Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Sang Jun Han"'
Publikováno v:
Kidney Research and Clinical Practice, Vol 43, Iss 3, Pp 313-325 (2024)
Background The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and a blockage of the shortening disturbs the ability
Externí odkaz:
https://doaj.org/article/ae637f382c874171ba9a177b288547da
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Steroid receptor coactivators (SRCs) are master regulators of transcription that play key roles in human physiology and pathology. SRCs are particularly important for the regulation of the immune system with major roles in lymphocyte fate determinati
Externí odkaz:
https://doaj.org/article/d1f0e255f7694eb5bb1823eabdc18893
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8145 (2024)
In patients with endometriosis, refluxed endometrial fragments evade host immunosurveillance, developing into endometriotic lesions. However, the mechanisms underlying this evasion have not been fully elucidated. N-Myc and STAT Interactor (NMI) have
Externí odkaz:
https://doaj.org/article/4dfff777ae924c95b9f791060bc491e5
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 3, Pp 325-339 (2023)
Background Renal fibrosis is characterized by the accumulation of extracellular matrix and inflammatory cells and kidney dysfunction, which is a major pathway in the progression of chronic kidney disease (CKD). Accumulating evidence indicates that ox
Externí odkaz:
https://doaj.org/article/9dd15dbebb55491e8239e43e65ec9195
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 3, Pp 312-324 (2023)
Background The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions. In kidneys, the primary cilia protrude into
Externí odkaz:
https://doaj.org/article/f9a58959fef543a2b0a76b3424c9898b
Diminazene aceturate exacerbates renal fibrosis after unilateral ureteral obstruction in female mice
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 2, Pp 188-201 (2023)
Background Diminazene aceturate (DIZE), an angiotensin-converting enzyme 2 (ACE2) activator, exerts anti-inflammatory and antifibrotic effects in a variety of human chronic diseases. However, the role of DIZE in kidney fibrosis and the underlying mec
Externí odkaz:
https://doaj.org/article/98bc448f4c3c4ccebab3dcd0a584d4f6
Autor:
Yuri Park, Yeon Jean Cho, Nuri Sung, Mi Jin Park, Xiaoming Guan, William E. Gibbons, Bert W. O’Malley, Sang Jun Han
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Endometriosis is an estrogen-dependent inflammatory reproductive disease. Therefore, systematic estrogen depletion and anti-inflammatory drugs are the current treatment for endometriosis. However, current endometriosis treatments
Externí odkaz:
https://doaj.org/article/3f0ffb4872d84f4ba91d221f22a56ae7
Autor:
Hyun Young Kwon, Seung Bin Park, Myoungseok Han, Jung-Woo Park, Yongmin Lee, Sang jun Han, Youngmin Kwon, Yeon Jean Cho
Publikováno v:
Obstetrics & Gynecology Science, Vol 65, Iss 6, Pp 531-541 (2022)
Objective Triphenyl phosphate (TPHP) is one of the most commonly used organophosphorus flame retardants that may accumulate in the environment. However, its effects on human reproductive organs have not been well studied. We aimed to investigate the
Externí odkaz:
https://doaj.org/article/ebb2d9730a344b908f261b21fe304984
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-23 (2022)
Abstract Background The tumor immune microenvironment (TIME) generated by cancer-infiltrating immune cells has a crucial role in promoting or suppressing breast cancer progression. However, whether the steroid receptor coactivator-3 (SRC-3) modulates
Externí odkaz:
https://doaj.org/article/19f064f8057e44cd82a7004520240405
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hepatic ischemia/reperfusion (I/R) injury is one of the leading causes of mortality following partial hepatectomy, liver transplantation, hypovolemic shock and trauma; however, effective therapeutic targets for the treatment of hepatic I/R i
Externí odkaz:
https://doaj.org/article/7c3adf50972c40cf8c725852d4c9c6b5