Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sangappa B Chadchan"'
Autor:
Sangappa B. Chadchan, Pooja Popli, Zian Liao, Eryk Andreas, Michelle Dias, Tianyuan Wang, Stephanie J. Gunderson, Patricia T. Jimenez, Denise G. Lanza, Rainer B. Lanz, Charles E. Foulds, Diana Monsivais, Francesco J. DeMayo, Hari Krishna Yalamanchili, Emily S. Jungheim, Jason D. Heaney, John P. Lydon, Kelle H. Moley, Bert W. O’Malley, Ramakrishna Kommagani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cellular responses to the steroid hormones, estrogen (E2), and progesterone (P4) are governed by their cognate receptor’s transcriptional output. However, the feed-forward mechanisms that shape cell-type-specific transcriptional fulcrums f
Externí odkaz:
https://doaj.org/article/116dab8ea7be413e937452d604e585f3
Autor:
Sangappa B. Chadchan, Sumanta K. Naik, Pooja Popli, Chandni Talwar, Satwikreddy Putluri, Chandrasekhar R. Ambati, Michael A. Lint, Andrew L. Kau, Christina L. Stallings, Ramakrishna Kommagani
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Endometriosis is a pathological condition of the female reproductive tract characterized by the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between the age 15 and 49 in the USA. However, currently there is n
Externí odkaz:
https://doaj.org/article/186dd069baa643a5b739844da283a088
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Retinoic acid (RA) signaling has long been speculated to regulate embryo implantation, because many enzymes and proteins responsible for maintaining RA homeostasis and transducing RA signals are tightly regulated in the endometrium during this critic
Externí odkaz:
https://doaj.org/article/ab030f8cdc5a43bd97c9a0b13d3c37b5
Autor:
Sangappa B. Chadchan, Vineet K. Maurya, Gwendalyn L. Krekeler, Emily S. Jungheim, Ramakrishna Kommagani
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Up to 30% of women experience early miscarriage due to impaired decidualization. For implantation to occur, the uterine endometrial stromal fibroblast-like cells must differentiate into decidual cells, but the genes required for decidualization have
Externí odkaz:
https://doaj.org/article/61c56eb7b45e4b36b81f604491f728ee
Publikováno v:
J Mol Endocrinol
The gut microbiome is considered an endocrine organ that can influence distant organs and associated biological pathways. Recent advances suggest that gut microbial homeostasis is essential for reproductive health and that perturbations in the gut mi
Autor:
Pooja Popli, Suni Tang, Sangappa B. Chadchan, Chandni Talwar, Edmund B. Rucker, Xiaoming Guan, Diana Monsivais, John P. Lydon, Christina L. Stallings, Kelle H. Moley, Ramakrishna Kommagani
Publikováno v:
Developmental Cell. 58:885-897.e4
Publikováno v:
Biology of Reproduction
The coronavirus disease 2019 (COVID-19) first appeared in December 2019 and rapidly spread throughout the world. The SARS-CoV-2 virus enters the host cells by binding to the angiotensin-converting enzyme 2 (ACE2). Although much of the focus is on res
Autor:
Pooja Popli, Sangappa B. Chadchan, Suni Tang, Edmund B. Rucker III, Xiaoming Guan, Diana Monsivais, John P. Lydon, Kelle H. Moley, Ramakrishna Kommagani
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Biology of Reproduction
bioRxiv
bioRxiv
STUDY QUESTIONIs SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE 2) expressed in the human endometrium during the menstrual cycle, and does it participate in endometrial decidualization?SUMMARY ANSWERACE2 protein is highly expressed in huma
Autor:
Tae Hoon Kim, Pooja Popli, Ramakrishna Kommagani, Obi L. Griffith, Megan Richters, Eric Tycksen, Sangappa B Chadchan, Premal H. Thaker, Malachi Griffith
Publikováno v:
Cell Death and Disease, Vol 11, Iss 10, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Although endometrial cancer is the most common cancer of the female reproductive tract, we have little understanding of what controls endometrial cancer beyond the transcriptional effects of steroid hormones such as estrogen. As a result, we have lim