Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sangseob Leem"'
Autor:
Beomsu Kim, Dan Say Kim, Joong-Gon Shin, Sangseob Leem, Minyoung Cho, Hanji Kim, Ki-Nam Gu, Jung Yeon Seo, Seung Won You, Alicia R. Martin, Sun Gyoo Park, Yunkwan Kim, Choongwon Jeong, Nae Gyu Kang, Hong-Hee Won
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Evidence for adaptation of human skin color to regional ultraviolet radiation suggests shared and distinct genetic variants across populations. However, skin color evolution and genetics in East Asians are understudied. We quantified skin co
Externí odkaz:
https://doaj.org/article/2a9f157042b54fc683b1ee301fb4ea34
Autor:
Jung Yeon Seo, Seung Won You, Ki-Nam Gu, Hanji Kim, Joong-Gon Shin, Sangseob Leem, Bo Kyoung Hwang, Yunkwan Kim, Nae Gyu Kang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Skin is a diverse ecosystem that provides a habitat for microorganisms. The skin condition and the skin microbiome interact each other under diverse environmental conditions. This study was conducted on 10 study participants for a one-year, from Sept
Externí odkaz:
https://doaj.org/article/c7cb37aa61984ff4a11e1344b911689a
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Big multi-omics data in bioinformatics often consists of a huge number of features and relatively small numbers of samples. In addition, features from multi-omics data have their own specific characteristics depending on whether they are from genomic
Externí odkaz:
https://doaj.org/article/a8754a62e3fd4ab39b22c938f178d5a3
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S2, Pp 11-20 (2018)
Abstract Background Gene-gene interactions (GGIs) are a known cause of missing heritability. Multifactor dimensionality reduction (MDR) is one of most commonly used methods for GGI detection. The generalized multifactor dimensionality reduction (GMDR
Externí odkaz:
https://doaj.org/article/e71e04fdc59e470a829a42822978b786
Autor:
Sangseob Leem, Taesung Park
Publikováno v:
Genomics & Informatics, Vol 16, Iss 4 (2018)
Gene-gene interaction is a key factor for explaining missing heritability. Many methods have been proposed to identify gene-gene interactions. Multifactor dimensionality reduction (MDR) is a well-known method for the detection of gene-gene interactio
Externí odkaz:
https://doaj.org/article/eeaefacdf0e6477f9377d78c34242999
Autor:
Kyung Kim, Moon-Woo Seong, Won-Hyong Chung, Sung Sup Park, Sangseob Leem, Won Park, Jihyun Kim, KiYoung Lee, Rae Woong Park, Namshin Kim
Publikováno v:
Genomics & Informatics, Vol 13, Iss 2, Pp 31-39 (2015)
Sequencing depth, which is directly related to the cost and time required for the generation, processing, and maintenance of next-generation sequencing data, is an important factor in the practical utilization of such data in clinical fields. Unfortu
Externí odkaz:
https://doaj.org/article/552e9c6ed5f14e26b43822f6a983f2e1
Autor:
Seo-Gyeong Lee, Joong-Gon Shin, Yunkwan Kim, Sangseob Leem, Sun Gyoo Park, Hong-Hee Won, Nae Gyu Kang
Publikováno v:
Journal of Investigative Dermatology. 142:2824-2827
Publikováno v:
Journal of Cosmetic Dermatology. 21:5203-5207
Skin assessment methodologies have focused mainly on intuitive aging characteristics, including facial wrinkles and pigmented spots, and usually adopt pattern recognition algorithms. Recently, distinct methods of interpreting skin aging, such as the
Autor:
Hong-Hee Won, Sangseob Leem, Yunkwan Kim, Joong-Gon Shin, Hae Jung Song, Sun Gyoo Park, Beomsu Kim, Seo-Gyeong Lee, Nae-Gyu Kang, Jung Yeon Seo
Publikováno v:
Journal of Investigative Dermatology. 141:555-562
Variation in skin pigmentation can be affected by both environmental factors and intrinsic factors such as age, gender, and genetic variation. Recent GWASs revealed that genetic variants of genes functionally related to a pigmentation pathway were as
Autor:
Nae-Gyu Kang, Sangseob Leem, Seo-Gyeong Lee, Hae Jung Song, Joong-Gon Shin, Kyunghoe Kim, Sun Gyoo Park, Yunkwan Kim, Seong Jin Kim, Jung Yeon Seo, Seung Won You
Publikováno v:
Skin Research and Technology. 27:86-92
Background The Janus-III measurement system evaluates the overall skin characteristics such as skin pore, wrinkle, sebum, porphyrin, skin pigmentation, and skin color using high-resolution facial images. The values are measured from five different fa