Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sangmin Chang"'
1
Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer
Autor: Ashkon Rahbari, Wungki Park, Victoria M. Villaflor, Lauren Chiec, Bhoomika Sukhadia, Nisha Mohindra, Victor Wang, Garrett M. Frampton, Sangmin Chang, Jeffrey S. Ross, Si Wang, Zachary R. Chalmers, Siraj M. Ali, Jonathan F. Anker, Vaia Florou, Sang Ha Shin, Jeffrey H. Chuang, Pedro Viveiros, Lee Chun Park, Diana Saravia, Gilberto Lopes, Muhammad Mubbashir Sheikh, Young Kwang Chae, Ethan Sokol, Michael Oh
Publikováno v: Journal of Thoracic Oncology. 14:1807-1817
Introduction Presently, programmed death ligand 1 is the most commonly used biomarker to predict response to immune checkpoint inhibitors (ICIs) in NSCLC. Owing to its several limitations, there is continuous search for more precise and reliable mark
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b8b8003f7bbed1dee8bc4dd00df5a5
https://doi.org/10.1016/j.jtho.2019.06.016
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2
Mass spectrometry-based serum proteomic signature as a potential biomarker for survival in patients with non-small cell lung cancer receiving immunotherapy
Autor: Taeyeong Ko, Pedro Viveiros, Manali Bhave, Jonathan F. Anker, Anderson Cho, Young Kwang Chae, Won Bin Kim, Michael Oh, Nicholas I. Simon, Junho Song, Kyunghoon Rhee, Lee Chun Park, Andrew M. Davis, Sangmin Chang
Publikováno v: Transl Lung Cancer Res
Background VeriStrat test is a serum assay which uses a mass spectrometry (MS)-based proteomic signature derived from machine learning. It is currently used as a prognostic marker for patients with non-small cell lung cancer (NSCLC) receiving chemoth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612c60987b71ddd73eec2535220f16a0
https://pubmed.ncbi.nlm.nih.gov/32953481
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3
Epithelial-mesenchymal transition (EMT) signature is inversely associated with T-cell infiltration in non-small cell lung cancer (NSCLC)
Autor: Taeyeong Ko, Marcelo Rocha Cruz, Jonathan F. Anker, Kyoungmin Lee, Wooyoung M. Choi, Sangmin Chang, Wade T. Iams, Young Kwang Chae, Sarita Agte
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Epithelial-mesenchymal transition (EMT) is able to drive metastasis during progression of multiple cancer types, including non-small cell lung cancer (NSCLC). As resistance to immunotherapy has been associated with EMT and immune exclusion in melanom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9548940549793da2fd08203bbae24e5
https://doi.org/10.1038/s41598-018-21061-1
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8
Abstract 3693: Immunologic and clinical implications of polymerase δ (POLD) and Polymerase ϵ (POLE) gene mutations in non-small cell lung cancer (NSCLC)
Autor: Kyunghoon Rhee, Marcello Cruz, Anderson Cho, Sangmin Chang, Manali Bhave, Young Kwang Chae, Taeyeong Ko, Lee Chun Park, W. Iams, Andrew M. Davis
Publikováno v: Cancer Research. 78:3693-3693
POLD1 plays a role in proofreading the polymerase δ complex while POLE encodes the major catalytic and proofreading subunit of the polymerase ϵ complex. Mutations in POLD1 and POLE increase spontaneous somatic mutation rates which have been linked
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f69aec905168003fb1b42f82b6c1e05f
https://doi.org/10.1158/1538-7445.am2018-3693
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9
Abstract 4608: Immunologic and clinical implications of harboring mutations in mismatch repair (MMR) genes in non-small cell lung cancer (NSCLC)
Autor: Sangmin Chang, Lee Chun Park, Manali Bhave, Andrew M. Davis, Taeyeong Ko, Young Kwang Chae, W. Iams, Marcello Cruz, Anderson Cho, Kyunghoon Rhee
Publikováno v: Cancer Research. 78:4608-4608
MMR system is one of many cellular DNA repair mechanisms, verifying and maintaining repeat count of microsatellites during cell division. Mutations in MMR genes lead to increased genomic instability and tumor mutational burden (TMB). MMR gene mutatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::093d0d62e20084d86234304d971cbf88
https://doi.org/10.1158/1538-7445.am2018-4608
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