Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Sang Myun, Park"'
Autor:
Sushil Gaire, Jiawei An, Haijie Yang, Keon Ah Lee, Manisha Dumre, Eun Jeong Lee, Sang-Myun Park, Eun-Hye Joe
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract In this study, we examined how systemic inflammation affects repair of brain injury. To this end, we created a brain-injury model by stereotaxic injection of ATP, a damage-associated molecular pattern component, into the striatum of mice. Sy
Externí odkaz:
https://doaj.org/article/b022e10cf75b48c4a7e3e0eac1a94a9f
Publikováno v:
Neurobiology of Disease, Vol 197, Iss , Pp 106528- (2024)
Background: Brain injury has been suggested as a risk factor for neurodegenerative diseases. Accordingly, defects in the brain's intrinsic capacity to repair injury may result in the accumulation of damage and a progressive loss of brain function. Th
Externí odkaz:
https://doaj.org/article/cda3153376504798821f65380e1c04d2
Autor:
Jae-Bong Kim, Yujeong Kim, Soo-Jeong Kim, Tae‑Young Ha, Dong-Kyu Kim, Dong Won Kim, Minyoung So, Seung Ho Kim, Hyun Goo Woo, Dukyong Yoon, Sang Myun Park
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Parkinson’s disease (PD) is a common and costly progressive neurodegenerative disease of unclear etiology. A disease-modifying approach that can directly stop or slow its progression remains a major unmet need in the treatment o
Externí odkaz:
https://doaj.org/article/70e5dd38eedb47e197a1c6a99b744274
Publikováno v:
Cells, Vol 13, Iss 22, p 1876 (2024)
Glucose metabolism is essential for the maintenance and function of the central nervous system. Although the brain constitutes only 2% of the body weight, it consumes approximately 20% of the body’s total energy, predominantly derived from glucose.
Externí odkaz:
https://doaj.org/article/cf31c7321e254b9188e50820a138622e
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Gut dysbiosis and psychiatric symptoms are common early manifestations of Alzheimer’s disease (AD) and Parkinson’s disease (PD). These diseases, characterised by progressive neuron loss and pathological protein accumulation, impose debilitating e
Externí odkaz:
https://doaj.org/article/8ae39a79b6254e47982aab38bc1d20dd
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, with aging being considered the greatest risk factor for developing PD. Caveolin-1 (Cav-1) is known to participate in the aging process. Recent evidence indicat
Externí odkaz:
https://doaj.org/article/b591a9a6efb2444e8be6798509cf3bb5
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract In addition to providing structural support, caveolin-1 (Cav1), a component of lipid rafts, including caveolae, in the plasma membrane, is involved in various cellular mechanisms, including signal transduction. Although pre-synaptic membrane
Externí odkaz:
https://doaj.org/article/51cf6c01b3ea4c1f8c745d5f9c4def4e
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated mo
Externí odkaz:
https://doaj.org/article/4b300607bebb46c29c01e5761d54b25b
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. PD is pathologically characterized by the death of midbrain dopaminergic neurons and the accumulation of intracellular protein inclusions called Lewy bodies or Lewy neur
Externí odkaz:
https://doaj.org/article/89929b26250b4fae8f0363cb6b968b8a
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 482-491 (2019)
Dysfunctional regulation of inflammation may contribute to the progression of neurodegenerative diseases. The results of this study revealed that DJ-1, a Parkinson's disease (PD) gene, regulated expression of prostaglandin D2 synthase (PTGDS) and pro
Externí odkaz:
https://doaj.org/article/86d0de2bc78c4ab882a30a171a661813