Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sanika Bodas"'
Autor:
Sreyashi Bhattacharya, Hannah L. Harris, Ridwan Islam, Sanika Bodas, Navatha Polavaram, Juhi Mishra, Dipanwita Das, Parthasarathy Seshacharyulu, Achyuth Kalluchi, Anirban Pal, Manish Kohli, Subodh M. Lele, Michael Muders, Surinder K. Batra, Paramita M. Ghosh, Kaustubh Datta, M. Jordan Rowley, Samikshan Dutta
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-18 (2024)
Abstract Resistance to the current Androgen Receptor Signaling Inhibitor (ARSI) therapies has led to higher incidences of therapy-induced neuroendocrine-like prostate cancer (t-NEPC). This highly aggressive subtype with predominant small-cell-like ch
Externí odkaz:
https://doaj.org/article/2b98ea921a8d460aa22a9de1beae8f05
Autor:
Satoko Matsumura, Emi Shimizu, Amel Dudakovic, Andre J. van Wijnen, Marwa Choudhury, Daniel H. Fine, Siva P.V. Nadimpalli, Yoshifumi Kobayashi, Henry F. Duncan, Richard Johnson, Angela Quispe-Salcedo, Sanika Bodas, Erhao Li
Publikováno v:
Biochem Biophys Res Commun
Enhancer of zeste homolog 2 (EZH2) is the catalytic core of polycomb repressive complex 2 (PRC2), which primarily methylates lysine 27 on histone H3 (H2K27me3), generating transcriptionally suppressed heterochromatin. Since EZH2 suppresses expression
Autor:
Samikshan Dutta, Navatha Shree Polavaram, Ridwan Islam, Sreyashi Bhattacharya, Sanika Bodas, Thomas Mayr, Sohini Roy, Sophie Alvarez Y. Albala, Marieta I. Toma, Anza Darehshouri, Angelika Borkowetz, Stefanie Conrad, Susanne Fuessel, Manfred Wirth, Gustavo B. Baretton, Lorenz C. Hofbauer, Paramita Ghosh, Kenneth J. Pienta, David L. Klinkebiel, Surinder K. Batra, Michael H. Muders, Kaustubh Datta
Publikováno v:
Oncogene, vol 41, iss 30
Oncogene
Oncogene
Aberrant transcriptional activity of androgen receptor (AR) is one of the dominant mechanisms for developing of castration-resistant prostate cancer (CRPC). Analyzing AR-transcriptional complex related to CRPC is therefore important towards understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc411ae2f19fc26c5aaf119fee4bc61
https://escholarship.org/uc/item/0p35m4xg
https://escholarship.org/uc/item/0p35m4xg
Autor:
Ridwan Islam, Juhi Mishra, Sanika Bodas, Sreyashi Bhattacharya, Surinder K. Batra, Samikshan Dutta, Kaustubh Datta
Publikováno v:
Cancer metastasis reviews. 41(3)
Neuropilins (NRPs) are transmembrane proteins involved in vascular and nervous system development by regulating angiogenesis and axon guidance cues. Several published reports have established their role in tumorigenesis. NRPs are detectable in tumor
Autor:
Ridwan Islam, Juhi Mishra, Navatha Shree Polavaram, Sreyashi Bhattacharya, Zhengdong Hong, Sanika Bodas, Sunandini Sharma, Alyssa Bouska, Tyler Gilbreath, Ahmed M. Said, Lynette M. Smith, Benjamin A. Teply, Michael H. Muders, Surinder K. Batra, Kaustubh Datta, Samikshan Dutta
Publikováno v:
Cell reports. 40(3)
Neuroendocrine (NE)-like tumors secrete various signaling molecules to establish paracrine communication within the tumor milieu and to create a therapy-resistant environment. It is important to identify molecular mediators that regulate this secreto
Autor:
Sreyashi Bhattacharya, Ridwan Islam, Sanika Bodas, Juhi Mishra, Dipanwita Das, Kaustubh Datta, Samikshan Dutta
Publikováno v:
Cancer Research. 82:LB037-LB037
Background: Prolonged ablation of androgen receptor pathway in prostate cancer leads to the emergence of therapy resistant neuroendocrine-like (NE-like) aggressive lineage. This NE development is associated with chromatin reprogramming underlying epi
Autor:
Benjamin A. Teply, Michael H. Muders, Zhengdong Hong, Sanika Bodas, Sreyashi Bhattacharya, Ridwan Islam, Samikshan Dutta, Kaustubh Datta, Navatha Shree Polavaram
Publikováno v:
Cancer Research. 81:1422-1422
Background: Prostate cancer (PCa) patient management is becoming increasingly challenging owing to the emergence of advanced therapy-resistant PCa. Published reports from our laboratory demonstrated that neuropilin-2 (NRP2), a non-tyrosine kinase tra
Autor:
Sanika Bodas, Navatha Shree Polavaram, Ridwan Islam, Sreyashi Bhattacharya, Kaustubh Datta, Samikshan Dutta
Publikováno v:
Cancer Research. 81:1326-1326
Background:Failure of castration resistant prostate cancer patients to Androgen Receptor Signaling Inhibitor (ARSI) poses a major challenge in terms of therapeutic development. The heterogeneous nature of prostate cancer makes it difficult to stratif
Autor:
Kaustubh Datta, Michael H. Muders, Sanika Bodas, Samikshan Dutta, Ridwan Islam, Navatha shree Polavaram, Benjamin A. Teply, Sreyashi Bhattacharya
Publikováno v:
Cancer Research. 81:1409-1409
INTRODUCTION:Patients with advanced prostate cancer often report resistance to standard ARSI (Androgen Receptor Signaling Inhibitor) therapy. One reason for such therapy resistance is the development of splice variants of Androgen Receptor (AR). Addi