Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Sang Mi Shin"'
Autor:
Jitendra Shrestha, Sung Hwan Ki, Sang Mi Shin, Seon Woong Kim, Joo-Youn Lee, Hee-Sook Jun, Taeho Lee, Sanghee Kim, Dong Jae Baek, Eun-Young Park
Publikováno v:
Molecules, Vol 23, Iss 11, p 2750 (2018)
FTY720 inhibits various cancers through PP2A activation. The structure of FTY720 is also used as a basic structure for the design of sphingosine kinase (SK) inhibitors. We have synthesized derivatives using an amide chain in FTY720 with a phenyl back
Externí odkaz:
https://doaj.org/article/7cb8117eae5445d888926005adce84f7
Publikováno v:
PPAR Research, Vol 2008 (2008)
Peroxisome proliferator-activated receptor-γ (PPARγ) and retinoic acid X-receptor (RXR) heterodimer, which regulates cell growth and differentiation, represses the TGFβ1 gene that encodes for the protein involved in cancer biology. This review wil
Externí odkaz:
https://doaj.org/article/198458757d3942c0b199f209abe1d7df
Autor:
Sang Mi Shin, Hyunjung Kim
Publikováno v:
Dance Research Journal of Dance. 79:29-47
Autor:
Jin Beom Kim, Il Je Cho, Ji Hye Yang, Eun Young Park, Sung Hwan Ki, Seung Sik Cho, Kyu Hwa Seo, Deuk Sil Oh, Geon Ung Jo, Eo Ji Hyun, Chun-Soo Na, Jong Seok Park, Sang Mi Shin, Sae-Kwang Ku, Sam Seok Cho
Publikováno v:
Journal of Medicinal Food. 22:602-613
The fruits, leaves, and roots of Cudrania tricuspidata have been reported to contain large amounts of vitamin B, vitamin C, and flavonoids. They exhibit various physiological activities su...
Autor:
Sanghee Kim, Tae-Ho Lee, Seon Woong Kim, Eun Young Park, Sang Mi Shin, Yoon Sin Oh, Dong Jae Baek, Joo-Youn Lee
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:599-603
The PF-543 is known as a potent and selective inhibitor of sphingosine kinase (SK) 1 amongst all the SK inhibitors known to date. In a recently reported study by Pfizer on the synthesis of PF-543 derivatives and the SK inhibitory effects, the introdu
Autor:
Jitendra Shrestha, Sang Mi Shin, Eun Young Park, Tae-Ho Lee, Doohyun Lee, Yoon Sin Oh, Dong Jae Baek
Publikováno v:
Bulletin of the Korean Chemical Society. 39:261-264
Autor:
Sang Mi Shin, Kyuhwa Seo
Publikováno v:
Toxicological Research
Lipin1 was identified as a phosphatidate phosphatase enzyme, and it plays a key role in lipid metabolism. Since free radicals contribute to metabolic diseases in the liver, this study investigated the effects of free radicals on the regulation of Lip
Publikováno v:
Archives of Pharmacal Research. 40:231-239
5-Fluorouracil (5-FU) is a chemotherapeutic agent used in the treatment of colorectal cancer. In this study, we investigated whether 5-FU induces Sestrin2 (SESN2), an antioxidant enzyme, and the role of SESN2 in 5-FU action in colon cancer cells. We
Publikováno v:
Free Radical Biology and Medicine. 101:511-523
Sestrin2 (SESN2) is an antioxidant protein that modulates cellular redox homeostasis through regeneration of peroxiredoxins. It has beneficial effects in oxidative or metabolic stress conditions as an upstream regulator of AMP-activated protein kinas
Autor:
Kyu Min Kim, Ji Hye Yang, Sang Mi Shin, Sun O Ka, Hee-Jeong Lee, Byung Hyun Park, Chang-Su Na, Il Je Cho, Jae Kwang Kim, Sung Hwan Ki, Kyung Hwan Jegal, Sang-Gon Park, Sam Seok Cho, Sae-Kwang Ku
Publikováno v:
Antioxidantsredox signaling. 31(3)
Aims: Hepatic fibrosis results from chronic liver injury and inflammatory responses. Sestrin 2 (Sesn2), an evolutionarily conserved antioxidant enzyme, reduces the severities of acute hepa...