbing the Reassembly Potential of Microtubules
Autor: Sinjan Choudhary, Sanith Cheriyamundath, Manu Lopus
Publikováno v: Phytotherapy Research. 32:170-173
Saffron, a spice from Crocus sativus, has been known for its health benefits and medicinal properties. Safranal is a component of saffron and is known for its antioxidant and anticancer properties. In this study, we elucidated a possible tubulin-targ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b50d4af35ab63dd836eca2cb466ff0d
https://doi.org/10.1002/ptr.5938
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