Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sangita Seshadri"'
Publikováno v:
Current Protein & Peptide Science. 10:456-463
Protein aggregation, being one of the hottest topics of modern protein science, is recognized now as a serious biomedical and biotechnological problem. Protein aggregation is considered as a causative factor (or at least an associated symptom) of a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6b901cff1294af891a15d5401a032d
https://doi.org/10.2174/138920309789351976
https://doi.org/10.2174/138920309789351976
Autor:
Vladimir N. Uversky, Sangita Seshadri, Bhavana Shivu, Keith A. Oberg, Anthony L. Fink, Jie Li
Publikováno v:
Biochemistry. 52(31)
Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) was used to study the conformation of aggregated proteins in vivo and in vitro. Several different protein aggregates, including amyloid fibrils from several peptides and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25a1f68ca8468e078be52ee20208da4
https://pubmed.ncbi.nlm.nih.gov/23837615
https://pubmed.ncbi.nlm.nih.gov/23837615
Autor:
David B. Bennett, Stevenson Cynthia L, Sangita Seshadri, Negar Sadrzadeh, John Howard, Joann M. Parker, Steven Gray, Richard Malcolmson, Harper Nancy Jane, Gregory W Sluggett, Jacqueline D. Schumacher, Phil Roberts, Steven White, Donald B Guzek, Patrick W Conley, Scot Cheu
Publikováno v:
Diabetes technologytherapeutics. 7(6)
Development of a product for pulmonary delivery of insulin presented significant technology challenges for this first-in-class pharmaceutical product. These included developing (a) a chemically stabilized protein, (b) a dry powder formulation exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd8ebd7dc4da1098b168252ffb9cded
https://pubmed.ncbi.nlm.nih.gov/16386095
https://pubmed.ncbi.nlm.nih.gov/16386095
Publisher Summary The intrinsic insoluble nature of protein deposits (as in amorphous aggregates, inclusion bodies, amyloid fibrils, etc.) places severe restrictions on the availability of methods required for ascertaining the structure of the materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::986b751ce8689853ef440df9cbaad019
https://doi.org/10.1016/s0076-6879(99)09038-2
https://doi.org/10.1016/s0076-6879(99)09038-2
Publikováno v:
Biochemistry. 33(6)
Fourier transform-infrared (FTIR) spectroscopy has been used to test for the presence of nonrandom structure in thermally denatured ribonuclease A (RNase A) at pH* 2.0 (uncorrected pH measured in D2O). The amide I spectral region of the native and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb093932fb1b941b5d886039841e344f
https://pubmed.ncbi.nlm.nih.gov/8312253
https://pubmed.ncbi.nlm.nih.gov/8312253
Autor:
Steven Gray, Gregory S. Steeno, Romain Taniere, Sangita Seshadri, Stevenson Cynthia L, Joann M. Parker, Jennifer S. de Groot, Carlos Schuler, Jacqueline D. Schumacher, Harper Nancy Jane, Adrian E. Smith, May Wang, David B. Bennett, Negar Sadrzadeh
Publikováno v:
Diabetes Technology & Therapeutics. 9:S-16
The Exubera system (Pfizer, New York, NY/Nektar Therapeutics, San Carlos, CA) is an integration of five major new technologies: protein formulation, powder processing, powder filling, drug packaging, and delivery device. The product provides a simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78893bdca6512648e3e93fc2d469138
https://doi.org/10.1089/dia.2007.0222
https://doi.org/10.1089/dia.2007.0222
Autor:
Nancy J. Harper, Steven Gray, Jennifer De Groot, Joann M. Parker, Negar Sadrzadeh, Carlos Schuler, Jacqueline D. Schumacher, Sangita Seshadri, Adrian E. Smith, Gregory S. Steeno, Cynthia L. Stevenson, Romain Taniere, May Wang, David B. Bennett
Publikováno v:
Diabetes Technology & Therapeutics; Jun2007, Vol. 9 Issue 0, pS-16-S-27, 12p
Autor:
Steven White, David B. Bennett, Scot Cheu, Patrick W. Conley, Donald B. Guzek, Steven Gray, John Howard, Richard Malcolmson, Joann M. Parker, Phil Roberts, Negar Sadrzadeh, Jacqueline D. Schumacher, Sangita Seshadri, Gregory W. Sluggett, Cynthia L. Stevenson, Nancy J. Harper
Publikováno v:
Diabetes Technology & Therapeutics; Dec2005, Vol. 7 Issue 6, p896-906, 11p
Publikováno v:
Folding and Design. (1):19-25
Background : Although small proteins may fold in an apparent two-state manner, most studies of protein folding reveal transient intermediates. The ‘molten globule' has been proposed to be a general intermediate in protein folding. Relatively little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc96e42eac701ee338f18be1d8d4a846