Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Sang Dal Rhee"'
Encapsulation and Enhanced Delivery of Topoisomerase I Inhibitors in Functionalized Carbon Nanotubes
Autor:
Sieun Chae, Dahee Kim, Kyung-jin Lee, Dasol Lee, Young-O Kim, Yong Chae Jung, Sang Dal Rhee, Kwang Rok Kim, Jeong-O Lee, Sunjoo Ahn, Byumseok Koh
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 5938-5945 (2018)
Externí odkaz:
https://doaj.org/article/d00cad212f984af4a59c8b89270e9675
Autor:
Sung Bum Park, Ji Seon Park, Won Hoon Jung, Hee Youn Kim, Hyun Jung Kwak, Jin Hee Ahn, Kyoung-Jin Choi, Yoon-Ju Na, Sunhwa Choi, Sang Dal Rhee, Ki Young Kim
Publikováno v:
Journal of Pharmacological Sciences, Vol 131, Iss 4, Pp 241-250 (2016)
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inactive cortisone to the active cortisol. 11β-HSD1 may be involved in the resolution of inflammation. In the present study, we investigate the anti-inflammatory effects of 2-(3-benzoyl)-
Externí odkaz:
https://doaj.org/article/31767b0d9ce24015a23b0cf8612f56c5
Autor:
Byung Kil Park, Eun-Ah Lee, Hee-Youn Kim, Jun Choul Lee, Koon Soon Kim, Won Hoon Jeong, Ki Young Kim, Bon Jeong Ku, Sang Dal Rhee
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Mitogen inducible gene-6 (Mig-6) is a feedback inhibitor of epidermal growth factor receptor (EGFR) signaling pathway. The liver-specific knockout mice of the Mig-6 gene (Mig-6d/d) showed hepatomegaly and increased hypercholesterolemia. In this study
Externí odkaz:
https://doaj.org/article/b5e9bf84b83b482b9aa7e192cca40c5b
Autor:
Myoung Sook Han, Yu-Mi Lim, Wenying Quan, Jung Ran Kim, Kun Wook Chung, Mira Kang, Sunshin Kim, Sun Young Park, Joong-Soo Han, Shin-Young Park, Hyae Gyeong Cheon, Sang Dal Rhee, Tae-Sik Park, Myung-Shik Lee
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 6, Pp 1234-1246 (2011)
The mechanism of FFA-induced insulin resistance is not fully understood. We have searched for effector molecules(s) in FFA-induced insulin resistance. Palmitic acid (PA) but not oleic acid (OA) induced insulin resistance in L6 myotubes through C-Jun
Externí odkaz:
https://doaj.org/article/d29a593634ab49489b0584416e905365
Autor:
Jun Choul Lee, Byung Kil Park, Sorim Choung, Ji Min Kim, Kyong Hye Joung, Ju Hee Lee, Koon Soon Kim, Hyun Jin Kim, Jae-Wook Jeong, Sang Dal Rhee, Bon Jeong Ku
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114782 (2014)
Mitogen-inducible gene 6 (Mig-6) is a negative feedback inhibitor of epidermal growth factor receptor (EGFR) signaling. We previously found that Mig-6 plays a critical role in the regulation of cholesterol homeostasis and in bile acid synthesis. In t
Externí odkaz:
https://doaj.org/article/3cfde181a1b34a0a8e7abee16fddd8ff
Autor:
Seunga Choi, Hyeongseok Yun, Jungeun Yu, Tae-uk Ha, Hyoeun Jeon, Sumi Kim, Sang Dal Rhee, Bongjin Shin, Jaerang Rho, Eui-Soon Park, Jiyeon Yu, Yongwon Choi, Nari Lee
Publikováno v:
Molecules and Cells
The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is the master transcriptional regulator in adipogenesis. PPARγ forms a heterodimer with another nuclear receptor, retinoid X receptor (RXR), to form an active transcriptiona
Autor:
Byumseok Koh, Dahee Kim, Kwang Rok Kim, Sungsub Kim, Sang Dal Rhee, Won Hoon Jung, Ki-Young Kim, Hi Youn Kim
Publikováno v:
Oncology Letters
XAV939, a tankyrase inhibitor, exerts an anticancer effect in 3-dimensional (3D) cultured SW480 cells, however this is not exhibited in 2-dimensional (2D) cultured SW480 cells. In the current study, XAV939 induced a 3.7-fold increase in cellular apop
Encapsulation and Enhanced Delivery of Topoisomerase I Inhibitors in Functionalized Carbon Nanotubes
Autor:
Kwang Rok Kim, Yong Chae Jung, Kyung-jin Lee, Byumseok Koh, Jeong-O Lee, Young-O Kim, Dahee Kim, Sunjoo Ahn, Dasol Lee, Sieun Chae, Sang Dal Rhee
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 5938-5945 (2018)
ACS Omega
ACS Omega
The topoisomerase I inhibitors SN-38 and camptothecin (CPT) have shown potent anticancer activity, but water insolubility and metabolic instability limits their clinical application. Utilizing carbon nanotubes as a protective shell for water-insolubl
Autor:
Hye-Rim Seong, Ki Young Kim, Eun-Ah Lee, Sungsub Kim, Dong-In Lee, Hee-Yoen Kim, Sang Dal Rhee, Sung-Hoon Ahn, Won Hoon Jung
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:20-25
TALLYHO/Jng (TH) mice reveal hypercholesterolemia at an early age before their plasma glucose levels have increased. The increased plasma cholesterol should be related to bile acids (BAs) metabolism, because cholesterol is the precursor of BAs and BA
Autor:
Kyoung Jin Choi, Hye-Rim Sung, Won Hoon Jung, Ki Young Kim, Hee Youn Kim, Yoon-Ju Na, Sang Dal Rhee, Sung-Bum Park
Publikováno v:
Apoptosis. 22:1441-1453
Dry eye syndrome (DES) is a disorder of the eye due to tear deficiency or excessive evaporation that causes damage to the eye and is associated with discomfort and dryness. 11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) is an enzyme that converts in