Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sangwon F. Kim"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1390 (2024)
Non-alcoholic steatohepatitis (NASH) is an inflammatory form of non-alcoholic fatty liver disease (NAFLD), closely associated with disease progression, cirrhosis, liver failure, and hepatocellular carcinoma. Time-restricted feeding (TRF) has been sho
Externí odkaz:
https://doaj.org/article/29347079c5914612951e8474885b6fbd
Autor:
Richa Tyagi, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ik-Rak Jung, Sangwon F. Kim, Solomon H. Snyder, Bindu D. Paul
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107199- (2023)
Summary: Maintenance of redox balance plays central roles in a plethora of signaling processes. Although physiological levels of reactive oxygen and nitrogen species are crucial for functioning of certain signaling pathways, excessive production of f
Externí odkaz:
https://doaj.org/article/872d7538b9ac4ec9875a5b192c097dbe
Autor:
Jeanne M. Clark, W. Timothy Garvey, Kevin D. Niswender, Ann Marie Schmidt, Rexford S. Ahima, Jose O. Aleman, Ashley N. Battarbee, Joshua Beckman, Wendy L. Bennett, Nancy J. Brown, Paula Chandler‐Laney, Nancy Cox, Ira J. Goldberg, Kirk M. Habegger, Lorie M. Harper, Alyssa H. Hasty, Bertha A. Hidalgo, Sangwon F. Kim, Julie L. Locher, James M. Luther, Nisa M. Maruthur, Edgar R. Miller, Mary Ann Sevick, Quinn Wells
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 4 (2023)
ABSTRACT: As the worldwide prevalence of overweight and obesity continues to rise, so too does the urgency to fully understand mediating mechanisms, to discover new targets for safe and effective therapeutic intervention, and to identify biomarkers t
Externí odkaz:
https://doaj.org/article/dfc5fe5313eb46eda04ed5b4b43b5df4
Autor:
Becky Tu-Sekine, Sangwon F. Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6747 (2022)
All cells rely on nutrients to supply energy and carbon building blocks to support cellular processes. Over time, eukaryotes have developed increasingly complex systems to integrate information about available nutrients with the internal state of ene
Externí odkaz:
https://doaj.org/article/54bb9cfcb71445b3966dc6277321e372
Autor:
Reas S. Khan, Bailey Baumann, Kimberly Dine, Ying Song, Joshua L. Dunaief, Sangwon F. Kim, Kenneth S. Shindler
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Dysregulation of iron metabolism, and resultant cytotoxicity, has been implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative processes. Iron accumulation promotes cytotoxicity through various mechanisms includ
Externí odkaz:
https://doaj.org/article/d0bc350eede54e77b57423da0e937210
Autor:
Steven E. Arnold, Irwin Lucki, Bethany R. Brookshire, Gregory C. Carlson, Caroline A. Browne, Hala Kazi, Sookhee Bang, Bo-Ran Choi, Yong Chen, Mary F. McMullen, Sangwon F. Kim
Publikováno v:
Neurobiology of Disease, Vol 67, Iss , Pp 79-87 (2014)
Insulin resistance and other features of the metabolic syndrome are increasingly recognized for their effects on cognitive health. To ascertain mechanisms by which this occurs, we fed mice a very high fat diet (60% kcal by fat) for 17 days or a moder
Externí odkaz:
https://doaj.org/article/0f2c69c70c3044f080016390788f6f49
Publikováno v:
Journal of Cellular Physiology. 237:3421-3432
Hepatic glucose production (HGP) is crucial for the maintenance of normal glucose homeostasis. Although hepatic insulin resistance contributes to excessive glucose production, its mechanism is not well understood. Here, we show that inositol polyphos
Insulin resistance is a critical mediator of the development of non-alcoholic fatty liver disease (NAFLD). An excess influx of fatty acids to the liver is thought to be a pathogenic cause of insulin resistance and the development of non-alcoholic fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8635eaa7a0c8423d6433b7459d7c648
https://doi.org/10.1101/2023.04.26.538310
https://doi.org/10.1101/2023.04.26.538310
Hepatic glucose production is crucial for the maintenance of normal glucose homeostasis. Although hepatic insulin resistance contributes to excessive glucose production, its mechanism is not well understood. Here, we show that inositol polyphosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfeb19cec14c6bbb99a3e21be39e8025
https://doi.org/10.1101/2022.03.10.483655
https://doi.org/10.1101/2022.03.10.483655
Autor:
IkRak Jung, Becky Tu-Sekine, Sunghee Jin, Frederick Anokye-Danso, Rexford S Ahima, Todd T Brown, Sangwon F Kim
Publikováno v:
J Infect Dis
Background Antiretroviral therapy (ART) containing integrase strand transfer inhibitors (INSTIs) has been associated with weight gain in both ART initiation and switch studies, especially in women, but the underlying mechanisms are unclear. Methods T