Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sang Su Oh"'
Autor:
Colin K. Franz, Thais Federici, Jun Yang, Carey Backus, Sang Su Oh, Qingshan Teng, Erin Carlton, Kathie M. Bishop, Mehdi Gasmi, Raymond T. Bartus, Eva L. Feldman, Nicholas M. Boulis
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 3, Pp 473-481 (2009)
Background: Amyotrophic lateral sclerosis (ALS) is a devastating disease that is characterized by the progressive loss of motor neurons. Patients with ALS usually die from respiratory failure due to respiratory muscle paralysis. Consequently, therapi
Externí odkaz:
https://doaj.org/article/b08a536399554ec89b5daddd1dab6e3b
Autor:
Kelli A. Sullivan, John M. Hayes, Timothy D. Wiggin, Carey Backus, Sang Su Oh, Stephen I. Lentz, Frank Brosius, III, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 276-285 (2007)
Diabetic neuropathy (DN) is a debilitating complication of type 1 and type 2 diabetes. Rodent models of DN do not fully replicate the pathology observed in human patients. We examined DN in streptozotocin (STZ)-induced [B6] and spontaneous type 1 dia
Externí odkaz:
https://doaj.org/article/e226b4e0acac404d9de97b13a82cc4b6
Publikováno v:
Anticancer research. 42(9)
Patients with breast cancer frequently encounter a dismal prognosis due to the lack of effective and curative therapies. MicroRNAs (miRNAs) are aberrantly regulated in many types of cancer and have been recognized to play crucial roles in cancer prog
Autor:
Audrey B. Erman, Osama N. Kashlan, Kevin S. Chen, Stacey A. Sakowski, Robbi A. Kupfer, Lisa M. McGinley, Sang Su Oh, Eva L. Feldman, Bader N. Kashlan
Publikováno v:
Neurodegenerative Diseases. 15:121-126
Background: Almost all patients with amyotrophic lateral sclerosis (ALS) develop bulbar symptoms; therefore, it is important to have valid animal models that accurately reflect these features. While the SOD1-G93A rat is extensively used as an ALS mod
Publikováno v:
The Laryngoscope. 123:2216-2227
Objectives/Hypothesis To enhance understanding of spontaneous laryngeal muscle reinnervation following severe recurrent laryngeal nerve injury by testing the hypotheses that 1) nerve fibers responsible for thyroarytenoid muscle reinnervation can orig
Autor:
Carey Backus, John M. Hayes, Eva L. Feldman, Sang Su Oh, Kelli A. Sullivan, Stacey A. Sakowski, John E. Wilkinson
Publikováno v:
Neuroscience. 212:201-213
The contribution of oxidative stress to diabetic complications including neuropathy is widely known. Mitochondrial and cellular damage are associated with the overproduction of reactive oxygen species and decreased levels or function of the cellular
Publikováno v:
International Journal of Diabetes and Metabolism. 20:59-63
Our laboratory recently identified several differentially expressed genes (DEG) through microarray analysis of the sciatic nerves of 24-week-old BKS db/db (diabetic) and db/+ (nondiabetic) mice. We noted prominent increases in lipid metabolism genes,
Autor:
Junguk Hur, Manjusha Pande, Sang Su Oh, Eva L. Feldman, Carey Backus, John M. Hayes, Yu Hong, Matthias Kretzler
Publikováno v:
Diabetes
OBJECTIVE A better understanding of the molecular mechanisms underlying the development and progression of diabetic neuropathy (DN) is essential for the design of mechanism-based therapies. We examined changes in global gene expression to define path
Autor:
Cynthia M. van Golen, Kenneth L. van Golen, Mary E. Soules, Bhumsoo Kim, Eva L. Feldman, Kevin Fung, Sang Su Oh, Tracy S. Schwab
Publikováno v:
Cancer Research. 66:6570-6578
Neuroblastoma is a pediatric tumor that preferentially metastasizes to bone. Patients with bone metastases have a mortality rate >93%, indicating a need for novel treatment targets. Our laboratory has shown that type I insulin-like growth factor rece
Publikováno v:
Cellular Signalling. 17:769-775
Insulin receptor substrate (IRS) proteins are major docking molecules for the type I insulin like growth factor (IGF) receptor (IGF-IR) and mediate their effects on downstream signaling molecules. In this report, we investigated IRS-1 regulation duri