Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sanghamitra Sahoo"'
Autor:
Sanghamitra Sahoo, Daniel N Meijles, Imad Al Ghouleh, Manuj Tandon, Eugenia Cifuentes-Pagano, John Sembrat, Mauricio Rojas, Elena Goncharova, Patrick J Pagano
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0153780 (2016)
BACKGROUND:Vascular hyperproliferative disorders are characterized by excessive smooth muscle cell (SMC) proliferation leading to vessel remodeling and occlusion. In pulmonary arterial hypertension (PAH), SMC phenotype switching from a terminally dif
Externí odkaz:
https://doaj.org/article/6d9e90dddcb1477581c7f181d36ce920
Autor:
Hare Krushna Tola, Priyadarshini Sanghamitra Sahoo, Bana Bihari Mohanty, Laxmi Kanta Mishra, Ram Naresh Prasad Choudhary
Publikováno v:
Ferroelectrics. 587:150-157
Autor:
Usha R. Pendurthi, L. Vijaya Mohan Rao, Steven Idell, Torry A. Tucker, Sanghamitra Sahoo, Shiva Keshava
The procoagulant protein tissue factor (F3) is a powerful growth promoter in many tumors, but its mechanism of action is not well understood. More generally, it is unknown whether hemostatic factors expressed on tumor cells influence tissue factor-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254e9d0b4af1fc3d0e2e2f0d485d4388
https://doi.org/10.1158/0008-5472.c.6504674
https://doi.org/10.1158/0008-5472.c.6504674
Autor:
Usha R. Pendurthi, L. Vijaya Mohan Rao, Steven Idell, Torry A. Tucker, Sanghamitra Sahoo, Shiva Keshava
Supplementary File PDF 277K, Supplementary Methods: Includes additional details of reagents and methodology, and references. Supplementary Figure 1: Effect of FVIIa and thrombin on cell proliferation of wild-type REN, TF- or PAR1- knocked-down REN MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cb6172e32bab062ce05115f6568b43
https://doi.org/10.1158/0008-5472.22396844.v1
https://doi.org/10.1158/0008-5472.22396844.v1
Autor:
Elena A. Goncharova, Yao Li, Sanghamitra Sahoo, Mauricio Rojas, Daniel de Jesus, Patrick J. Pagano, John Sembrat, Adam C. Straub, Eugenia Cifuentes-Pagano
Publikováno v:
Am J Physiol Heart Circ Physiol
Pulmonary arterial hypertension (PAH) is a fatal cardiopulmonary disease characterized by increased vascular cell proliferation with apoptosis resistance and occlusive remodeling of the small pulmonary arteries. The Notch family of proteins subserves
Autor:
Adam C. Straub, Damir Kračun, Eugenia Cifuentes-Pagano, Evan DeVallance, Patrick J. Pagano, Mohamed El Massry, Christopher M Dustin, Aditi U. Gurkar, Toren Finkel, Cynthia St. Hilaire, Yao Li, Shuai Yuan, Christian J Goossen, Sanghamitra Sahoo
Publikováno v:
Proc Natl Acad Sci U S A
In an aging population, intense interest has shifted toward prolonging health span. Mounting evidence suggests that cellular reactive species are propagators of cell damage, inflammation, and cellular senescence. Thus, such species have emerged as pu
Publikováno v:
Journal of Datta Meghe Institute of Medical Sciences University. 17:416
Autor:
Patrick J. Pagano, Sanghamitra Sahoo
Publikováno v:
Hypertension. 74
Background: Communication among various cell types is known to play a pivotal role in PAH. Endothelial cell (EC)-derived exosomes have emerged as important mediators of intercellular communication and are known to influence the function of recipient
Publikováno v:
Clinical Science. 130:317-335
Reactive oxygen species (ROS) and oxidative stress have long been linked to aging and diseases prominent in the elderly such as hypertension, atherosclerosis, diabetes and atrial fibrillation (AF). NADPH oxidases (Nox) are a major source of ROS in th
Publikováno v:
Hypertension. 72
Background: Pulmonary arterial hypertension (PAH) develops when pulmonary vascular resistance rises sharply, leading to right heart failure and death. Most studies have focused on attenuating lung vessel constriction; however, little is known about t