Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sang Hyeon Hann"'
Autor:
Joonwoo Rhee, Jong‐Seol Kang, Young‐Woo Jo, Kyusang Yoo, Ye Lynne Kim, Sang‐Hyeon Hann, Yea‐Eun Kim, Hyun Kim, Ji‐Hoon Kim, Young‐Yun Kong
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 4, Pp 1404-1417 (2024)
Abstract Background Zolgensma is a gene‐replacement therapy that has led to a promising treatment for spinal muscular atrophy (SMA). However, clinical trials of Zolgensma have raised two major concerns: insufficient therapeutic effects and adverse
Externí odkaz:
https://doaj.org/article/a56693d68b7f4f60bf7ae75f4aeebea6
Autor:
Kyusang Yoo, Young-Woo Jo, Takwon Yoo, Sang-Hyeon Hann, Inkuk Park, Yea-Eun Kim, Ye Lynne Kim, Joonwoo Rhee, In-Wook Song, Ji-Hoon Kim, Daehyun Baek, Young-Yun Kong
Publikováno v:
eLife, Vol 13 (2024)
Fibro-adipogenic progenitors (FAPs) are muscle-resident mesenchymal progenitors that can contribute to muscle tissue homeostasis and regeneration, as well as postnatal maturation and lifelong maintenance of the neuromuscular system. Recently, traumat
Externí odkaz:
https://doaj.org/article/9b7e68a933bb41308da06d05c41c3bad
Autor:
Sang-Hyeon Hann, Seon-Yong Kim, Ye Lynne Kim, Young-Woo Jo, Jong-Seol Kang, Hyerim Park, Se-Young Choi, Young-Yun Kong
Publikováno v:
eLife, Vol 12 (2024)
Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by the deficiency of the survival motor neuron (SMN) protein, which leads to motor neuron dysfunction and muscle atrophy. In addition to the requirement for SMN in motor neurons,
Externí odkaz:
https://doaj.org/article/8f406834006c452fbdaf5d6029f9d156
Autor:
Ji‐Hoon Kim, Inkuk Park, Hijai R. Shin, Joonwoo Rhee, Ji‐Yun Seo, Young‐Woo Jo, Kyusang Yoo, Sang‐Hyeon Hann, Jong‐Seol Kang, Jieon Park, Ye Lynne Kim, Ju‐Yeon Moon, Man Ho Choi, Young‐Yun Kong
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 177-191 (2021)
Abstract Background With organismal aging, the hypothalamic–pituitary–gonadal (HPG) activity gradually decreases, resulting in the systemic functional declines of the target tissues including skeletal muscles. Although the HPG axis plays an impor
Externí odkaz:
https://doaj.org/article/5c55131d0f054ccebc3bb718e07003a2
Autor:
Ji-Yun Seo, Jong-Seol Kang, Ye Lynne Kim, Young-Woo Jo, Ji-Hoon Kim, Sang-Hyeon Hann, Jieon Park, Inkuk Park, Hyerim Park, Kyusang Yoo, Joonwoo Rhee, Jung-Wee Park, Yong Chan Ha, Young-Yun Kong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Muscle atrophy is associated with ageing, but the underlying molecular mechanisms are not well understood. Here, they authors show that ablation of the E3 ubiquitin ligase Mib1 is important for myofibre maintenance via a mechanism that involves targe
Externí odkaz:
https://doaj.org/article/186250f8decc4f9ea8ae3d425ceeb8b9
Autor:
Ji-Hoon Kim, Jong-Seol Kang, Kyusang Yoo, Jinguk Jeong, Inkuk Park, Jong Ho Park, Joonwoo Rhee, Shin Jeon, Young-Woo Jo, Sang-Hyeon Hann, Minji Seo, Seungtae Moon, Soo-Jong Um, Rho Hyun Seong, Young-Yun Kong
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
The survival of motor neuron (SMN) protein is a major component of the pre-mRNA splicing machinery and is required for RNA metabolism. Although SMN has been considered a fundamental gene for the central nervous system, due to its relationship with ne
Externí odkaz:
https://doaj.org/article/a3c7d5a5a347457788381a2e9bf92ff5
Autor:
Kyusang Yoo, Jieon Park, Young-Woo Jo, Hijai R. Shin, Ju-Yeon Moon, Ji Hoon Kim, Ye Lynne Kim, Young-Yun Kong, Jong-Seol Kang, Man Ho Choi, Ji-Yun Seo, Inkuk Park, Sang-Hyeon Hann, Joonwoo Rhee
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 177-191 (2021)
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 177-191 (2021)
Background With organismal aging, the hypothalamic–pituitary–gonadal (HPG) activity gradually decreases, resulting in the systemic functional declines of the target tissues including skeletal muscles. Although the HPG axis plays an important role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bbf6a5eb8df82f6469bec1956b3810
http://europepmc.org/articles/PMC7890269
http://europepmc.org/articles/PMC7890269
Autor:
Jieon Park, Kyusang Yoo, Joonwoo Rhee, Jung-Wee Park, Jong-Seol Kang, Young-Yun Kong, Yong-Chan Ha, Hyerim Park, Inkuk Park, Ye Lynne Kim, Ji-Yun Seo, Young-Woo Jo, Ji Hoon Kim, Sang-Hyeon Hann
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Age-associated muscle atrophy is a debilitating condition associated with loss of muscle mass and function with age that contributes to limitation of mobility and locomotion. However, the underlying mechanisms of how intrinsic muscle changes with age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5c30b83806c8eb0c9af795b1da947f
https://pubmed.ncbi.nlm.nih.gov/33637766
https://pubmed.ncbi.nlm.nih.gov/33637766
Autor:
Daekwan Seo, Su Hyeon Lee, Sang-Hyeon Hann, Jinwoo Seong, Ji-Yun Seo, Wookjin Park, Ji Hoon Kim, Young-Guen Kwon, Hyun-Woo Jeong, Min-Kyu Yum, Sung-hwan Bae, Inkuk Park, Gi-Chan Han, Young-Yun Kong, Man Ho Choi
Publikováno v:
Nature cell biology. 18(10)
Nature Cell Biology 18, 930–940 (2016); published online 22 August 2016; corrected after print 8 September 2016 In the version of this Article originally published, in the key in Fig. 1b, the red and black data points were incorrectly labelled; the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709bbbc1cb45cd3cbabef1180ff81c33
https://pubmed.ncbi.nlm.nih.gov/27548913
https://pubmed.ncbi.nlm.nih.gov/27548913
Autor:
Min Kyu Yum, Ji Hoon Kim, Sang Hyeon Hann, Su Hyeon Lee, Daekwan Seo, Inkuk Park, Young-Yun Kong, Wookjin Park, Sung Hwan Bae, Ji Yun Seo, Jinwoo Seong, Hyun-Woo Jeong, Gi Chan Han, Man Ho Choi, Young Guen Kwon
Publikováno v:
Nature cell biology. 18(9)
Quiescent satellite cells, known as adult muscle stem cells, possess a remarkable ability to regenerate skeletal muscle following injury throughout life. Although they mainly originate from multipotent stem/progenitor cells of the somite, the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08f6f337710d526ff39bcf3aac29194
https://pubmed.ncbi.nlm.nih.gov/27684507
https://pubmed.ncbi.nlm.nih.gov/27684507