Zobrazeno 1 - 10
of 43 231
pro vyhledávání: '"Sang-In Kim"'
Autor:
Annie Yang, Zhifang Zhang, Shyambabu Chaurasiya, Anthony K. Park, Jianming Lu, Sang-In Kim, Hannah Valencia, Yuman Fong, Yanghee Woo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100734- (2023)
Gastric cancer (GC) peritoneal metastasis (PM) is fatal without effective therapy. We investigated CF17, a new replication-competent chimeric poxvirus, against GC cell lines in vitro and PM in an aggressive GCPM mouse model. We performed viral prolif
Externí odkaz:
https://doaj.org/article/728167b8bf134834a68b049f3bd93a0f
Autor:
Zhifang Zhang, Annie Yang, Shyambabu Chaurasiya, Anthony K. Park, Sang-In Kim, Jianming Lu, Tove Olafsen, Susanne G. Warner, Yuman Fong, Yanghee Woo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 331-339 (2022)
Peritoneal carcinomatosis of gastrointestinal malignancies remains fatal. CF33-hNIS-antiPDL1, a chimeric orthopoxvirus expressing the human sodium iodide symporter (hNIS) and anti-human programmed death-ligand 1 antibody, has demonstrated robust prec
Externí odkaz:
https://doaj.org/article/b136a546a3ad407fb2d3b3567d1fefc5
Autor:
Shyambabu Chaurasiya, Annie Yang, Zhifang Zhang, Jianming Lu, Hannah Valencia, Sang-In Kim, Yanghee Woo, Suanne G. Warner, Tove Olafsen, Yuqi Zhao, Xiwei Wu, Seymour Fein, Linda Cheng, Maria Cheng, Nicholas Ede, Yuman Fong
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 102-116 (2022)
CF33-hNIS-anti-PD-L1 is an oncolytic chimeric poxvirus encoding two transgenes: human sodium iodide symporter and a single-chain variable fragment against PD-L1. Comprehensive preclinical pharmacology studies encompassing primary and secondary pharma
Externí odkaz:
https://doaj.org/article/970c8e52369d4fbd868c37193c54a126
Autor:
Sang-In Kim, Shyambabu Chaurasiya, Venkatesh Sivanandam, Seonah Kang, Anthony K. Park, Jianming Lu, Annie Yang, Zhifang Zhang, Isabella A. Bagdasarian, Yanghee Woo, Joshua T. Morgan, Zhirong Yin, Yuman Fong, Susanne G. Warner
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 864-872 (2022)
Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed. Vitamin D analogs such as calcipotriol (Ca
Externí odkaz:
https://doaj.org/article/b5d91ed5c6a549feb97cb488438d4bd7
Autor:
Zhifang Zhang, Annie Yang, Shyambabu Chaurasiya, Anthony K. Park, Sang-In Kim, Jianming Lu, Hannah Valencia, Yuman Fong, Yanghee Woo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14189 (2023)
We studied the immunotherapeutic potential of CF33-hNIS-antiPDL1 oncolytic virus (OV) against gastric cancer with peritoneal metastasis (GCPM). We collected fresh malignant ascites (MA) or peritoneal washings (PW) during routine paracenteses and diag
Externí odkaz:
https://doaj.org/article/ccb6c7ad833f489791c7f7f0f10ecad2
Autor:
Shyambabu Chaurasiya, Sang-In Kim, Michael O’Leary, Anthony K. Park, Jianming Lu, Seonah Kang, Zhifang Zhang, Annie Yang, Yanghee Woo, Yuman Fong, Susanne G. Warner
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 303-310 (2021)
Oncolytic viruses infect, replicate in, and kill cancer cells, leaving normal cells unharmed; they also recruit and activate immune cells against tumor cells. While clinical indications for viroimmunotherapy are growing, barriers to widespread treatm
Externí odkaz:
https://doaj.org/article/793296c2361d438a99b0c7793ab73a81
Autor:
Sang-In Kim, Mu-Yeong Lee, Hye Sook Jeon, Inhwan Cha, Hyoung Ook Park, Kil-Wook Yeo, Junghwa An
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 5, Iss 3, Pp 3516-3518 (2020)
The mitochondrial genome of Calidris tenuirostris and Limosa lapponica were described using the whole mitochondrial genome obtained from Illumina Next-Generation Sequencing (NGS) technology. Total length of the mitogenome of C. tenuirostris was 16,73
Externí odkaz:
https://doaj.org/article/f48e5bc75ffb4b2699824392de2d9cea
Autor:
Susanne G. Warner, Sang-In Kim, Shyambabu Chaurasiya, Michael P. O’Leary, Jianming Lu, Venkatesh Sivanandam, Yanghee Woo, Nanhai G. Chen, Yuman Fong
Publikováno v:
Molecular Therapy: Oncolytics, Vol 13, Iss , Pp 82-92 (2019)
Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and ra
Externí odkaz:
https://doaj.org/article/018669abd663467ca3491a2b8b319288
Autor:
Shyambabu Chaurasiya, Annie Yang, Seonah Kang, Jianming Lu, Sang-In Kim, Anthony K. Park, Venkatesh Sivanandam, Zhifang Zhang, Yanghee Woo, Susanne G. Warner, Yuman Fong
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat. Breast cancer is considered to be poorly immunogenic and hence is less responsive to immunotherapies. We tested whether the oncolytic poxvirus CF
Externí odkaz:
https://doaj.org/article/38e2448c170c427d9feae2804ba0faf1
Publikováno v:
Molecular Therapy: Oncolytics, Vol 9, Iss , Pp 22-29 (2018)
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high recurrence rate and poor prognosis. Here, we describe a novel, chimeric orthopoxvirus (CF33) that efficiently kills TNBC. Cytotoxicity was assayed in vitro in fo
Externí odkaz:
https://doaj.org/article/b8f6fd83018b407bb9757779aba568e1