Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sang-hyuck Lee"'
Autor:
Su-Jin Kim, Tae-Bong Kang, Dong-Hyuk Kim, Minho Keum, Sung-Hee Lee, Ji-Hun Kim, Sang-Hyuck Lee, Jihoon Kim, Hyuk-Jung Kweon, Jae-Won Park, Beom-Jun Kim, Hyung-Sik Won
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1588 (2022)
Natural antimicrobial peptides (AMPs) are multifunctional host defense peptides (HDPs) that are valuable for various therapeutic applications. In particular, natural and artificial AMPs with dual antibacterial immunomodulatory functions emerged as pr
Externí odkaz:
https://doaj.org/article/711c07bf8cab407db2fb0311a2a4cba3
Autor:
Christos Tziotzios, Christos Petridis, Nick Dand, Chrysanthi Ainali, Jake R. Saklatvala, Venu Pullabhatla, Alexandros Onoufriadis, Rashida Pramanik, David Baudry, Sang Hyuck Lee, Kristie Wood, Lu Liu, Seth Seegobin, Gregory A. Michelotti, Su M. Lwin, Evangelos A. A. Christou, Charles J. Curtis, Emanuele de Rinaldis, Alka Saxena, Susan Holmes, Matthew Harries, Ioulios Palamaras, Fiona Cunningham, Gregory Parkins, Manjit Kaur, Paul Farrant, Andrew McDonagh, Andrew Messenger, Jennifer Jones, Victoria Jolliffe, Iaisha Ali, Michael Ardern-Jones, Charles Mitchell, Nigel Burrows, Ravinder Atkar, Cedric Banfield, Anton Alexandroff, Caroline Champagne, Hywel L. Cooper, Sergio Vañó-Galván, Ana Maria Molina-Ruiz, Nerea Ormaechea Perez, Girish K. Patel, Abby Macbeth, Melanie Page, Alyson Bryden, Megan Mowbray, Shyamal Wahie, Keith Armstrong, Nicola Cooke, Mark Goodfield, Irene Man, David de Berker, Giles Dunnill, Anita Takwale, Archana Rao, Tee-Wei Siah, Rodney Sinclair, Martin S. Wade, Ncoza C. Dlova, Jane Setterfield, Fiona Lewis, Kapil Bhargava, Niall Kirkpatrick, Xavier Estivill, Catherine M. Stefanato, Carsten Flohr, Timothy Spector, Fiona M. Watt, Catherine H. Smith, Jonathan N. Barker, David A. Fenton, Michael A. Simpson, John A. McGrath
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Frontal fibrosing alopecia (FFA) features lichenoid cutaneous inflammation and scarring hair loss. Here, Tziotzios et al. identify four genetic loci associated with FFA by GWAS followed by Bayesian fine-mapping, co-localisation and HLA imputation whi
Externí odkaz:
https://doaj.org/article/2a42af5d272646528b4002af71d71088
Autor:
Christos Petridis, Alexander A. Navarini, Nick Dand, Jake Saklatvala, David Baudry, Michael Duckworth, Michael H. Allen, Charles J. Curtis, Sang Hyuck Lee, A. David Burden, Alison Layton, Veronique Bataille, Andrew E. Pink, The Acne Genetic Study Group, Isabelle Carlavan, Johannes J. Voegel, Timothy D. Spector, Richard C. Trembath, John A. McGrath, Catherine H. Smith, Jonathan N. Barker, Michael A. Simpson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Acne vulgaris is a chronic inflammation of the skin, the genetic basis of which is incompletely understood. Here, Petridis et al. perform GWAS and meta-analysis for acne in 26,722 individuals and identify 12 novel risk loci that implicate structure a
Externí odkaz:
https://doaj.org/article/452ea8192e3a4a489db21942afed2d37
Autor:
Oyesola O. Ojewunmi, Titilope A. Adeyemo, Ajoke I. Oyetunji, Bassey Inyang, Afolashade Akinrindoye, Baraka S. Mkumbe, Kate Gardner, Helen Rooks, John Brewin, Hamel Patel, Sang-Hyuck Lee, Raymond Chung, Sara Rashkin, Guolian Kang, Reuben Chianumba, Raphael Sangeda, Liberata Mwita, Hezekiah Isa, Uche-Nnebe Agumadu, Rosemary Ekong, Jamilu A. Faruk, Bello Y. Jamoh, Niyi M. Adebiyi, Ismail A. Umar, Abdulaziz Hassan, Christopher Grace, Anuj Goel, Baba P.D. Inusa, Mario Falchi, Siana Nkya, Julie Makani, Hafsat R. Ahmad, Obiageli Nnodu, John Strouboulis, Stephan Menzel
BackgroundThe clinical severity of sickle cell disease (SCD) is strongly influenced by the level of fetal haemoglobin (HbF) persistent in each patient. Three major HbF loci (BCL11A,HBS1L-MYB, andXmn1-HBG2) have been reported, but a considerable hidde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec5aa8af3810e908446c6f3dd1ab4d2
https://doi.org/10.1101/2023.05.16.23289851
https://doi.org/10.1101/2023.05.16.23289851
Autor:
Jessica Mundy, Christopher Hübel, Brett N. Adey, Helena L. Davies, Molly R. Davies, Jonathan R. I. Coleman, Matthew Hotopf, Gursharan Kalsi, Sang Hyuck Lee, Andrew M. McIntosh, Henry C. Rogers, Thalia C. Eley, Robin M. Murray, Evangelos Vassos, Gerome Breen
Publikováno v:
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses manic symptoms. Its utility for genetic studies of mania or bipolar traits has not been fully examined. We psychometrically compared the MDQ to self-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415c411233d622ef7b494907c26dafb8
https://pure.au.dk/portal/da/publications/genetic-examination-of-the-mood-disorder-questionnaire-and-its-relationship-with-bipolar-disorder(47ce0bc5-2e41-4bbe-89f4-fcde74c242ec).html
https://pure.au.dk/portal/da/publications/genetic-examination-of-the-mood-disorder-questionnaire-and-its-relationship-with-bipolar-disorder(47ce0bc5-2e41-4bbe-89f4-fcde74c242ec).html
Autor:
Molly R. Davies, Kiran Glen, Jessica Mundy, Abigail R. ter Kuile, Brett N. Adey, Chérie Armour, Elham Assary, Jonathan R.I. Coleman, Kimberley A. Goldsmith, Colette R. Hirsch, Matthew Hotopf, Christopher Hübel, Ian R. Jones, Gursharan Kalsi, Georgina Krebs, Andrew M. McIntosh, Geneviève Morneau-Vaillancourt, Alicia J. Peel, Kirstin L. Purves, Sang Hyuck Lee, Megan Skelton, Daniel J. Smith, David Veale, James T.R. Walters, Katherine S. Young, Johan Zvrskovec, Gerome Breen, Thalia C. Eley
Publikováno v:
Davies, M R, Glen, K, Mundy, J, Adey, B, Armour, C, Assary, E, Coleman, J, Goldsmith, K, Hirsch, C, Hotopf, M, Hübel, C, Jones, I, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A, Purves, K, Lee, S, Skelton, M, Smith, D J, Veale, D, Walters, J, Young, K, Källberg Zvrskovec, J, Breen, G & Grant, T E 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Kuile, A R T, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2022, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders (JAD) . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Kuile, A R T, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2022, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders (JAD) . https://doi.org/10.1016/j.jad.2022.11.051
BackgroundAnxiety and depressive disorders often co-occur and the order of their emergence may be associated with different clinical outcomes. However, minimal research has been conducted on anxiety-anxiety comorbidity. This study examined factors as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8507ef0fe5b84d714c262376017724af
https://kclpure.kcl.ac.uk/en/publications/6be14141-2856-46f3-8145-6b176d798a3b
https://kclpure.kcl.ac.uk/en/publications/6be14141-2856-46f3-8145-6b176d798a3b
Autor:
Dina Monssen, Helena L Davies, Shannon Bristow, Saakshi Kakar, Susannah C B Curzons, Molly R Davies, Zain Ahmad, John R Bradley, Steven Bright, Jonathan R I Coleman, Kiran Glen, Matthew Hotopf, Emily J Kelly, Abigail R Ter Kuile, Chelsea Mika Malouf, Gursharan Kalsi, Nathalie Kingston, Monika McAtarsney-Kovacs, Jessica Mundy, Alicia J Peel, Alish B Palmos, Henry C Rogers, Megan Skelton, Brett N Adey, Sang Hyuck Lee, Hope Virgo, Tom Quinn, Tom Price, Johan Zvrskovec, Thalia C Eley, Janet Treasure, Christopher Hübel, Gerome Breen
ObjectiveThe Eating Disorders Genetics Initiative United Kingdom (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic aetiology of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f00a5ab01c32896d4b14a66d9606bef
https://doi.org/10.1101/2022.11.11.22282083
https://doi.org/10.1101/2022.11.11.22282083
Autor:
Hamel Patel, Sang‐Hyuck Lee, Gerome Breen, Stephen Menzel, Oyesola Ojewunmi, Richard J.B. Dobson
Publikováno v:
Current protocolsLiterature CitedInternet Resources. 2(4)
The Illumina genotyping microarrays generate data in image format, which is processed by the platform-specific software GenomeStudio, followed by an array of complex bioinformatics analyses that rely on various software, different programming languag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564335f09054b6ca0fe0807cd74bf826
https://pubmed.ncbi.nlm.nih.gov/35452565
https://pubmed.ncbi.nlm.nih.gov/35452565
Autor:
Abigail ter Kuile, Brittany Mitchell, Alicia Peel, Jessica Mundy, Christopher Hübel, Johan Zvrskovec, Alish Palmos, Jonathan Coleman, Molly Davies, Nick Martin, Enda M. Byrne, Sarah E. Medland, Naomi R. Wray, Brett N. Adey, Sang Hyuck Lee, Anna E. Fürtjes, Geneviève Morneau-Vaillancourt, Kirstin Purves, Megan Skelton, Matthew Hotopf, Daniel J. Smith, David Veale, Chérie Armour, Andrew McIntosh, James T.R. Walters, Ian R. Jones, Colette R. Hirsch, Gursharan Kalsi, Gerome Breen, Thalia Eley
Publikováno v:
European Neuropsychopharmacology. 63:e2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ae58d20756546dd0604138838a600e
https://doi.org/10.1016/j.euroneuro.2022.07.014
https://doi.org/10.1016/j.euroneuro.2022.07.014
Autor:
Richard Dobson, Hamel Patel, Oyesola Oyewole Ojewunmi, Gerome Breen, Sang-hyuck Lee, Stephen Menzel
BackgroundThe Illumina genotyping microarrays generate data in image format, which is processed by the platform-specific software GenomeStudio, followed by an array of complex bioinformatics analyses. This process can be time-consuming, lead to repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a066d6a291dc9ca310fcdda77980fc46
https://doi.org/10.1101/2021.07.26.453753
https://doi.org/10.1101/2021.07.26.453753