Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sang-Hyuk Chung"'
Publikováno v:
Viruses, Vol 13, Iss 3, p 433 (2021)
Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic functions in several cancers. While it has been shown to interact with the human papillomavirus 16 (HPV16) E7 oncoprotein, the functional significance of PKM2 in
Externí odkaz:
https://doaj.org/article/ffe2209b0cf2484a813ea31387b934e7
Autor:
Patricio Gariglio, Aykut Üren, Paul F. Lambert, Sang-Hyuk Chung, Rubén G. Contreras, Catalina Flores-Maldonado, Richard Schlegel, Enoc M. Cortés-Malagón, Xuefeng Liu, Gülay Bulut, José Bonilla-Delgado
PDF file - 108K, HPV16-E6 enhances canonical Wnt/�-catenin signaling pathway in primary human keratinocytes. Wnt/�-catenin pathway activation was assessed using the TOPFLASH construct. Human foreskin keratinocytes were co-transfected with, E6, HP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b8dea69b895bd691056f52a27642d6
https://doi.org/10.1158/1541-7786.22517044.v1
https://doi.org/10.1158/1541-7786.22517044.v1
Autor:
Patricio Gariglio, Aykut Üren, Paul F. Lambert, Sang-Hyuk Chung, Rubén G. Contreras, Catalina Flores-Maldonado, Richard Schlegel, Enoc M. Cortés-Malagón, Xuefeng Liu, Gülay Bulut, José Bonilla-Delgado
PDF file - 103K, The E6 oncoprotein interacts with Dvl2 but not with Dvl1 or Dvl3. COS7 cells were transiently transfected with HPV-E6 and one of the Dvl cDNAs. HPV-E6 was tagged with AU1, and the Dvl genes included Flag tags. Cell lysates were prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47836f78d9d611215eb396d138cff2c5
https://doi.org/10.1158/1541-7786.22517041.v1
https://doi.org/10.1158/1541-7786.22517041.v1
IHC conditions and information for antibodies and chemicals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc9604981657d9a736606e7a9b2e92e
https://doi.org/10.1158/1541-7786.22527210
https://doi.org/10.1158/1541-7786.22527210
Autor:
Patricio Gariglio, Aykut Üren, Paul F. Lambert, Sang-Hyuk Chung, Rubén G. Contreras, Catalina Flores-Maldonado, Richard Schlegel, Enoc M. Cortés-Malagón, Xuefeng Liu, Gülay Bulut, José Bonilla-Delgado
PDF file - 109K, HPV16-E6 but not HPV16-E7 oncoprotein enhances canonical Wnt/�-catenin pathway in cultured cells. (A) COS7 cells were transiently transfected with the TCF/B-catenin dependent luciferase reporter construct (TOPFLASH) and Renilla tog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba188abe78de66caccc562d522812eef
https://doi.org/10.1158/1541-7786.22517047
https://doi.org/10.1158/1541-7786.22517047
Publikováno v:
The American Journal of Pathology
Cervical dysplastic lesions called cervical intraepithelial neoplasias (CINs) need be treated to prevent cervical cancer. Currently available surgical procedures are effective, but the development of noninvasive treatment is warranted. In human papil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c5d99d8611111217728a665fb952df
https://doi.org/10.1016/j.ajpath.2019.08.013
https://doi.org/10.1016/j.ajpath.2019.08.013
Publikováno v:
Essays Biochem
There has been little progress for several decades in modalities to treat cervical cancer. While the cervix is a hormone-sensitive tissue, physiologic roles of estrogen receptor α (ERα), progesterone receptor (PR), and their ligands in this tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d5d8680312088372563fd545e9f20b
https://europepmc.org/articles/PMC8935983/
https://europepmc.org/articles/PMC8935983/
Publikováno v:
Am J Pathol
While the uterine cervix responds to the female sex hormone change, the role of progesterone in cervical cancer is poorly understood. It has been shown that medroxyprogesterone acetate (MPA) regresses cervical cancer in the transgenic mouse model exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674728834f9f4e29398242980df670b9
https://pubmed.ncbi.nlm.nih.gov/34774516
https://pubmed.ncbi.nlm.nih.gov/34774516
Publikováno v:
Mol Cancer Res
Tumor-suppressor genes (TSG) are often deleted or transcriptionally suppressed in cancer. PGR codes for progesterone receptor (PR), a transcription factor whose function depends on its ligand. Although PR expression is often undetectable in cervical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b901bb777bb7b3bc48cc69db034ec3c2
https://europepmc.org/articles/PMC7785602/
https://europepmc.org/articles/PMC7785602/