Zobrazeno 1 - 10
of 41
pro vyhledávání: '"SangYoon Chung"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Membrane protein biogenesis poses acute challenges to protein homeostasis, and how they are selectively escorted to the target membrane is not well understood. Here we address this question in the guided-entry-of-tail-anchored protein (GET)
Externí odkaz:
https://doaj.org/article/1414326d639f4a7cade19c8ee046f753
Autor:
Antonino Ingargiola, Eitan Lerner, SangYoon Chung, Francesco Panzeri, Angelo Gulinatti, Ivan Rech, Massimo Ghioni, Shimon Weiss, Xavier Michalet
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175766 (2017)
We describe an 8-spot confocal setup for high-throughput smFRET assays and illustrate its performance with two characteristic experiments. First, measurements on a series of freely diffusing doubly-labeled dsDNA samples allow us to demonstrate that d
Externí odkaz:
https://doaj.org/article/1f62c7dddb844603ae47db1aaf3add65
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160716 (2016)
Single-molecule Förster Resonance Energy Transfer (smFRET) allows probing intermolecular interactions and conformational changes in biomacromolecules, and represents an invaluable tool for studying cellular processes at the molecular scale. smFRET e
Externí odkaz:
https://doaj.org/article/6899e744189044e7adef5ae502cb0b0b
Autor:
Shu-ou Shan, SangYoon Chung, Shimon Weiss, Sowmya Chandrasekar, Woo Jun Shim, Yumeng Liu, Un Seng Chio
Publikováno v:
The Journal of cell biology, vol 220, iss 11
The guided entry of tail-anchored protein (GET) pathway, in which the Get3 ATPase delivers an essential class of tail-anchored membrane proteins (TAs) to the Get1/2 receptor at the endoplasmic reticulum, provides a conserved mechanism for TA biogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3565ba5cbf5351ebe882daaac4091941
https://resolver.caltech.edu/CaltechAUTHORS:20211022-170110641
https://resolver.caltech.edu/CaltechAUTHORS:20211022-170110641
Publikováno v:
Biophysical Journal. 121:359a-360a
Autor:
Yu-Hsien Hwang Fu, Hao-Hsuan Hsieh, Nenad Ban, Daniel Boehringer, Ahmad Jomaa, Sowmya Chandrasekar, Shu-ou Shan, Simone Mattei, SangYoon Chung, Xuemeng Sun, Shimon Weiss, Ruilin Qian, Jae Ho Lee, Xiaotian Bi
Publikováno v:
Science Advances
Science advances, vol 7, iss 21
Science Advances, 7 (21)
Science advances, vol 7, iss 21
Science Advances, 7 (21)
The conserved signal recognition particle (SRP) cotranslationally delivers ~30% of the proteome to the eukaryotic endoplasmic reticulum (ER). The molecular mechanism by which eukaryotic SRP transitions from cargo recognition in the cytosol to protein
Autor:
Yu-Hsien Hwang Fu, Shimon Weiss, Jae Ho Lee, SangYoon Chung, Ruilin Qian, Xuemeng Sun, Shu-ou Shan
Signal recognition particle (SRP) is a universally conserved targeting machine that couples the synthesis of ~30% of the proteome to their proper membrane localization1,2. In eukaryotic cells, SRP recognizes translating ribosomes bearing hydrophobic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0601635e48c1edb53d44e11e360d4d18
https://doi.org/10.1101/2020.01.07.897827
https://doi.org/10.1101/2020.01.07.897827
Autor:
Jonathan A. White, Eitan Lerner, Xavier Michalet, SangYoon Chung, Antonino Ingargiola, Maya Segal, Aaron M. Streets, Shimon Weiss
Publikováno v:
Methods
Single-molecule Förster resonance energy transfer (smFRET) is a powerful technique for nanometer-scale studies of single molecules. Solution-based smFRET, in particular, can be used to study equilibrium intra- and intermolecular conformations, bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5813f3f1fa9a10b47d355c15dda1ad
Publikováno v:
Cell reports, vol 26, iss 1
Chio, Un Seng; Chung, SangYoon; Weiss, Shimon; & Shan, Shu-Ou. (2019). A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting.. Cell reports, 26(1), 37-44.e7. doi: 10.1016/j.celrep.2018.12.035. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2822602h
Chio, Un Seng; Chung, SangYoon; Weiss, Shimon; & Shan, Shu-Ou. (2019). A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting.. Cell reports, 26(1), 37-44.e7. doi: 10.1016/j.celrep.2018.12.035. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2822602h
Molecular chaperones play key roles in maintaining cellular proteostasis. In addition to preventing client aggregation, chaperones often relay substrates within a network while preventing off-pathway chaperones from accessing the substrate. Here we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628363f858657cb1029dd776d8b79163
https://europepmc.org/articles/PMC6689467/
https://europepmc.org/articles/PMC6689467/
Autor:
Charles M. Knobler, Logan Wilson Grimaud, Shimon Weiss, SangYoon Chung, Yazan Alhadid, Yan Jin, William M. Gelbart, Eitan Lerner, Soohong Kim, Irina X. Zhang
Publikováno v:
Chung, SangYoon; Lerner, Eitan; Jin, Yan; Kim, Soohong; Alhadid, Yazan; Grimaud, Logan Wilson; et al.(2018). The effect of macromolecular crowding on single-round transcription by Escherichia coli RNA polymerase.. Nucleic acids research, 47(3), 1440-1450. doi: 10.1093/nar/gky1277. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1wb7t026
Nucleic Acids Research
Nucleic acids research, vol 47, iss 3
Nucleic Acids Research
Nucleic acids research, vol 47, iss 3
Previous works have reported significant effects of macromolecular crowding on the structure and behavior of biomolecules. The crowded intracellular environment, in contrast to in vitro buffer solutions, likely imparts similar effects on biomolecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf884217e653549599ad6924387e9248
http://www.escholarship.org/uc/item/1wb7t026
http://www.escholarship.org/uc/item/1wb7t026