Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sang Chun Ji"'
Autor:
Eunwoo Kim, Andrew Hyoungjin Kim, Yujin Lee, Sang Chun Ji, Joo‐Youn Cho, Kyung‐Sang Yu, Jae‐Yong Chung
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1955-1966 (2021)
Abstract Metformin is a major treatment for type 2 diabetes. This study was conducted to investigate the impact of gut microbiome dysbiosis on the pharmacokinetics and antihyperglycemic effects of metformin. Healthy adult males aged 19–45 years wit
Externí odkaz:
https://doaj.org/article/dc061bc9d28641c8beac6b8d8bb5e642
Autor:
Jung Sunwoo, Sang Chun Ji, Andrew HyoungJin Kim, Kyung‐Sang Yu, Joo‐Youn Cho, In‐Jin Jang, SeungHwan Lee
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 752-760 (2020)
The pharmacokinetic (PK) properties of drugs are affected in several ways by interactions with microbiota. The aim of this study was to investigate the effects of oral vancomycin on the gut microbiota and, consequently, on the PKs of simvastatin. An
Externí odkaz:
https://doaj.org/article/650f9b78d2e14d45b6cb97602781ba89
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Several classes of antibiotics have reduced the mortality caused by infectious diseases; however, orally administered antibiotics alter the composition of gut microbiota, leading to dysbiosis-related disease. Therefore, in this study, we used 16S rRN
Externí odkaz:
https://doaj.org/article/d2d94c75ed9342a5b3ec310e53b99762
Autor:
Kyoung Hee Han, Bora Kim, Sang Chun Ji, Hee Gyung Kang, Hae Il Cheong, Joo-Youn Cho, Il-Soo Ha
Publikováno v:
Metabolites, Vol 10, Iss 4, p 169 (2020)
While a complex network of cellular and molecular events is known to be involved in the pathophysiological mechanism of chronic kidney disease (CKD), the divergence point between reversal and progression and the event that triggers CKD progression ar
Externí odkaz:
https://doaj.org/article/782a7219e224458d86c015f66d2e4f83
Autor:
Sang Hoon Yun, Sang Chun Ji, Heung Jin Jeon, Xun Wang, Si Wouk Kim, Geunu Bak, Younghoon Lee, Heon M Lim
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45236 (2012)
Cnu (an OriC-binding nucleoid protein) associates with H-NS. A variant of Cnu was identified as a key factor for filamentous growth of a wild-type Escherichia coli strain at 37°C. This variant (CnuK9E) bears a substitution of a lysine to glutamic ac
Externí odkaz:
https://doaj.org/article/5ed41756ba2640e990e8da4358b1ca22
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17646 (2011)
Quantitative analyses of the 5' end of gal transcripts indicate that transcription from the galactose operon P1 promoter is higher during cell division. When cells are no longer dividing, however, transcription is initiated more often from the P2 pro
Externí odkaz:
https://doaj.org/article/83654f78f32041a7b9017a81271ab863
Publikováno v:
Clinical Pharmacokinetics. 62:599-608
Autor:
Inyoung Hwang, Sang Chun Ji, Jaeseong Oh, Hyojin Kim, Hyunju Cha, John Kim, Chang‐Seok Lee, Kyung‐Sang Yu, SeungHwan Lee
Publikováno v:
Alimentary Pharmacology & Therapeutics. 57:763-772
Autor:
Inyoung Hwang, Sang Chun Ji, Jaeseong Oh, Hyojin Kim, Hyunju Cha, John Kim, Chang‐Seok Lee, Kyung‐Sang Yu, SeungHwan Lee
Publikováno v:
Alimentary Pharmacology & Therapeutics. 57
Autor:
In-Jin Jang, Kyung Sang Yu, Sang Chun Ji, Andrew Hyoung Jin Kim, Sang In Park, Seo Hyun Yoon, Jae Young Chung, Jaeseong Oh, Seung-Hwan Lee, Sang Won Lee
Publikováno v:
The Pharmacogenomics Journal. 20:792-800
High pharmacokinetic variability of voriconazole is mainly explained by CYP2C19 phenotype, but there are still unknown factors affecting the variability. In this study, the effect of solute carrier organic anion transporter family member 2B1 (SLCO2B1