Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sang Uk-Nham"'
Publikováno v:
Molecules and Cells
Complement fragment iC3b serves as a major opsonin for facilitating phagocytosis via its interaction with complement receptors CR3 and CR4, also known by their leukocyte integrin family names, αMβ2 and αXβ2, respectively. Although there is genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d53435e9bf4a61e47dcbbab9c5e6da9
https://pubmed.ncbi.nlm.nih.gov/33372665
https://pubmed.ncbi.nlm.nih.gov/33372665
Autor:
Sang-Uk Nham, Dolgorsuren Buyannemekh
Publikováno v:
Molecules and Cells
The β2 integrins are cell surface transmembrane proteins regulating leukocyte functions, such as adhesion and migration. Two members of β2 integrin, αMβ2 and αXβ2, share the leukocyte distribution profile and integrin αXβ2 is involved in anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8c8f4823ce61837e4a01b0da6f66dd
https://pubmed.ncbi.nlm.nih.gov/28535664
https://pubmed.ncbi.nlm.nih.gov/28535664
Publikováno v:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The {beta}2 integrins are found exclusively in leukocytes and they are composed of a common {beta} chain, CD18, and one of four unique {alpha} chains, CD11a ({alpha}L subunit), CD11b ({alpha}M subunit), CD11c ({alpha}X subunit), or CD11d ({alpha}D su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90e166d3893ea3bc34a6a1d588b8943
https://doi.org/10.1016/j.bbrc.2005.04.006
https://doi.org/10.1016/j.bbrc.2005.04.006
Autor:
Milan S. Blake, Sang Uk-Nham, J G Cannon, Eric J. Brown, Michael A. Apicella, Jennifer L. Edwards
Publikováno v:
Cellular Microbiology. 4:571-584
Little is known about the pathogenesis of gonococcal infection within the lower female genital tract. We recently described the distribution of complement receptor 3 (CR3) on epithelia of the female genital tract. Our studies further indicate that CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9bb434428561324195016e4c7258f1
https://doi.org/10.1046/j.1462-5822.2002.t01-1-00215.x
https://doi.org/10.1046/j.1462-5822.2002.t01-1-00215.x
Autor:
Sang-Uk Nham, Jeungsook Choi
Publikováno v:
Biochemical and Biophysical Research Communications. 292:756-760
The I domains of CD11 are responsible for the binding of ligands and have a unique structure with 6-7 alpha helices and 6 beta sheets with interconnecting loops. To determine loops recognizing fibrinogen in CD11c I domain, five oligopeptides correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85cab2dadfcba6606b1e04626d876c0
https://doi.org/10.1006/bbrc.2002.6705
https://doi.org/10.1006/bbrc.2002.6705
Publikováno v:
Biotechnology Letters. 16:661-666
A full-length aFGF cDNA was cloned and inserted into a T7 expression vector for heterologous expression inE. coli. For high level production of aFGF, an optimal condition for overexpression (incubation at 42 °C for 2 hours) and a simple purification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c42124d6ba41e954aff7fd70400c5e4
https://doi.org/10.1007/bf00136467
https://doi.org/10.1007/bf00136467
Publikováno v:
Molecules and cells. 30(3)
Integrin αXβ2 performs a significant role in leukocyte functions including phagocytosis and migration, and binds to a variety of ligands, including fibrinogen, iC3b, and ICAM-1. A particular domain of the α subunit of the integrin - the αX I-doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00398a222a410baa57e67732fb108d1c
https://pubmed.ncbi.nlm.nih.gov/20803088
https://pubmed.ncbi.nlm.nih.gov/20803088
Autor:
Andrew F. G. Quest, Lisette Leyton, Sang Uk Nham, Nicolás Muñoz, Alejandra Valdivia, Tamara Hermosilla, Daniel Muñoz, Rodrigo Herrera-Molina, Keith Burridge, Pascal Schneider
Publikováno v:
Biochim Biophys Acta
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH
Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1783, no. 6, pp. 1111-1120
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH
Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1783, no. 6, pp. 1111-1120
Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a beta3-containing integrin in astrocytes to induce tyrosine phosphorylation, RhoA activation and the formation of foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6392f2986333ab27935615918a2c14a
Publikováno v:
Genomics. 8:710-716
The MUT locus encoding the enzyme methylmalonyl-CoA mutase is defective in mut forms of methylmalonic acidemia. This locus has been mapped to chromosome 6p12-21.1. We report cloning and characterization of this locus which comprises 13 exons spanning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1348c2db1ee221a8de5e741c361f2be
https://doi.org/10.1016/0888-7543(90)90259-w
https://doi.org/10.1016/0888-7543(90)90259-w
Publikováno v:
Molecules and cells. 24(2)
The beta2 integrins on leukocytes play important roles in cell adhesion, migration and phagocytosis. One of the beta2 integrins, alphaXbeta2 (CD11c/CD18), is known to bind ligands such as fibrinogen, Thy-1 and iC3b, but its function is not well chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30c34134a1b44f3ee5e828e2daab6882
https://pubmed.ncbi.nlm.nih.gov/17978577
https://pubmed.ncbi.nlm.nih.gov/17978577