Verification of Reference Interval of Thyroid Hormones With Manual and Automated Indirect Approaches: Comparison of Hoffman, KOSMIC and refineR Methods.

Autor: Agaravatt A; Department of Biochemistry, PDU (Pandit Deendayal Upadhyay) Medical College, Rajkot, IND., Kansara G; Department of Biochemistry, Dr. Kiran C. Patel Medical College and Research Institute, Bharuch, IND., Khubchandani A; Department of Biochemistry, BJ (Byramjee Jeejeebhoy) Medical College, Ahmedabad, IND., Sanghani H; Department of Biochemistry, GMERS (Gujarat Medical Education & Research Society) Medical College, Morbi, IND., Patel S; Department of Biochemistry, Government Medical College, Surat, IND., Parchwani D; Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, IND.

Publikováno v: Cureus [Cureus] 2023 May 15; Vol. 15 (5), pp. e39066. Date of Electronic Publication: 2023 May 15 (Print Publication: 2023).

HPR45 Analysis of Alternative Access Routes and Time to Access for Paediatric Indication Expansions with Consideration of Regulatory, Pricing, and Access Incentives

Autor: Dorey, J., Minisker, B., Dehnen, J., Clark, J., Patel, B., Hodder, M., Sanghani, H.

Publikováno v: In Value in Health June 2023 26(6) Supplement:S219-S219

Use of patient-derived cellular models to investigate the mechanistic basis of circadian dysfunctions and chronomodulatory drugs in bipolar disorder

Autor: Sanghani, H

Bipolar disorder is a highly incapacitating neuropsychiatric disorder, where patients exhibit cycling episodes of mania and depression. In addition to these characteristics, sleep and circadian rhythm disruptions are frequently observed through chang

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https://ora.ox.ac.uk/objects/uuid:40b44a32-e3ac-4823-a245-e75678f26685

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells.

Autor: Zhuang X; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tsukuda S; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Wrensch F; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France., Wing PAC; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Schilling M; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harris JM; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Borrmann H; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Morgan SB; Respiratory Medicine Unit and National Institute for Health Research Oxford Biomedical Research Centre, Nuffield Department of Medicine, Experimental Medicine, University of Oxford, UK., Cane JL; Respiratory Medicine Unit and National Institute for Health Research Oxford Biomedical Research Centre, Nuffield Department of Medicine, Experimental Medicine, University of Oxford, UK., Mailly L; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France., Thakur N; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, UK., Conceicao C; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, UK., Sanghani H; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Heydmann L; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France., Bach C; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France., Ashton A; Department of Pharmacology, University of Oxford, Oxford, UK., Walsh S; Department of Pharmacology, University of Oxford, Oxford, UK., Tan TK; MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital, Oxford 17 OX3 9DS, UK., Schimanski L; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital, Oxford 17 OX3 9DS, UK., Huang KA; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University and Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Schuster C; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France., Watashi K; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan., Hinks TSC; Respiratory Medicine Unit and National Institute for Health Research Oxford Biomedical Research Centre, Nuffield Department of Medicine, Experimental Medicine, University of Oxford, UK., Jagannath A; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Vausdevan SR; Department of Pharmacology, University of Oxford, Oxford, UK., Bailey D; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, UK., Baumert TF; Université de Strasbourg, Strasbourg, France and INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France.; Pole Hépato-digestif, IHU, Hopitaux Universitaires de Strasbourg, Strasbourg, France., McKeating JA; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Publikováno v: IScience [iScience] 2021 Oct 22; Vol. 24 (10), pp. 103144. Date of Electronic Publication: 2021 Sep 16.

Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice.

Autor: Jagannath A; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK. aarti.jagannath@ndcn.ox.ac.uk., Varga N; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Dallmann R; Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK., Rando G; Department of Molecular Biology, University of Geneva, Geneva 4, Switzerland., Gosselin P; Department of Molecular Biology, University of Geneva, Geneva 4, Switzerland., Ebrahimjee F; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Taylor L; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Mosneagu D; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Stefaniak J; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Walsh S; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Palumaa T; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Di Pretoro S; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Sanghani H; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Wakaf Z; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Churchill GC; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Galione A; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK., Peirson SN; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK., Boison D; Department of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA., Brown SA; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Foster RG; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK. russell.foster@eye.ox.ac.uk., Vasudevan SR; Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK. sridhar.vasudevan@pharm.ox.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2021 Apr 09; Vol. 12 (1), pp. 2113. Date of Electronic Publication: 2021 Apr 09.