Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sangeetha Purushotham"'
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144621 (2015)
Interaction among crystallins is required for the maintenance of lens transparency. Deamidation is one of the most common post-translational modifications in crystallins, which results in incorrect interaction and leads to aggregate formation. Variou
Externí odkaz:
https://doaj.org/article/a7395453ee914001918a0eb39138022e
Autor:
Norbert Schormann, Manisha Patel, Luke Thannickal, Sangeetha Purushotham, Ren Wu, Joshua L. Mieher, Hui Wu, Champion Deivanayagam
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 79:119-127
Streptococcus mutans, found in the human oral cavity, is a significant contributor to the pathogenesis of dental caries. This bacterium expresses three genetically distinct types of glucosyltransferases named GtfB (GTF-I), GtfC (GTF-SI) and GtfD (GTF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3287b5a6e4b7c907496cdd0f51ab6afe
https://doi.org/10.1107/s2053230x23003199
https://doi.org/10.1107/s2053230x23003199
Autor:
Norbert Schormann, Hui Wu, Champion Deivanayagam, Manisha Patel, Sangeetha Purushotham, Joshua L. Mieher
Publikováno v:
Acta Crystallogr D Struct Biol
Streptococcus gordonii is a member of the viridans streptococci and is an early colonizer of the tooth surface. Adherence to the tooth surface is enabled by proteins present on the S. gordonii cell surface, among which SspB belongs to one of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badf38ae960e9bfbe1694ae49ac2c7f0
https://europepmc.org/articles/PMC8411976/
https://europepmc.org/articles/PMC8411976/
Autor:
Sangeetha Purushotham, Norbert Schormann, Jessica Scoffield, Champion Deivanayagam, Hui Wu, Ren Wu, Manisha Patel, Joshua L. Mieher
Publikováno v:
J Bacteriol
Streptococcus intermedius, an oral commensal bacterium, is found at various sites, including subgingival dental plaque, purulent infections, and cystic fibrosis lungs. Oral streptococci utilize proteins on their surface to adhere to tissues and/or su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe9817ded062f39fb2d95f333d77c3a
https://pubmed.ncbi.nlm.nih.gov/34339301
https://pubmed.ncbi.nlm.nih.gov/34339301
Autor:
Thapa, Narendra, Hong, Hai-Yan, Sangeetha, Purushotham, Kim, In-San, Yoo, Jeongsoo, Rhee, Kyehan, Oh, Goo Taeg, Kwon, Ick Chan, Lee, Byung-Heon
Publikováno v:
In Journal of Controlled Release 2008 131(1):27-33
Autor:
Champion Deivanayagam, L. Jeannine Brady, Sangeetha Purushotham, Richard N. Besingi, Alejandro Avilés-Reyes, Jacqueline Abranches, José A. Lemos, Irlan Almeida Freires
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Protein glycosylation has been described as the most abundant and complex post-translational modification occurring in nature. Recent studies have enhanced our view of how this modification occurs in bacteria highlighting the role of protein glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e5125ff905baf71d675ced658000d6
http://link.springer.com/article/10.1038/s41598-018-23170-3
http://link.springer.com/article/10.1038/s41598-018-23170-3
Publikováno v:
In Experimental Gerontology 2005 40(10):820-828
Autor:
Haripriya, Dayalan, Sangeetha, Purushotham, Kanchana, Amarnath, Balu, Muthaiya, Panneerselvam, Chinnakannu *
Publikováno v:
In Experimental Gerontology 2005 40(3):129-135
Autor:
Champion Deivanayagam, Matthew R. Larson, Sangeetha Purushotham, Joshua L. Mieher, Norbert Schormann, Hui Wu, Ren Wu, Kanagalaghatta R. Rajashankar
Publikováno v:
Infection and immunity. 86(7)
The high-resolution structure of glucan binding protein C (GbpC) at 1.14 Å, a sucrose-dependent virulence factor of the dental caries pathogen Streptococcus mutans , has been determined. GbpC shares not only structural similarities with the V regio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd9269061455aedb4ad4562f4e8653d
https://pubmed.ncbi.nlm.nih.gov/29685986
https://pubmed.ncbi.nlm.nih.gov/29685986
Publikováno v:
Journal of Biological Chemistry. 289:21877-21887
Oral streptococci adhere to tooth-immobilized glycoprotein 340 (GP340) via the surface protein antigen I/II (AgI/II) and its homologs as the first step in pathogenesis. Studying this interaction using recombinant proteins, we observed that calcium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014b68edf19eb6528302a7e0b70bb19f
https://doi.org/10.1074/jbc.m114.565507
https://doi.org/10.1074/jbc.m114.565507