Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sanie Mnaimneh"'
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
Autor:
Hamed S. Najafabadi, Michael Garton, Matthew T. Weirauch, Sanie Mnaimneh, Ally Yang, Philip M. Kim, Timothy R. Hughes
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background The C2H2 zinc finger (C2H2-ZF) is the most numerous protein domain in many metazoans, but is not as frequent or diverse in other eukaryotes. The biochemical and evolutionary mechanisms that underlie the diversity of this DNA-bindi
Externí odkaz:
https://doaj.org/article/c8a9f244e20f4218a7bbfebe86e3bbdc
Autor:
Alessandra M. Sullivan, Andrej A. Arsovski, Janne Lempe, Kerry L. Bubb, Matthew T. Weirauch, Peter J. Sabo, Richard Sandstrom, Robert E. Thurman, Shane Neph, Alex P. Reynolds, Andrew B. Stergachis, Benjamin Vernot, Audra K. Johnson, Eric Haugen, Shawn T. Sullivan, Agnieszka Thompson, Fidencio V. Neri III, Molly Weaver, Morgan Diegel, Sanie Mnaimneh, Ally Yang, Timothy R. Hughes, Jennifer L. Nemhauser, Christine Queitsch, John A. Stamatoyannopoulos
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 2015-2030 (2014)
Our understanding of gene regulation in plants is constrained by our limited knowledge of plant cis-regulatory DNA and its dynamics. We mapped DNase I hypersensitive sites (DHSs) in A. thaliana seedlings and used genomic footprinting to delineate ∼
Externí odkaz:
https://doaj.org/article/eb2965a5058047bd8d6435cb1f0f6504
Autor:
Kamesh Narasimhan, Samuel A Lambert, Ally WH Yang, Jeremy Riddell, Sanie Mnaimneh, Hong Zheng, Mihai Albu, Hamed S Najafabadi, John S Reece-Hoyes, Juan I Fuxman Bass, Albertha JM Walhout, Matthew T Weirauch, Timothy R Hughes
Publikováno v:
eLife, Vol 4 (2015)
Caenorhabditis elegans is a powerful model for studying gene regulation, as it has a compact genome and a wealth of genomic tools. However, identification of regulatory elements has been limited, as DNA-binding motifs are known for only 71 of the est
Externí odkaz:
https://doaj.org/article/f5fb0c93967e4b798b4863e1ee5801aa
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003479 (2013)
Nucleosomes in all eukaryotes examined to date adopt a characteristic architecture within genes and play fundamental roles in regulating transcription, yet the identity and precise roles of many of the trans-acting factors responsible for the establi
Externí odkaz:
https://doaj.org/article/d46d84d9a4f64ae9889abeeeb6fa471b
Autor:
Frances L Jourd'heuil, Anthony M Lowery, Elaina M Melton, Sanie Mnaimneh, Nathan S Bryan, Bernadette O Fernandez, Joo-Ho Park, Chung-Eun Ha, Nadhipuram V Bhagavan, Martin Feelisch, David Jourd'heuil
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14400 (2010)
S-nitrosation--the formation of S-nitrosothiols (RSNOs) at cysteine residues in proteins--is a posttranslational modification involved in signal transduction and nitric oxide (NO) transport. Recent studies would also suggest the formation of N-nitros
Externí odkaz:
https://doaj.org/article/9e401a980b4a4d5dbb9b4080e9c368e1
Autor:
Ernest Radovani, Michael Garton, Brendan J. Frey, Mihai Albu, Kathy N. Lam, Matthew T. Weirauch, Ally Yang, Frank W. Schmitges, Hamed S. Najafabadi, Sanie Mnaimneh, Philip M. Kim, Jack Greenblatt, Timothy P. Hughes
Publikováno v:
Nature Biotechnology. 33:555-562
Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors. However, for most C2H2-ZF proteins it is unknown whether they even bind DNA or, if they do, to which sequences. Here, by combining data from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc163aab84b32fd0cb9872a459e4d1b8
https://doi.org/10.1038/nbt.3128
https://doi.org/10.1038/nbt.3128
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
Autor:
Michael Garton, Matthew T. Weirauch, Philip M. Kim, Hamed S. Najafabadi, Timothy P. Hughes, Ally Yang, Sanie Mnaimneh
Publikováno v:
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Background The C2H2 zinc finger (C2H2-ZF) is the most numerous protein domain in many metazoans, but is not as frequent or diverse in other eukaryotes. The biochemical and evolutionary mechanisms that underlie the diversity of this DNA-binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c487073fa962270439340ba85469dc39
http://europepmc.org/articles/PMC5588721
http://europepmc.org/articles/PMC5588721
Autor:
Shaheynoor Talukder, Savina Jaeger, Lourdes Peña-Castillo, Quaid Morris, Gwenael Badis, Sanie Mnaimneh, Olga B. Botvinnik, Esther T. Chan, Anthony A. Philippakis, Andrew R. Gehrke, Trevis M. Alleyne, Martha L. Bulyk, Wen Zhang, Daniel E. Newburger, Timothy P. Hughes, Michael F. Berger, Faiqua Khalid
Publikováno v:
Cell
Cell, Elsevier, 2008, 133 (7), pp.1266-1276. ⟨10.1016/j.cell.2008.05.024⟩
Cell, Elsevier, 2008, 133 (7), pp.1266-1276. ⟨10.1016/j.cell.2008.05.024⟩
International audience; Most homeodomains are unique within a genome, yet many are highly conserved across vast evolutionary distances, implying strong selection on their precise DNA-binding specificities. We determined the binding preferences of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d6a039be6465e1d104159af1e8648a
Autor:
Juan I. Fuxman Bass, Hamed S. Najafabadi, Kamesh Narasimhan, Hong Zheng, Matthew T. Weirauch, Sanie Mnaimneh, Samuel A. Lambert, Timothy P. Hughes, Jeremy Riddell, Ally Yang, Mihai Albu, John S. Reece-Hoyes, Albertha J.M. Walhout
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
Caenorhabditis elegans is a powerful model for studying gene regulation, as it has a compact genome and a wealth of genomic tools. However, identification of regulatory elements has been limited, as DNA-binding motifs are known for only 71 of the est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d747e34b758fd15985d0a0a108a6d54
https://doi.org/10.7554/elife.06967
https://doi.org/10.7554/elife.06967
Autor:
Sanie Mnaimneh, Mihai Albu, Juan I. Fuxman Bass, Samuel A. Lambert, Ally Yang, Jeremy Riddell, John S. Reece-Hoyes, Timothy P. Hughes, Albertha J.M. Walhout, Hamed S. Najafabadi, Matthew T. Weirauch, Kamesh Narasimhan, Hong Zheng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841cc5f6101e3363343405954ac3ffe9
https://doi.org/10.7554/elife.06967.038
https://doi.org/10.7554/elife.06967.038
