Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sangbin, Lim"'
Autor:
Seol Hwa Shin, Eun Jin Ju, Jin Park, Eun Jung Ko, Mi Ri Kwon, Hye Won Lee, Ga Won Son, Yun-Yong Park, Yeon Joo Kim, Si Yeol Song, Sangkwang Lee, Beom Seok Seo, Jin-A Song, Sangbin Lim, Doohwan Jung, Sunyoung Kim, Hyangsook Lee, Seok Soon Park, Seong-Yun Jeong, Eun Kyung Choi
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The B7-H3 protein, encoded by the CD276 gene, is a member of the B7 family of proteins and a transmembrane glycoprotein. It is highly expressed in various solid tumors, such as lung and breast cancer, and has been associated with
Externí odkaz:
https://doaj.org/article/143e4bef18f04341876c841b9c2dc509
Autor:
Sun Min Lim, San-Duk Yang, Sangbin Lim, Seong Gu Heo, Stetson Daniel, Aleksandra Markovets, Rafati Minoo, Kyoung-Ho Pyo, Mi Ran Yun, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Introduction: Osimertinib is a third-generation EGFR tyrosine kinase inhibitor (TKI) that is approved for the use of EGFR -mutant non-small cell lung cancer (NSCLC) patients. In this study, we investigated the acquired resistance mechanisms in NSCLC
Externí odkaz:
https://doaj.org/article/2422d3288270447897efe41264d6b211
Autor:
Chun‐Bong Synn, Sung Eun Kim, Hee Kyu Lee, Min‐Hwan Kim, Jae Hwan Kim, Ji Min Lee, Ha Ni Jo, Wongeun Lee, Dong Kwon Kim, Youngseon Byeon, Young Seob Kim, Mi Ran Yun, Chae‐Won Park, Jiyeon Yun, Sangbin Lim, Seong Gu Heo, San‐Duk Yang, Eun Ji Lee, Seul Lee, Hunmi Choi, You Won Lee, Jae Seok Cho, Do Hee Kim, Sungho Park, Jung‐Ho Kim, Yewon Choi, Sung Sook Lee, Beung‐Chul Ahn, Chang Gon Kim, Sun Min Lim, Min Hee Hong, Hye Ryun Kim, Kyoung‐Ho Pyo, Byoung Chul Cho
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti‐tumor and anti‐metastatic activities of SKI‐G‐801, a sma
Externí odkaz:
https://doaj.org/article/2810ccf729dc4cf68402dc5c21aa1ea6
Autor:
Sun Min Lim, MD, PhD, San-Duk Yang, PhD, Sangbin Lim, PhD, Hyo Sup Shim, MD, PhD, Byoung Chul Cho, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 6, Pp 100180- (2021)
Introduction: MET amplification is a frequently observed mechanism of resistance to osimertinib, and coinhibition strategy of MET and EGFR revealed promising results in recent clinical trials. Nevertheless, acquired resistance mechanisms to combined
Externí odkaz:
https://doaj.org/article/da7d122899ce4d5ba8b27126d47066e9
Autor:
Paul D. Smith, Byoung Chul Cho, Darren A.E. Cross, Matthew J. Martin, Jelena Urosevic, Jonathan Orme, Afshan Ahmed, Sue Bickerton, Sangbin Lim, Nicolas Floc'h
Osimertinib is an oral, third-generation, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that selectively inhibits both EGFR-TKI–sensitizing and EGFR T790M–resistance mutations with lower activity against wild-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acafb00ba8445e6d36ce8a082190e48
https://doi.org/10.1158/1535-7163.c.6541987
https://doi.org/10.1158/1535-7163.c.6541987
Autor:
Paul D. Smith, Byoung Chul Cho, Darren A.E. Cross, Matthew J. Martin, Jelena Urosevic, Jonathan Orme, Afshan Ahmed, Sue Bickerton, Sangbin Lim, Nicolas Floc'h
Supplementary Figure 1: Osimertinib monotherapy induce tumor growth inhibition in a NSCLC EGFR G719A;S768I mutation PDX model in vivo. Supplementary Figure 2: Osimertinib as monotherapy induce a stronger inhibition of the level of pEGFR and the downs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502e1342531d2b12eebb53e23045899
https://doi.org/10.1158/1535-7163.22518550
https://doi.org/10.1158/1535-7163.22518550
Autor:
Ming Tan, Laurie B. Owen, Oystein Fodstad, Ming Zhou, Luciana Madeira da Silva, Joshua B. Phillips, Sangbin Lim
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59811368ed7606ac8975e75876c71a1b
https://doi.org/10.1158/0008-5472.22416621
https://doi.org/10.1158/0008-5472.22416621
Autor:
Ming Tan, Laurie B. Owen, Oystein Fodstad, Ming Zhou, Luciana Madeira da Silva, Joshua B. Phillips, Sangbin Lim
With the recent successes in immuno-oncology, renewed interest in the role of immune checkpoint modulators, such as the B7 family proteins, has escalated. The immune checkpoint proteins play a crucial role in the regulation of cellular immunity; howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b8eba0edb19efa7bddc7afe3bfb1f1
https://doi.org/10.1158/0008-5472.c.6509601.v1
https://doi.org/10.1158/0008-5472.c.6509601.v1
Autor:
Ming Tan, Oystein Fodstad, Gary A. Piazza, Wensheng Lin, Yifeng Lin, Steven McClellan, Tung Vu, David C. Schmitt, Joshua B. Phillips, Zixing Liu, Ritu Arora, Luciana Madeira da Silva, Hao Liu, Sangbin Lim
B7-H3 is a member of B7 family of immunoregulatory transmembrane glycoproteins expressed by T cells. While B7-H3 overexpression is associated with poor outcomes in multiple cancers, it also has immune-independent roles outside T cells and its precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064abd0554c56d9595caad8a2d475c62
https://doi.org/10.1158/0008-5472.c.6508131
https://doi.org/10.1158/0008-5472.c.6508131
Autor:
Ming Tan, Oystein Fodstad, Gary A. Piazza, Wensheng Lin, Yifeng Lin, Steven McClellan, Tung Vu, David C. Schmitt, Joshua B. Phillips, Zixing Liu, Ritu Arora, Luciana Madeira da Silva, Hao Liu, Sangbin Lim
Fig. S1: Glucose uptake and lactate production in B7-H3 knockdown Fig. S2: Growth inhibition W/O B7-H3 Fig S3: Proliferation assay in glucose deprivation. Fig. S4: Expression in B7-H3 knockdown w/o CoCl2. Fig. S5: mRNA levels. Fig. S6: Reduction of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09eb9b21202d1b0db830f93ef424dd2e
https://doi.org/10.1158/0008-5472.22411032.v1
https://doi.org/10.1158/0008-5472.22411032.v1