Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Sang Hyeok Woo"'
Autor:
Hui-Ching Chuang, Liang Peng Yang, Alison L Fitzgerald, Abdullah Osman, Sang Hyeok Woo, Jeffrey N Myers, Heath D Skinner
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104821 (2014)
TP53 is the most commonly mutated gene in head and neck cancer (HNSCC), with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 a
Externí odkaz:
https://doaj.org/article/2005e656d7ea487abb8a0a395bb10c9d
Autor:
Seok-Il Hong, In-Chul Park, Chang-Hun Rhee, Myung-Jin Park, Young-Joon Hong, Su-Jae Lee, Doo-Hyun Yoo, Tae-Boo Choe, Sung-Keum Seo, Hyeon-Ok Jin, Sang-Hyeok Woo, Hansoo Lee, Sungkwan An, Hyung-Chahn Lee
Supplementary Data from Activation of Epidermal Growth Factor Receptor and Its Downstream Signaling Pathway by Nitric Oxide in Response to Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510f40069aa0e55300e1975cdfef897c
https://doi.org/10.1158/1541-7786.22516807
https://doi.org/10.1158/1541-7786.22516807
Autor:
Seok-Il Hong, In-Chul Park, Chang-Hun Rhee, Myung-Jin Park, Young-Joon Hong, Su-Jae Lee, Doo-Hyun Yoo, Tae-Boo Choe, Sung-Keum Seo, Hyeon-Ok Jin, Sang-Hyeok Woo, Hansoo Lee, Sungkwan An, Hyung-Chahn Lee
Epidermal growth factor receptor (EGFR) is activated by ionizing radiation (IR), but the molecular mechanism for this effect is unknown. We have found that intracellular generation of nitric oxide (NO) by NO synthase (NOS) is required for the rapid a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc8ad12cdb33d7c5ac051fe2bb54c086
https://doi.org/10.1158/1541-7786.c.6541492
https://doi.org/10.1158/1541-7786.c.6541492
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Assessment of the degree of synergy between cisplatin and MK-1775 in HN30 (wild-type TP53) and HN31 (mutant TP53) HNSCC cells respectively using the Chou and Talalay method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6352838fedef24046c6d1458ef5d2e
https://doi.org/10.1158/1535-7163.22503727.v1
https://doi.org/10.1158/1535-7163.22503727.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Determination of drug synergy by the combination-index and isobologram analyses using the CalcuSyn software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b6583d3f2e7dbca8d53f20c5eca8
https://doi.org/10.1158/1535-7163.22503718.v1
https://doi.org/10.1158/1535-7163.22503718.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
The Wee-1 inhibitor, MK-1775 Synergizes with cisplatin in vitro in established HNSCC cell lines with known TP53 mutational status; Dual phospho-H3 staining and PI flow cytometric analysis (FACS); The synergy between cisplatin and MK-1775 in HNSCC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872ee87af6f3bd14707abe7cf9ba62ff
https://doi.org/10.1158/1535-7163.22503730
https://doi.org/10.1158/1535-7163.22503730
Autor:
John V. Heymach, Jeffrey N. Myers, Raymond E. Meyn, Beth M. Beadle, David P. Molkentine, You Hong Fan, Li Shen, Lixia Diao, Jing Wang, Adel El-Naggar, Michelle D. Williams, Lauren A. Byers, Curtis R. Pickering, Michael D. Story, Sang Hyeok Woo, Liang Yang, Uma Giri, Heath D. Skinner
Purpose: Head and neck squamous cell carcinoma (HNSCC) is commonly treated with radiotherapy, and local failure after treatment remains the major cause of disease-related mortality. To date, human papillomavirus (HPV) is the only known clinically val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4dfde9c353c17ec301aab77dd24c01
https://doi.org/10.1158/1078-0432.c.6525296.v1
https://doi.org/10.1158/1078-0432.c.6525296.v1
Autor:
John V. Heymach, Jeffrey N. Myers, Raymond E. Meyn, Beth M. Beadle, David P. Molkentine, You Hong Fan, Li Shen, Lixia Diao, Jing Wang, Adel El-Naggar, Michelle D. Williams, Lauren A. Byers, Curtis R. Pickering, Michael D. Story, Sang Hyeok Woo, Liang Yang, Uma Giri, Heath D. Skinner
Supplemental methods Supplementary Figure 1. Total and phospho-PTK2/FAK is overexpressed in selected radioresistant HNSCC cells compared to radiosensitive cell lines via immunoblot. Supplementary Figure 2. A.) Inhibition of PTK2/FAK expression via st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dad3dbd0c6ae9bc5c5a767c55ec0f0
https://doi.org/10.1158/1078-0432.22463063.v1
https://doi.org/10.1158/1078-0432.22463063.v1
Autor:
YOONHWA PARK1,2, SANG HYEOK WOO1,3, SUNG-KEUM SEO1, HYUNGGEE KIM2, WOO CHUL NOH4, JIN KYUNG LEE3, BYOUNG-MOG KWON5, KYUNG NAM MIN6, TAE-BOO CHOE6 tbchoe@konkuk.ac.kr, IN-CHUL PARK1 parkic@kcch.re.kr
Publikováno v:
Oncology Letters. Oct2017, Vol. 14 Issue 4, p5027-5033. 7p.
Autor:
Jin Kyung Lee, Byoung Mog Kwon, Sang Hyeok Woo, Woo Chul Noh, Sung Keum Seo, Kyung Nam Min, Hyunggee Kim, Yoonhwa Park, In Chul Park, Tae Boo Choe
Publikováno v:
Oncology Letters. 14:5027-5033
Ginkgetin is a natural biflavonoid isolated from the leaves of Ginkgo biloba, and is characterized by its anti-inflammatory and anti-viral activities. Although numerous studies state that it has also antitumor activity, the anti-proliferative effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f284374b7b036170d55c4bb7b547069
https://doi.org/10.3892/ol.2017.6742
https://doi.org/10.3892/ol.2017.6742