Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Sanhong Liu"'
Autor:
Yanyan Zhang, Yun Huang, Dianping Yu, Mengting Xu, Hongmei Hu, Qing Zhang, Minchen Cai, Xiangxin Geng, Hongwei Zhang, Jianhua Xia, Mengmeng Guo, Dong Lu, Hanchi Xu, Linyang Li, Xing Zhang, Qun Wang, Sanhong Liu, Weidong Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4312-4328 (2024)
Programmed cell death ligand-1 (PD-L1) is a T cell inhibitory immune checkpoint molecule that interacts with programmed cell death-1 (PD-1) to promote immune escape of tumor cells. Compared with antibody therapies, small molecule drugs show better pr
Externí odkaz:
https://doaj.org/article/a7130bd47bb441cfbc68faa19f780568
Autor:
Jianhua Xia, Mengting Xu, Hongmei Hu, Qing Zhang, Dianping Yu, Minchen Cai, Xiangxin Geng, Hongwei Zhang, Yanyan Zhang, Mengmeng Guo, Dong Lu, Hanchi Xu, Linyang Li, Xing Zhang, Qun Wang, Sanhong Liu, Weidong Zhang
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Targeting the programmed cell death 1/programmed cell death ligand 1 (PD‐1/PD‐L1) pathway has been identified as a successful approach for tumor immunotherapy. Here, we identified that the small molecule 5,7,4′‐trimethoxyflavone (TF)
Externí odkaz:
https://doaj.org/article/285e459a7517435b8986ba1757e739ae
Autor:
Haiyang Zhou, Yiwen Shen, Guangyong Zheng, Beibei Zhang, Anqi Wang, Jing Zhang, Hao Hu, Jiayi Lin, Sanhong Liu, Xin Luan, Weidong Zhang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Mucinous colorectal adenocarcinoma (MCA) is a distinct subtype of colorectal cancer (CRC) with the most aggressive pattern, but effective treatment of MCA remains a challenge due to its vague pathological characteristics. An in‐
Externí odkaz:
https://doaj.org/article/5c2a35749e57425598d7e28d4e314ec1
Publikováno v:
BMC Women's Health, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Endometriosis is a crippling, ongoing, chronic inflammatory condition. The management of these patients has been impacted by the current COVID-19 pandemic, which is still controversial. This study compared the clinical therapy out
Externí odkaz:
https://doaj.org/article/c1ae19a3ba5a4b7bb41f36c975e68cbf
Autor:
Wendan Zhang, Honghong Jiang, Gaosong Wu, Pengli Huang, Haonan Wang, Huazhang An, Sanhong Liu, Weidong Zhang
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host systemic inflammatory and immune response to infection.” At present, sepsis continues to pose a grave healthcare concern worldwide. Despite the use
Externí odkaz:
https://doaj.org/article/a3f8069b00b44c81926d445a17ebb1c9
Autor:
Wendan Zhang, Honghong Jiang, Pengli Huang, Gaosong Wu, Qun Wang, Xin Luan, Hongwei Zhang, Dianping Yu, Hongru Wang, Dong Lu, Haonan Wang, Huazhang An, Sanhong Liu, Weidong Zhang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Despite all modern advances in medicine, an effective drug for treating sepsis has yet to be found. The discovery of CMPK2 spurred hopes for the treatment of sepsis. However, CMPK2‐untapped target inhibitors are still an enormou
Externí odkaz:
https://doaj.org/article/e91a660634f44dc18f7ff796aed7242b
Autor:
Deji Ye, Hanshao Liu, Guojun Zhao, Aijun Chen, Yuhang Jiang, Yiming Hu, Dandan Liu, Ningxia Xie, Weifei Liang, Xi Chen, Haohao Zhang, Cuifeng Li, Jingyao Wang, Donglin Sun, Weifeng Chen, Dan Tan, Qi Wang, Hongru Wang, Dianping Yu, Baojin Wu, Mingliang Wang, Shuzhong Cui, Sanhong Liu, Xiaoren Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-13 (2023)
Abstract Chronic inflammation promotes the tumorigenesis and cell stemness maintenance of colorectal cancer (CRC). However, the bridge role of long noncoding RNA (lncRNA) in linking chronic inflammation to CRC development and progression needs better
Externí odkaz:
https://doaj.org/article/8f5e167018824e9b908ff9f0a0c7ef72
Autor:
Mei Xie, Jie Gao, Xidong Ma, Chongchong Wu, Xuelei Zang, Yuanyong Wang, Hui Deng, Jie Yao, Tingting Sun, Zhaofeng Yu, Sanhong Liu, Guanglei Zhuang, Xinying Xue, Jianlin Wu, Jianxin Wang
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Part-solid nodules (PSNs) have gradually shifted to defining special clinical subtypes. Commonly, the solid portions of PSNs show various radiological morphologies, of which the corresponding pathological basis and prognosis are u
Externí odkaz:
https://doaj.org/article/9e8b27b8e3024350844e35c63f27b105
Autor:
Fangping Ren, Mei Xie, Jie Gao, Chongchong Wu, Yang Xu, Xuelei Zang, Xidong Ma, Hui Deng, Jialin Song, Aiben Huang, Li Pang, Jin Qian, Zhaofeng Yu, Guanglei Zhuang, Sanhong Liu, Lei Pan, Xinying Xue
Publikováno v:
Cancer Medicine, Vol 11, Iss 15, Pp 2969-2977 (2022)
Abstract Objective Tertiary lymphoid structures (TLSs) are found in a variety of malignancies and affect the growth of tumors, but few studies have addressed their role in lung adenocarcinoma (LAC). We aimed to evaluate clinical features associated w
Externí odkaz:
https://doaj.org/article/5e7180979d064ff6b415e5746b2c3f95
Autor:
Yun Zhang, Shuaijun Li, Peisheng Jin, Ting Shang, Ruizhu Sun, Laiya Lu, Kaijin Guo, Jiping Liu, Yongjuan Tong, Junbang Wang, Sanhong Liu, Chen Wang, Yubin Kang, Wenmin Zhu, Qian Wang, Xiaoren Zhang, Feng Yin, Yi Eve Sun, Lei Cui
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Osteoarthritic (OA) is characterized by progressive destruction of joint cartilage. Here, the authors show that microRNA-17 plays a dual role in maintaining cartilage homeostasis and in the prevention of osteoarthritis, by targeting hypoxia-inducible
Externí odkaz:
https://doaj.org/article/3b7db89dabe548d4bf6e1fa709db1a48