Systematic identification of biomarker-driven drug combinations to overcome resistance.

Autor: Rees MG; Broad Institute of MIT and Harvard, Cambridge, MA, USA. reesm@broadinstitute.org., Brenan L; Broad Institute of MIT and Harvard, Cambridge, MA, USA., do Carmo M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Duggan P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Mayo Clinic Alix School of Medicine, Rochester, MN, USA., Bajrami B; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arciprete M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Boghossian A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Vaimberg E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Johns Hopkins Hospital, Department of Pediatrics, Baltimore, MD, USA., Ferrara SJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lewis TA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rosenberg D; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sangpo T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Roth JA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kaushik VK; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Piccioni F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Merck Research Laboratories, Cambridge, MA, USA., Doench JG; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Johannessen CM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. johannes@broadinstitute.org.; Novartis Institutes for BioMedical Research, Cambridge, MA, USA. johannes@broadinstitute.org.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2022 Jun; Vol. 18 (6), pp. 615-624. Date of Electronic Publication: 2022 Mar 24.

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