Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Sang-Taek Jung"'
Autor:
Sang Min Lee, Sung-Won Min, Hyeong Sun Kwon, Gong-Deuk Bae, Ji Hae Jung, Hye In Park, Seung Hyeon Lee, Chung Su Lim, Byoung Joon Ko, Ji Chul Lee, Sang Taek Jung
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Complement-dependent cytotoxicity (CDC), which eliminates aberrant target cells through the assembly and complex formation of serum complement molecules, is one of the major effector functions of anticancer therapeutic antibodies. In this st
Externí odkaz:
https://doaj.org/article/5b52ae50a2aa425d999e5618773732a7
Targeting TCTP sensitizes tumor to T cell-mediated therapy by reversing immune-refractory phenotypes
Autor:
Hyo-Jung Lee, Kwon-Ho Song, Se Jin Oh, Suyeon Kim, Eunho Cho, Jungwon Kim, Yun gyu Park, Kyung-Mi Lee, Cassian Yee, Seung-Hwa Song, Suhwan Chang, Jungmin Choi, Sang Taek Jung, Tae Woo Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Translationally controlled tumor protein (TCTP) regulates several cellular processes, including apoptosis, and is overexpressed in several cancer types. Here, the authors report that high levels of TCTP are associated with poor response to anti-PD-L1
Externí odkaz:
https://doaj.org/article/2e832e4f516d4e8ba956b812b9171d28
Autor:
Woo Sung Kim, Ji Hyun Kim, Jisun Lee, Su Yeon Ka, Hee Do Chae, Inji Jung, Sang Taek Jung, Jung-Hyun Na
Publikováno v:
Bioengineering, Vol 9, Iss 11, p 670 (2022)
A new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant known as Omicron has caused a rapid increase in recent global patients with coronavirus infectious disease 2019 (COVID-19). To overcome the COVID-19 Omicron variant, productio
Externí odkaz:
https://doaj.org/article/88a0f9be57b3471e9bf7de3ecf16e9e8
Autor:
Byeong Sung Lee, Yumi Lee, Jisoo Park, Bo Seok Jeong, Migyeong Jo, Sang Taek Jung, Tae Hyeon Yoo
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-13 (2019)
Abstract Background Immunotoxins consisting of a toxin from bacteria or plants and a targeting module have been developed as potent anti-cancer therapeutics. The majority of them, especially those in preclinical or clinical testing stages, are fusion
Externí odkaz:
https://doaj.org/article/2f9450c119cf408caa0a45f4cc13deba
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Protein production requires a significant amount of intracellular energy. Eliminating the flagella has been proposed to help Escherichia coli improve protein production by reducing energy consumption. In this study, the gene encoding a subunit of Flh
Externí odkaz:
https://doaj.org/article/8286aee23ea04c2dad95d98175e42035
Autor:
Ji Yeon Ha, Kwang-Jin Chun, Sanghwan Ko, Ho Won Lee, Ok Kyung Hwang, Chung Su Lim, Kyungsoo Ha, Byoung Joon Ko, Sang Taek Jung
Publikováno v:
Molecular Pharmaceutics. 20:2170-2180
Autor:
Sanghwan Ko, Man-Seok Ju, Hye-Mi Ahn, Jung-Hyun Na, Woo Hyung Ko, Migyeong Jo, Munsu Kyung, Chung Su Lim, Byoung Joon Ko, Won-Kyu Lee, Youn-Jae Kim, Sang Taek Jung
Publikováno v:
Molecular Pharmaceutics. 20:1247-1255
Endothelin receptor A (ET
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract G-protein coupled receptors (GPCRs) play indispensable physiological roles in cell proliferation, differentiation, and migration; therefore, identifying the mechanisms by which ligands bind to GPCRs is crucial for developing GPCR-targeting p
Externí odkaz:
https://doaj.org/article/a95ef854682540e9ad103939b8dbf401
Autor:
Tae Hyun Kang, Sang Taek Jung
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 382 (2020)
The constant region of immunoglobulin (Ig) G antibodies is responsible for their effector immune mechanism and prolongs serum half-life, while the fragment variable (Fv) region is responsible for cellular or tissue targeting. Therefore, antibody engi
Externí odkaz:
https://doaj.org/article/6879f4e3eeaa4faea43fa0e501297d4d
Publikováno v:
Biotechnology and Bioprocess Engineering. 26:985-992