Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Sang Hyun Song"'
Autor:
Sang Hyun Song, Dawool Han, Kyeonghui Park, Jo Eun Um, Seonghun Kim, Minhee Ku, Jaemoon Yang, Tae-Hyun Yoo, Jong In Yook, Nam Hee Kim, Hyun Sil Kim
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundApproximately 30% of diabetic patients develop diabetic nephropathy, a representative microvascular complication. Although the etiological mechanism has not yet been fully elucidated, renal tubular damage by hyperglycemia-induced expression
Externí odkaz:
https://doaj.org/article/fa6086bf22c54af1bae137fd9acc7bdf
Autor:
Seonghun Kim, Cheol-Hee Jeong, Sang Hyun Song, Jo Eun Um, Hyun Sil Kim, Jun Seop Yun, Dawool Han, Eunae Sandra Cho, Bo Young Nam, Jong In Yook, Minhee Ku, Jaemoon Yang, Man-Deuk Kim, Nam Hee Kim, Tae-Hyun Yoo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Tubulointerstitial renal fibrosis is a chronic disease process affecting chronic kidney disease (CKD). While the etiological role of transforming growth factor-beta (TGF-β) is well known for epithelial–mesenchymal transition (EMT) in chronic kidne
Externí odkaz:
https://doaj.org/article/291e68acb87e446ab909fda7a1ff3097
Autor:
Nam Hee Kim, Sang Hyun Song, Yun Hee Choi, Kyu Ho Hwang, Jun Seop Yun, Hyeeun Song, So Young Cha, Sue Bean Cho, Inhan Lee, Hyun Sil Kim, Jong In Yook
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9589 (2021)
The epithelial-mesenchymal transition (EMT) comprises an important biological mechanism not only for cancer progression but also in the therapeutic resistance of cancer cells. While the importance of the protein abundance of EMT-inducers, such as Sna
Externí odkaz:
https://doaj.org/article/62f1c1ab2f754a8c91625060cce30d17
Autor:
Hee Eun Kang, Yoojeong Seo, Jun Seop Yun, Sang Hyun Song, Dawool Han, Eunae Sandra Cho, Sue Bean Cho, Yoon Jeon, Ho Lee, Hyun Sil Kim, Joyeon Kang, Jong In Yook, Nam Hee Kim, Tae Il Kim
Publikováno v:
Cancers, Vol 13, Iss 14, p 3437 (2021)
The Wnt and Hippo pathways are tightly coordinated and understanding their reciprocal regulation may provide a novel therapeutic strategy for cancer. Anti-helminthic niclosamide is an effective inhibitor of Wnt and is now in a phase II trial for adva
Externí odkaz:
https://doaj.org/article/7ef8c6f285d44153adae3b6cdba0d15b
Autor:
Young‐Won Cho, Dong‐Wook Min, Hwang‐Phill Kim, Yohan An, Sheehyun Kim, Jeonghwan Youk, Jaeyoung Chun, Jong Pil Im, Sang‐Hyun Song, Young Seok Ju, Sae‐Won Han, Kyu Joo Park, Tae‐You Kim
Publikováno v:
Molecular Oncology, Vol 16, Iss 12, Pp 2396-2412 (2022)
Patient‐derived organoids are being considered as models that can help guide personalized therapy through in vitro anticancer drug response evaluation. However, attempts to quantify in vitro drug responses in organoids and compare them with respons
Externí odkaz:
https://doaj.org/article/11f7fe63d5334fa3933c273c28144f06
Autor:
Seul‐Ki Cheon, Hwang‐Phill Kim, Ye‐Lim Park, Jee‐Eun Jang, Yoojoo Lim, Sang‐Hyun Song, Sae‐Won Han, Tae‐You Kim
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1398-1409 (2018)
Although MEK blockade has been highlighted as a promising antitumor drug, it has poor clinical efficacy in KRAS mutant colorectal cancer (CRC). Several feedback systems have been described in which inhibition of one intracellular pathway leads to act
Externí odkaz:
https://doaj.org/article/3c8611d9db3043a3b211f6b01875be0f
Autor:
Jun Seop Yun, Hyeeun Song, Nam Hee Kim, So Young Cha, Kyu Ho Hwang, Jae Eun Lee, Cheol-Hee Jeong, Sang Hyun Song, Seonghun Kim, Eunae Sandra Cho, Hyun Sil Kim, Jong In Yook
Publikováno v:
Molecules and Cells. 45:911-922
A structural protein of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), nucleocapsid (N) protein is phosphorylated by glycogen synthase kinase (GSK)-3 on the serine/arginine (SR) rich motif located in disordered regions. Although phosph
Publikováno v:
Molecular Oncology, Vol 12, Iss 7, Pp 993-1003 (2018)
Although regorafenib has demonstrated survival benefits in patients with metastatic colorectal and gastrointestinal stromal tumors, no proven biomarker has been identified for predicting sensitivity to regorafenib. Here, we investigated preclinical a
Externí odkaz:
https://doaj.org/article/be9cc0c3a27a4dd0bc7ca6a74ef39957
Autor:
Sang-Hyun Song, Tae-You Kim
Publikováno v:
Genomics & Informatics, Vol 15, Iss 4, Pp 114-122 (2017)
It is becoming increasingly clear that eukaryotic genomes are subjected to higher-order chromatin organization by the CCCTC-binding factor/cohesin complex. Their dynamic interactions in three dimensions within the nucleus regulate gene transcription
Externí odkaz:
https://doaj.org/article/eb9d2925bc1f458996df99cba53dacc8
Publikováno v:
Nano Convergence, Vol 4, Iss 1, Pp 1-6 (2017)
Abstract In this study, ITO nanoparticles (ITO-NPs) were reused from ITO target scraps to synthesize low cost ITO-NPs and to apply to make sputtering target for transparent conductive electrodes (TCEs). By controlling heat-treatment temperature as 98
Externí odkaz:
https://doaj.org/article/a961139e3de3439eafc1efe1197ad8e8