Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sangeun Chae"'
Autor:
Eunmi Jung, Ji-Na You, Young-Jae Yang, Dae-Yon Lee, Tae-Sung Koo, Nam Sook Kang, Sangeun Chae, Kim Yun Ki, Dae-Hyuck Kang, Jong-Woo Jeong, So Jung Son, Myeong Hwi Lee, Jeonghee Ryu, Woosub Yoon, Anand Balupuri, Hyunjin Kwon
Publikováno v:
European journal of medicinal chemistry. 148
Autotaxin (ATX) is a potential target for the treatment of various cancers. A new series of ATX inhibitors was rationally designed and synthesized based on our previous study. Biological evaluation and structure-activity relationship (SAR) of this se
Autor:
Jeonghee Ryu, Myeong Hwi Lee, Kim Yun Ki, Eunmi Jung, Nam Sook Kang, Anand Balupuri, Sangeun Chae, Dae-Yon Lee
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(17)
The autotaxin-lysophophatidic acid (ATX-LPA) signaling pathway is involved in several human diseases such as cancer, autoimmune diseases, inflammatory diseases neurodegenerative diseases and fibrotic diseases. Herein, a series of 4-phenyl-thiazole ba