Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sanil Kunjir"'
Autor:
Giuseppe Campiani, Sanil Kunjir, Stefania Butini, Ettore Novellino, Sandra Gemma, Margherita Brindisi
Publikováno v:
Tetrahedron Letters. 54:1233-1235
As a part of our work in the development of novel antimalarials, we were interested in elaborating an appropriate synthetic strategy for the preparation of endoperoxide-containing bridged bicyclic scaffolds. Through a TMSOTf-promoted dehydrative cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6166c023c0e001fe787e6bed162fcf14
https://doi.org/10.1016/j.tetlet.2012.12.075
https://doi.org/10.1016/j.tetlet.2012.12.075
Autor:
Annette Habluetzel, Luisa Di Cerbo, Stefania Lamponi, Sandra Gemma, Giuseppe Campiani, Silvia Parapini, Stefania Butini, Donatella Taramelli, Sarah D'Alessandro, Sofia Tapanelli, Sanil Kunjir, Margherita Brindisi, Ettore Novellino, Simone Brogi
Here we report the development of a straightforward synthetic procedure for the preparation of spirocyclic endoperoxides as synthetic analogues of the natural product dihydroplakortin. The peroxides presented here are more potent antiplasmodials than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e406f004b6096c573794f2c72b01b0a
http://hdl.handle.net/11588/825361
http://hdl.handle.net/11588/825361
Autor:
Annette Habluetzel, Ettore Novellino, Emanuele Gabellieri, Gagan Kukreja, Isabella Fiorini, Stefania Butini, Roberta Gualdani, Luisa Savini, Sandra Gemma, Simone Brogi, Caterina Camodeca, Stefania Lamponi, Donatella Taramelli, Sanil Kunjir, Margherita Brindisi, Massimo Valoti, Gianluca Bartolommei, Giuseppe Campiani, Rowena E. Martin, Leonardo Lucantoni, Maria Rosa Moncelli, Francesco Tadini-Buoninsegni, Robert L. Summers, Nicoletta Basilico
Publikováno v:
Journal of medicinal chemistry. 55(23)
The intramolecular hydrogen bond formed between a protonated amine and a neighboring H-bond acceptor group in the side chain of amodiaquine and isoquine is thought to play an important role in their antimalarial activities. Here we describe isoquine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bdab497576b87e5a56f7ffbf05bfd4
https://pubmed.ncbi.nlm.nih.gov/23145816
https://pubmed.ncbi.nlm.nih.gov/23145816
Autor:
Salvatore Sanna Coccone, Silvia Parapini, Simone Brogi, Nicoletta Basilico, Donatella Taramelli, Margherita Brindisi, Ettore Novellino, Vittoria Moretti, Giuseppe Campiani, Stefania Butini, Sandra Gemma, Sanil Kunjir
Here we report the synthesis and evaluation of antiplasmodial activity of a novel series of bicyclic peroxides inspired by the marine natural compound dihydroplakortin. We developed a synthetic strategy leading to the dihydroplakortin-related peroxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5580e3fc83429fa698488f8ed9e843fa
http://hdl.handle.net/11365/19027
http://hdl.handle.net/11365/19027
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues.
Autor:
Sandra Gemma, Sanil Kunjir, Salvatore Sanna Coccone, Margherita Brindisi, Vittoria Moretti, Simone Brogi, Ettore Novellino, Nicoletta Basilico, Silvia Parapini, Donatella Taramelli, Giuseppe Campiani, Stefania Butini
Publikováno v:
Journal of Medicinal Chemistry; Aug2011, Vol. 54 Issue 16, p5949-5953, 5p