Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sangmin You"'
Autor:
Sangmin You, Ai-Min Cui, Syed F. Hashmi, Xinmu Zhang, Christina Nadolny, Yuan Chen, Qiwen Chen, Xin Bush, Zachary Hurd, Winifer Ali, Gang Qin, Ruitang Deng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Preterm birth (PTB) is the leading cause of perinatal mortality and newborn complications with limited treatment options. Here the authors show that dysregulation of bile acids increases risk for PTB in pregnant women while restoring bile acid homeos
Externí odkaz:
https://doaj.org/article/722b7169c06244cc8e509e24c665a7d2
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170960 (2017)
Δ4-3-oxosteroid 5β-reductase is member D1 of the aldo-keto reductase family 1 (AKR1D1), which catalyzes 5β-reduction of molecules with a 3-oxo-4-ene structure. Bile acid intermediates and most of the steroid hormones carry the 3-oxo-4-ene structur
Externí odkaz:
https://doaj.org/article/a18a83b90f8446dea9fae35172921522
Publikováno v:
Molecules and cells. 45(5)
Process of manufacturing therapeutics exosome development for commercialization. The development of exosome treatment starts at the bench, and in order to be commercialized, it goes through the manufacturing, characterization, and formulation stages,
Autor:
Ai-Min Cui, Christina Nadolny, Yuan Chen, Qiwen Chen, Ruitang Deng, Sangmin You, Winifer Ali, Syed F. Hashmi, Zachary Hurd, Xin Bush, Gang Qin, Xinmu Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Preterm birth (PTB) is the leading cause of perinatal mortality and newborn complications. Bile acids are recognized as signaling molecules regulating a myriad of cellular and metabolic activities but have not been etiologically linked to PTB. In thi
Autor:
Yuan Chen, Christina Nadolny, Sangmin You, Mwlod Ghareeb, Liangran Guo, Ruitang Deng, Stephanie Shiffka, Ruchi Verma, Leila Valanejad, Fatemeh Akhlaghi
Publikováno v:
Molecular and Cellular Endocrinology. 470:127-141
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ4-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulating
Autor:
William B. Euler, Syrena C. Fernandes, Sangmin You, Christopher A. Latendresse, Kathleen M. Sullivan
Publikováno v:
Sensors and Actuators B: Chemical. 216:165-175
The reactions of dinitrotoluenes (DNT) with hydroxide ion or wet alkylamines can be used to detect and identify each isomer. The reaction products give visible spectra that can be used directly to determine the isomer speciation with sensitivities in
Autor:
Xiulong Song, Yuan Chen, Ruchi Verma, Alex Vasilenko, Stephanie Shiffka, Bingfang Yan, Ruitang Deng, Leila Valanejad, Leeza Hargreaves, Christina Nadolny, Sangmin You
Publikováno v:
Molecular Endocrinology. 29:613-626
Among diseases unique to pregnancy, intrahepatic cholestasis of pregnancy is the most prevalent disorder with elevated serum bile acid levels. We have previously shown that estrogen 17β-estradiol (E2) transrepresses bile salt export pump (BSEP) thro
Autor:
Leila, Valanejad, Mwlod, Ghareeb, Stephanie, Shiffka, Christina, Nadolny, Yuan, Chen, Liangran, Guo, Ruchi, Verma, Sangmin, You, Fatemeh, Akhlaghi, Ruitang, Deng
Publikováno v:
Molecular and cellular endocrinology. 470
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ(4)-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulatin
Publikováno v:
The Journal of Physical Chemistry A. 117:11167-11182
The reaction of trinitrotoluene (TNT) with bases has been investigated by NMR and visible spectroscopy methods. Hydroxide ion was found to react in one of two ways, either by deprotonation of the methyl group or by nucleophilic attack on the aromatic