Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sangsu Bang"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Excessive inflammation has been implicated in autism spectrum disorder (ASD), but the underlying mechanisms have not been fully studied. SHANK3 is a synaptic scaffolding protein and mutations of SHANK3 are involved in ASD. Shank3 expression in dorsal
Externí odkaz:
https://doaj.org/article/5609d08e859f4a66879311570b8b5490
Autor:
Kaiyuan Wang, Christopher R. Donnelly, Changyu Jiang, Yihan Liao, Xin Luo, Xueshu Tao, Sangsu Bang, Aidan McGinnis, Michael Lee, Matthew J. Hilton, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
There is an unmet clinical need to develop therapies to alleviate metastatic bone pain, frequently observed in patients with advanced cancers. Here, using mouse models of bone cancer pain, the authors show that STING agonists not only suppress bone c
Externí odkaz:
https://doaj.org/article/d82ef968c2e84210ad88047195778682
Autor:
Sangsu Bang, Christopher R. Donnelly, Xin Luo, Maria Toro-Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V. Bortsov, Emily R. Derbyshire, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.
Externí odkaz:
https://doaj.org/article/eb825ea936f54c5198d6ef87a574a599
Autor:
Jasmine Ji, Qianru He, Xin Luo, Sangsu Bang, Yutaka Matsuoka, Aidan McGinnis, Andrea G. Nackley, Ru-Rong Ji
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The incidence of chronic pain is especially high in women, but the underlying mechanisms remain poorly understood. Interleukin-23 (IL-23) is a pro-inflammatory cytokine and contributes to inflammatory diseases (e.g., arthritis and psoriasis) through
Externí odkaz:
https://doaj.org/article/b3173ca027da44d6b9058c5af98d108c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14426 (2022)
Inflammation is known to cause pain, and pain is of one of the cardinal signs of inflammation. Mounting evidence suggests that acute inflammation also resolves pain through specialized pro-resolving mediators (SPMs) and macrophage signaling. GPR37 is
Externí odkaz:
https://doaj.org/article/fc3ccbb1b06b4690871901e07494aaaf
Autor:
Gang Chen, Rou-Gang Xie, Yong-Jing Gao, Zhen-Zhong Xu, Lin-Xia Zhao, Sangsu Bang, Temugin Berta, Chul-Kyu Park, Mark Lay, Wei Chen, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The cellular mechanisms underlying acute pain transitions to chronic pain are poorly understood. Here the authors show that the scaffolding protein β-arrestin 2 contributes to these processes via desensitization of NMDA receptors in spinal neurons.
Externí odkaz:
https://doaj.org/article/d71d3fc96fe3477b80fc968a12f53cb5
Autor:
Linlin Zhang, Niccolò Terrando, Zhen-Zhong Xu, Sangsu Bang, Sven-Eric Jordt, William Maixner, Charles N. Serhan, Ru-Rong Ji
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Mechanisms of pain resolution are largely unclear. Increasing evidence suggests that specialized pro-resolving mediators (SPMs), derived from fish oil docosahexaenoic acid (DHA), promote the resolution of acute inflammation and potently inhibit infla
Externí odkaz:
https://doaj.org/article/c94811cb6ce14b11850909e8ebc33678
Autor:
Sangsu Bang1, Changyu Jiang1, Jing Xu1, Chandra, Sharat1, McGinnis, Aidan1, Xin Luo1, Qianru He1, Yize Li1, Zilong Wang1, Xiang Ao2, Parisien, Marc2, Fernandes de Araujo, Lorenna Oliveira2, Esfahani, Sahel Jahangiri2, Qin Zhang3, Tonello, Raquel4, Berta, Temugin4, Diatchenko, Luda2, Ru-Rong Ji1,5,6 ru-rong.ji@duke.edu
Publikováno v:
Journal of Clinical Investigation. 5/1/2024, Issue 9, p1-15. 15p.
Autor:
Thomas Buchheit, Yul Huh, Andrew Breglio, Sangsu Bang, Jing Xu, Yutaka Matsuoka, Ran Guo, Andrey Bortsov, Julio Reinecke, Peter Wehling, Tony Jun Huang, Ru-Rong Ji
Publikováno v:
Brain, Behavior, and Immunity. 111:298-311
Autor:
Aidan McGinnis, Yul Huh, Michael S. Lee, Sangsu Bang, Emma Huang, Natalia Bojorquez, Elmira Hezarkhani, Thomas Van De Ven, Christopher Donnelly, Ru-Rong Ji
Publikováno v:
The Journal of Pain. 24:20